IT201900020492A1 - Dispersioni solide di sali dell’acido ursolico - Google Patents
Dispersioni solide di sali dell’acido ursolicoInfo
- Publication number
- IT201900020492A1 IT201900020492A1 IT102019000020492A IT201900020492A IT201900020492A1 IT 201900020492 A1 IT201900020492 A1 IT 201900020492A1 IT 102019000020492 A IT102019000020492 A IT 102019000020492A IT 201900020492 A IT201900020492 A IT 201900020492A IT 201900020492 A1 IT201900020492 A1 IT 201900020492A1
- Authority
- IT
- Italy
- Prior art keywords
- acid salts
- ursolic acid
- solid dispersions
- dispersions
- ursolic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102019000020492A IT201900020492A1 (it) | 2019-11-06 | 2019-11-06 | Dispersioni solide di sali dell’acido ursolico |
| US17/755,720 US20220387361A1 (en) | 2019-11-06 | 2020-10-30 | Solid dispersion of ursolic acid and potassium salt |
| EP20806942.7A EP4054529A1 (en) | 2019-11-06 | 2020-10-30 | Solid dispersions of ursolic acid potassium salt |
| AU2020381309A AU2020381309A1 (en) | 2019-11-06 | 2020-10-30 | Solid dispersions of ursolic acid potassium salt |
| CA3157303A CA3157303A1 (en) | 2019-11-06 | 2020-10-30 | Solid dispersions of ursolic acid potassium salt |
| JP2022525758A JP2023500331A (ja) | 2019-11-06 | 2020-10-30 | ウルソール酸カリウム塩の固体分散体 |
| PCT/EP2020/080548 WO2021089433A1 (en) | 2019-11-06 | 2020-10-30 | Solid dispersions of ursolic acid potassium salt |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102019000020492A IT201900020492A1 (it) | 2019-11-06 | 2019-11-06 | Dispersioni solide di sali dell’acido ursolico |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT201900020492A1 true IT201900020492A1 (it) | 2021-05-06 |
Family
ID=69903776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT102019000020492A IT201900020492A1 (it) | 2019-11-06 | 2019-11-06 | Dispersioni solide di sali dell’acido ursolico |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220387361A1 (it) |
| EP (1) | EP4054529A1 (it) |
| JP (1) | JP2023500331A (it) |
| AU (1) | AU2020381309A1 (it) |
| CA (1) | CA3157303A1 (it) |
| IT (1) | IT201900020492A1 (it) |
| WO (1) | WO2021089433A1 (it) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101095684A (zh) * | 2006-06-28 | 2008-01-02 | 黑龙江大学 | 熊果酸磷脂复合物及其制备方法和应用 |
-
2019
- 2019-11-06 IT IT102019000020492A patent/IT201900020492A1/it unknown
-
2020
- 2020-10-30 US US17/755,720 patent/US20220387361A1/en active Pending
- 2020-10-30 EP EP20806942.7A patent/EP4054529A1/en active Pending
- 2020-10-30 WO PCT/EP2020/080548 patent/WO2021089433A1/en unknown
- 2020-10-30 JP JP2022525758A patent/JP2023500331A/ja active Pending
- 2020-10-30 CA CA3157303A patent/CA3157303A1/en active Pending
- 2020-10-30 AU AU2020381309A patent/AU2020381309A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101095684A (zh) * | 2006-06-28 | 2008-01-02 | 黑龙江大学 | 熊果酸磷脂复合物及其制备方法和应用 |
Non-Patent Citations (7)
| Title |
|---|
| AMIDON ET AL., PHARM RES., vol. 12, no. 3, March 1995 (1995-03-01), pages 413 - 20 |
| CURRENT MEDICINAL CHEMISTRY, vol. 24, 2017, pages 1 - 10 |
| J. PI ET AL., CURRENT DRUG DELIVERY, vol. 13, no. 8, 2016, pages 1358 - 1366 |
| KLEIN, S., AAPS JOURNAL, vol. 12, no. 3, 2010, pages 397 - 406 |
| REMINGTON: "The Science and practice of Pharmacy", 2013, PHARMACEUTICAL PRESS |
| WU W.OSWALD ET AL., JOUMAL IN SOLUTION CHEMISTRY, vol. 27, no. 6, pages 521 - 531 |
| XIAO JU ZHOU ET AL: "Preparation and Body Distribution of Freeze-Dried Powder of Ursolic Acid Phospholipid Nanoparticles", DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, vol. 35, no. 3, 1 March 2009 (2009-03-01), US, pages 305 - 310, XP055707908, ISSN: 0363-9045, DOI: 10.1080/03639040802302165 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023500331A (ja) | 2023-01-05 |
| WO2021089433A1 (en) | 2021-05-14 |
| AU2020381309A1 (en) | 2022-06-16 |
| US20220387361A1 (en) | 2022-12-08 |
| EP4054529A1 (en) | 2022-09-14 |
| CA3157303A1 (en) | 2021-05-14 |
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