IT202000001213A1 - Dispositivo microfluidico e metodi per utilizzare detto dispositivo - Google Patents

Dispositivo microfluidico e metodi per utilizzare detto dispositivo

Info

Publication number
IT202000001213A1
IT202000001213A1 IT102020000001213A IT202000001213A IT202000001213A1 IT 202000001213 A1 IT202000001213 A1 IT 202000001213A1 IT 102020000001213 A IT102020000001213 A IT 102020000001213A IT 202000001213 A IT202000001213 A IT 202000001213A IT 202000001213 A1 IT202000001213 A1 IT 202000001213A1
Authority
IT
Italy
Prior art keywords
methods
microfluidic
microfluidic device
Prior art date
Application number
IT102020000001213A
Other languages
English (en)
Inventor
Angelis Francesco De
Michele Dipalo
Francesco Tantussi
Andrea Barbaglia
Andrea Toma
Original Assignee
Fondazione St Italiano Tecnologia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fondazione St Italiano Tecnologia filed Critical Fondazione St Italiano Tecnologia
Priority to IT102020000001213A priority Critical patent/IT202000001213A1/it
Priority to EP21706705.7A priority patent/EP4094079A1/en
Priority to US17/793,690 priority patent/US20230060283A1/en
Priority to PCT/IB2021/050452 priority patent/WO2021148975A1/en
Publication of IT202000001213A1 publication Critical patent/IT202000001213A1/it

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/168—Specific optical properties, e.g. reflective coatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optical Measuring Cells (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
IT102020000001213A 2020-01-22 2020-01-22 Dispositivo microfluidico e metodi per utilizzare detto dispositivo IT202000001213A1 (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT102020000001213A IT202000001213A1 (it) 2020-01-22 2020-01-22 Dispositivo microfluidico e metodi per utilizzare detto dispositivo
EP21706705.7A EP4094079A1 (en) 2020-01-22 2021-01-21 Microfluidic device and methods for using such device
US17/793,690 US20230060283A1 (en) 2020-01-22 2021-01-21 Microfluidic device and methods for using such device
PCT/IB2021/050452 WO2021148975A1 (en) 2020-01-22 2021-01-21 Microfluidic device and methods for using such device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102020000001213A IT202000001213A1 (it) 2020-01-22 2020-01-22 Dispositivo microfluidico e metodi per utilizzare detto dispositivo

Publications (1)

Publication Number Publication Date
IT202000001213A1 true IT202000001213A1 (it) 2021-07-22

Family

ID=70480396

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102020000001213A IT202000001213A1 (it) 2020-01-22 2020-01-22 Dispositivo microfluidico e metodi per utilizzare detto dispositivo

Country Status (4)

Country Link
US (1) US20230060283A1 (it)
EP (1) EP4094079A1 (it)
IT (1) IT202000001213A1 (it)
WO (1) WO2021148975A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220032296A1 (en) * 2018-09-19 2022-02-03 Fondazione Istituto Italiano Di Tecnologia Microfluidic devices and methods for using the devices

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020058833A1 (en) * 2018-09-19 2020-03-26 Fondazione Istituto Italiano Di Tecnologia Microfluidic device and methods for using said device

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020058833A1 (en) * 2018-09-19 2020-03-26 Fondazione Istituto Italiano Di Tecnologia Microfluidic device and methods for using said device

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ANDREA CEREA ET AL: "Selective intracellular delivery and intracellular recordings combined in MEA biosensors", LAB ON A CHIP, vol. 18, no. 22, 1 January 2018 (2018-01-01), pages 3492 - 3500, XP055589811, ISSN: 1473-0197, DOI: 10.1039/C8LC00435H *
ANDREA CEREA ET AL: "Selective intracellular delivery and intracellular recordings combined on MEA biosensors", ARXIV.ORG, CORNELL UNIVERSITY LIBRARY, 201 OLIN LIBRARY CORNELL UNIVERSITY ITHACA, NY 14853, 23 August 2018 (2018-08-23), XP081176106 *
BALLINI MARCO ET AL: "A 1024-Channel CMOS Microelectrode Array With 26,400 Electrodes for Recording and Stimulation of Electrogenic Cells In Vitro", IEEE JOURNAL OF SOLID-STATE CIRCUITS, IEEE, USA, vol. 49, no. 11, 1 November 2014 (2014-11-01), pages 2705 - 2719, XP011562675, ISSN: 0018-9200, [retrieved on 20141024], DOI: 10.1109/JSSC.2014.2359219 *
JIAYI ZHANG ET AL: "Optical Detection of Brain Cell Activity Using Plasmonic Gold Nanoparticles", NANO LETTERS, vol. 9, no. 2, 11 February 2009 (2009-02-11), US, pages 519 - 524, XP055589405, ISSN: 1530-6984, DOI: 10.1021/nl801891q *
MICHELE DIPALO ET AL: "Intracellular and Extracellular Recording of Spontaneous Action Potentials in Mammalian Neurons and Cardiac Cells with 3D Plasmonic Nanoelectrodes", NANO LETTERS, vol. 17, no. 6, 24 May 2017 (2017-05-24), US, pages 3932 - 3939, XP055501265, ISSN: 1530-6984, DOI: 10.1021/acs.nanolett.7b01523 *
MICHELE DIPALO ET AL: "Plasmonic meta-electrodes allow intracellular recordings at network level on high-density CMOS-multi-electrode arrays", NATURE NANOTECHNOLOGY, 13 August 2018 (2018-08-13), London, XP055502579, ISSN: 1748-3387, DOI: 10.1038/s41565-018-0222-z *
PARAMESWARAN RAMYA ET AL: "Scalable breakthrough", NATURE NANOTECHNOLOGY, NATURE PUB. GROUP, INC, LONDON, vol. 13, no. 10, 13 August 2018 (2018-08-13), pages 875 - 876, XP036607758, ISSN: 1748-3387, [retrieved on 20180813], DOI: 10.1038/S41565-018-0248-2 *

Also Published As

Publication number Publication date
WO2021148975A1 (en) 2021-07-29
EP4094079A1 (en) 2022-11-30
US20230060283A1 (en) 2023-03-02

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