IT201900023946A1 - Metodo per determinare una prognosi di sopravvivenza a lungo termine di pazienti di cancro al seno, sulla base di algoritmi che modellizzano reti biologiche - Google Patents
Metodo per determinare una prognosi di sopravvivenza a lungo termine di pazienti di cancro al seno, sulla base di algoritmi che modellizzano reti biologicheInfo
- Publication number
- IT201900023946A1 IT201900023946A1 IT102019000023946A IT201900023946A IT201900023946A1 IT 201900023946 A1 IT201900023946 A1 IT 201900023946A1 IT 102019000023946 A IT102019000023946 A IT 102019000023946A IT 201900023946 A IT201900023946 A IT 201900023946A IT 201900023946 A1 IT201900023946 A1 IT 201900023946A1
- Authority
- IT
- Italy
- Prior art keywords
- algorithms
- determining
- long
- breast cancer
- cancer patients
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 title 1
- 208000026310 Breast neoplasm Diseases 0.000 title 1
- 230000007774 longterm Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000004393 prognosis Methods 0.000 title 1
- 230000004083 survival effect Effects 0.000 title 1
Classifications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F18/00—Pattern recognition
- G06F18/20—Analysing
- G06F18/21—Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation
- G06F18/213—Feature extraction, e.g. by transforming the feature space; Summarisation; Mappings, e.g. subspace methods
- G06F18/2135—Feature extraction, e.g. by transforming the feature space; Summarisation; Mappings, e.g. subspace methods based on approximation criteria, e.g. principal component analysis
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N20/00—Machine learning
- G06N20/10—Machine learning using kernel methods, e.g. support vector machines [SVM]
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Data Mining & Analysis (AREA)
- Biomedical Technology (AREA)
- Theoretical Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Primary Health Care (AREA)
- Pathology (AREA)
- Epidemiology (AREA)
- Databases & Information Systems (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Computation (AREA)
- Artificial Intelligence (AREA)
- Software Systems (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Computing Systems (AREA)
- Mathematical Physics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT102019000023946A IT201900023946A1 (it) | 2019-12-13 | 2019-12-13 | Metodo per determinare una prognosi di sopravvivenza a lungo termine di pazienti di cancro al seno, sulla base di algoritmi che modellizzano reti biologiche |
US17/773,263 US20230145332A1 (en) | 2019-12-13 | 2020-11-23 | Method for determining a long-term survival prognosis of breast cancer patients, based on algorithms modelling biological networks |
EP20828554.4A EP4073803A1 (en) | 2019-12-13 | 2020-11-23 | Method for determining a long-term survival prognosis of breast cancer patients, based on algorithms modelling biological networks |
PCT/IB2020/061014 WO2021140373A1 (en) | 2019-12-13 | 2020-11-23 | Method for determining a long-term survival prognosis of breast cancer patients, based on algorithms modelling biological networks |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT102019000023946A IT201900023946A1 (it) | 2019-12-13 | 2019-12-13 | Metodo per determinare una prognosi di sopravvivenza a lungo termine di pazienti di cancro al seno, sulla base di algoritmi che modellizzano reti biologiche |
Publications (1)
Publication Number | Publication Date |
---|---|
IT201900023946A1 true IT201900023946A1 (it) | 2021-06-13 |
Family
ID=70155036
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT102019000023946A IT201900023946A1 (it) | 2019-12-13 | 2019-12-13 | Metodo per determinare una prognosi di sopravvivenza a lungo termine di pazienti di cancro al seno, sulla base di algoritmi che modellizzano reti biologiche |
Country Status (4)
Country | Link |
---|---|
US (1) | US20230145332A1 (it) |
EP (1) | EP4073803A1 (it) |
IT (1) | IT201900023946A1 (it) |
WO (1) | WO2021140373A1 (it) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019178217A1 (en) * | 2018-03-13 | 2019-09-19 | Baylor Research Institute | Methods and compositions for treating, diagnosing, and prognosing cancer |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ576428A (en) * | 2006-11-03 | 2012-04-27 | Baylor Res Inst | Diagnosis of metastatic melanoma and monitoring indicators of immunosuppression through blood leukocyte microarray analysis |
CA2737485A1 (en) * | 2008-10-10 | 2010-04-15 | Mount Sinai Hospital | Methods for classifying samples based on network modularity |
SG2014015028A (en) * | 2009-03-10 | 2014-07-30 | Agency Science Tech & Res | A method for identification, prediction and prognosis of cancer aggressiveness |
WO2013147330A1 (ko) * | 2012-03-26 | 2013-10-03 | 연세대학교 산학협력단 | 국소 진행형 위암에 대한 예후 예측 시스템 |
AU2013353839A1 (en) * | 2012-12-03 | 2015-06-18 | Almac Diagnostics Limited | Molecular diagnostic test for cancer |
US10679730B2 (en) * | 2013-05-28 | 2020-06-09 | The University Of Chicago | Prognostic and predictive breast cancer signature |
US20150331992A1 (en) * | 2014-05-15 | 2015-11-19 | Ramot At Tel-Aviv University Ltd. | Cancer prognosis and therapy based on syntheic lethality |
US10876167B2 (en) * | 2017-01-12 | 2020-12-29 | The Regents Of The University Of California | 12-gene prognostic signature for breast cancer survival |
US12062444B2 (en) * | 2017-12-12 | 2024-08-13 | The University Of Chicago | Methods and compositions related to triple-negative breast cancer |
CN108424969B (zh) * | 2018-06-06 | 2022-07-15 | 深圳市颐康生物科技有限公司 | 一种生物标志物、诊断或预估死亡风险的方法 |
-
2019
- 2019-12-13 IT IT102019000023946A patent/IT201900023946A1/it unknown
-
2020
- 2020-11-23 WO PCT/IB2020/061014 patent/WO2021140373A1/en unknown
- 2020-11-23 EP EP20828554.4A patent/EP4073803A1/en active Pending
- 2020-11-23 US US17/773,263 patent/US20230145332A1/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019178217A1 (en) * | 2018-03-13 | 2019-09-19 | Baylor Research Institute | Methods and compositions for treating, diagnosing, and prognosing cancer |
Non-Patent Citations (12)
Title |
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ALTER O.BROWN P.O.BOTSTEIN D.: "Singular value decomposition for genome-wide Expression Data processing and Modeling", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 97, no. 18, 2000, pages 10101 - 6, XP002962133, DOI: 10.1073/pnas.97.18.10101 |
BERRY M.DUMAIS S.O'BRIEN G.: "Using Linear Algebra for Intelligent Information retrieval", SIAM REVIEW, vol. 37, no. 4, 1995, pages 573 - 95, XP000572488, DOI: 10.1137/1037127 |
BISHOPCHRISTOPHER M.: "Pattern Recognition and Machine Learning", 2006, SPRINGER-VERLAG |
BRIAN D. LEHMANN ET AL: "Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection", PLOS ONE, vol. 11, no. 6, 16 June 2016 (2016-06-16), pages e0157368, XP055325113, DOI: 10.1371/journal.pone.0157368 * |
EVERITT B.S.DUNN G.: "Principal components Analysis. In applied Multi-variate Data Analysis", 2013, WILEY |
FONT-CLOS F.ZAPPERI S.C.A.M. GATE: "Topography of Epithelial-Mesenchymal Plasticity", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 115, no. 23, 2018, pages 5902 - 7 |
H BONSANG-KITZIS ET AL: "Biological network-driven gene selection identifies a stromal immune module as a key determinant of triple-negative breast carcinoma prognosis", ONCOIMMUNOLOGY, vol. 5, no. 1, 2 January 2016 (2016-01-02), US, pages e1061176, XP055719202, ISSN: 2162-4011, DOI: 10.1080/2162402X.2015.1061176 * |
LEHMANN B.D.BAUER J.A.CHEN X.SANDERS M.E.CHAKRAVARTHY A.B.SHYR Y.PIETENPOL J.A.: "Identification of Human Triple-negative Breast Cancer Subtypes and Preclinical Models for Selection of targeted therapies", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 121, no. 7, 2011, pages 2750 - 67, XP002690196, DOI: 10.1172/JCI45014 |
OZTURK KIVILCIM ET AL: "The Emerging Potential for Network Analysis to Inform Precision Cancer Medicine", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, vol. 430, no. 18, 15 June 2018 (2018-06-15), pages 2875 - 2899, XP085446856, ISSN: 0022-2836, DOI: 10.1016/J.JMB.2018.06.016 * |
PAIK SSHAK STANG GKIM CBAKER J ET AL.: "A multitene assay to pret recurrence of tamoxifen-treated, node-negative breast cancer", N ENGL J MED, vol. 351, 2004, pages 2817 - 2826 |
SUN MIN ET AL: "An eight-lncRNA signature predicts survival of breast cancer patients: a comprehensive study based on weighted gene co-expression network analysis and competing endogenous RNA network", BREAST CANCER RESEARCH AND TREATMENT, SPRINGER , NY, US, vol. 175, no. 1, 4 February 2019 (2019-02-04), pages 59 - 75, XP036771571, ISSN: 0167-6806, [retrieved on 20190204], DOI: 10.1007/S10549-019-05147-6 * |
VAN'T VEER LJ, HVAN DE VIJVER MJHE YDHART AA ET AL.: "gene expression profiling predicts clinical outcome of breast cancer", NATURE, vol. 415, 2002, pages 530 - 536, XP008138701, DOI: 10.1038/415530a |
Also Published As
Publication number | Publication date |
---|---|
WO2021140373A1 (en) | 2021-07-15 |
US20230145332A1 (en) | 2023-05-11 |
EP4073803A1 (en) | 2022-10-19 |
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