IT7824616A0 - Benzafenon-anti-ossime, diazepin-n-ossidi e loro impiegocome prodotti farmaceutici e come intermedi per prodotti farmaceutici. - Google Patents

Benzafenon-anti-ossime, diazepin-n-ossidi e loro impiegocome prodotti farmaceutici e come intermedi per prodotti farmaceutici.

Info

Publication number
IT7824616A0
IT7824616A0 IT7824616A IT2461678A IT7824616A0 IT 7824616 A0 IT7824616 A0 IT 7824616A0 IT 7824616 A IT7824616 A IT 7824616A IT 2461678 A IT2461678 A IT 2461678A IT 7824616 A0 IT7824616 A0 IT 7824616A0
Authority
IT
Italy
Prior art keywords
pharmaceutical products
benzaphenon
oxymes
diazepin
intermediates
Prior art date
Application number
IT7824616A
Other languages
English (en)
Other versions
IT1098339B (it
Original Assignee
E I Du Pont De Numours And Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E I Du Pont De Numours And Co filed Critical E I Du Pont De Numours And Co
Publication of IT7824616A0 publication Critical patent/IT7824616A0/it
Application granted granted Critical
Publication of IT1098339B publication Critical patent/IT1098339B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C07D273/02—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having two nitrogen atoms and only one oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • C07D239/76—N-oxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT24616/78A 1977-06-16 1978-06-15 Bezafenon-anti-ossime,diazepin-n-ossidi e loro impiego come prodotti farmaceutici e come intermedi per prodotti farmaceutici IT1098339B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/807,075 US4182760A (en) 1977-06-16 1977-06-16 Benzophenone anti-oximes, diazepin-N-oxides, and their use as pharmaceutical agents and as intermediates for pharmaceutical agents

Publications (2)

Publication Number Publication Date
IT7824616A0 true IT7824616A0 (it) 1978-06-15
IT1098339B IT1098339B (it) 1985-09-07

Family

ID=25195504

Family Applications (1)

Application Number Title Priority Date Filing Date
IT24616/78A IT1098339B (it) 1977-06-16 1978-06-15 Bezafenon-anti-ossime,diazepin-n-ossidi e loro impiego come prodotti farmaceutici e come intermedi per prodotti farmaceutici

Country Status (4)

Country Link
US (1) US4182760A (it)
EP (1) EP0000332A3 (it)
JP (1) JPS545956A (it)
IT (1) IT1098339B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472435A (en) * 1980-07-31 1984-09-18 Hoffman-La Roche Inc. Benzophenone derivatives useful in treating heart failure
US4461728A (en) * 1981-12-23 1984-07-24 Hoechst Roussel Pharmaceuticals Inc. Preparation of 4-phenyl-1,3-benzodiazepins
US4374067A (en) * 1981-12-23 1983-02-15 Hoechst-Roussel Pharmaceuticals, Inc. Intermediates for the preparation of 4-phenyl-1,3-benzodiazepins and methods for preparing the intermediates
JP2020023441A (ja) * 2016-11-02 2020-02-13 国立大学法人九州大学 Ｅｇｆｒ阻害及び腫瘍治療に有用な新規化合物
RU2687556C1 (ru) * 2018-12-24 2019-05-15 Акционерное общество "Федеральный научно-производственный центр "Алтай" Способ получения 7-хлор-1,3-дигидро-1-метил-5-фенил-2Н-1,4-бензодиазепин-2-она

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3453279A (en) * 1963-11-27 1969-07-01 Hoffmann La Roche 2-dihalo lower alkyl-4-phenyl-quinazoline 3-oxide
US3453326A (en) * 1963-11-27 1969-07-01 Hoffmann La Roche 2'-benzoyl-2,2-dihaloacetanilide oxime
US3321467A (en) * 1963-11-27 1967-05-23 Hoffmann La Roche 3-halo-1, 4-benzodiazepin-2-ones
US3398139A (en) * 1964-04-10 1968-08-20 Hoffmann La Roche Process for preparing 2-amino-benzodiazepines
DE2542251A1 (de) * 1975-09-23 1977-03-31 Merck Patent Gmbh 3-fluorbenzodiazepine und verfahren zu ihrer herstellung
DE2460360A1 (de) * 1974-12-20 1976-06-24 Merck Patent Gmbh 3-fluorbenzodiazepine und verfahren zu ihrer herstellung
SE7606676L (sv) * 1975-07-21 1977-01-22 Du Pont Bensodiazepiner

Also Published As

Publication number Publication date
US4182760A (en) 1980-01-08
EP0000332A3 (en) 1979-05-30
IT1098339B (it) 1985-09-07
EP0000332A2 (en) 1979-01-24
JPS545956A (en) 1979-01-17

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