IT201900012555A1 - Metodo per coadiuvare la diagnosi precoce dell’adenocarcinoma del pancreas - Google Patents

Metodo per coadiuvare la diagnosi precoce dell’adenocarcinoma del pancreas

Info

Publication number
IT201900012555A1
IT201900012555A1 IT102019000012555A IT201900012555A IT201900012555A1 IT 201900012555 A1 IT201900012555 A1 IT 201900012555A1 IT 102019000012555 A IT102019000012555 A IT 102019000012555A IT 201900012555 A IT201900012555 A IT 201900012555A IT 201900012555 A1 IT201900012555 A1 IT 201900012555A1
Authority
IT
Italy
Prior art keywords
assist
early diagnosis
pancreas adenocarcinoma
adenocarcinoma
pancreas
Prior art date
Application number
IT102019000012555A
Other languages
English (en)
Inventor
Giulio Caracciolo
Daniela Pozzi
Sara Palchetti
Luca Digiacomo
Damiano Caputo
Roberto Coppola
Original Assignee
Sapienza Univ Di Roma
Univ Campus Bio Medico Di Roma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sapienza Univ Di Roma, Univ Campus Bio Medico Di Roma filed Critical Sapienza Univ Di Roma
Priority to IT102019000012555A priority Critical patent/IT201900012555A1/it
Priority to PCT/IB2020/056251 priority patent/WO2021014243A1/en
Priority to EP20737059.4A priority patent/EP4004941A1/en
Priority to CN202080053417.8A priority patent/CN115038967A/zh
Priority to US17/629,091 priority patent/US20220236274A1/en
Publication of IT201900012555A1 publication Critical patent/IT201900012555A1/it

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G06F17/15—Correlation function computation including computation of convolution operations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Data Mining & Analysis (AREA)
  • Medical Informatics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Databases & Information Systems (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Software Systems (AREA)
  • Pure & Applied Mathematics (AREA)
  • Mathematical Optimization (AREA)
  • Mathematical Physics (AREA)
  • Mathematical Analysis (AREA)
  • Computational Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
IT102019000012555A 2019-07-22 2019-07-22 Metodo per coadiuvare la diagnosi precoce dell’adenocarcinoma del pancreas IT201900012555A1 (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT102019000012555A IT201900012555A1 (it) 2019-07-22 2019-07-22 Metodo per coadiuvare la diagnosi precoce dell’adenocarcinoma del pancreas
PCT/IB2020/056251 WO2021014243A1 (en) 2019-07-22 2020-07-02 A method to assist in the early diagnosis of pancreatic adenocarcinoma
EP20737059.4A EP4004941A1 (en) 2019-07-22 2020-07-02 A method to assist in the early diagnosis of pancreatic adenocarcinoma
CN202080053417.8A CN115038967A (zh) 2019-07-22 2020-07-02 胰腺癌早期诊断的辅助方法
US17/629,091 US20220236274A1 (en) 2019-07-22 2020-07-02 A method to assist in the early diagnosis of pancreatic adenocarcinoma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102019000012555A IT201900012555A1 (it) 2019-07-22 2019-07-22 Metodo per coadiuvare la diagnosi precoce dell’adenocarcinoma del pancreas

Publications (1)

Publication Number Publication Date
IT201900012555A1 true IT201900012555A1 (it) 2021-01-22

Family

ID=68988104

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102019000012555A IT201900012555A1 (it) 2019-07-22 2019-07-22 Metodo per coadiuvare la diagnosi precoce dell’adenocarcinoma del pancreas

Country Status (5)

Country Link
US (1) US20220236274A1 (it)
EP (1) EP4004941A1 (it)
CN (1) CN115038967A (it)
IT (1) IT201900012555A1 (it)
WO (1) WO2021014243A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7215682B2 (ja) * 2019-09-09 2023-01-31 ａｉｗｅｌｌ株式会社 情報処理システムおよびプログラム

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
CAPUTO ET AL.: "A protein crown-enabled blood test for early cancer detection", NANOSCALE, vol. 9, 2017, pages 349 - 354
COLAPICCHIONI ET AL.: "personalized liposome-protein crown in the blood of breast, gastric and pancreatic cancer patients", INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY, vol. 75, 2016, pages 180 - 187, XP029537283, DOI: 10.1016/j.biocel.2015.09.002
D. CAPUTO ET AL: "A protein corona-enabled blood test for early cancer detection", NANOSCALE, vol. 9, no. 1, 1 January 2017 (2017-01-01), United Kingdom, pages 349 - 354, XP055678638, ISSN: 2040-3364, DOI: 10.1039/C6NR05609A *
GARCÍA VENCE MARÍA ET AL: "Potential clinical applications of the personalized, disease-specific protein corona on nanoparticles", CLINICA CHIMICA ACTA, ELSEVIER BV, AMSTERDAM, NL, vol. 501, 31 October 2019 (2019-10-31), pages 102 - 111, XP085994475, ISSN: 0009-8981, [retrieved on 20191031], DOI: 10.1016/J.CCA.2019.10.027 *
HAJIPOUR, MOHAMMAD JAVAD ET AL.: "Personalized disease-specific protein crown influences the therapeutic impact of graphene oxide", NANOSCALE, vol. 7.19, 2015, pages 8978 - 8994, XP055424912, DOI: 10.1039/C5NR00520E
LUCA DIGIACOMO ET AL: "The biomolecular corona of gold nanoparticles in a controlled microfluidic environment", LAB ON A CHIP, vol. 19, no. 15, 23 July 2019 (2019-07-23), pages 2557 - 2567, XP055678687, ISSN: 1473-0197, DOI: 10.1039/C9LC00341J *
XIAOHUA HUANG ET AL: "Gold Nanoparticle Based Platforms for Circulating Cancer Marker Detection", NANOTHERANOSTICS, vol. 1, no. 1, 1 January 2017 (2017-01-01), pages 80 - 102, XP055678689, ISSN: 2206-7418, DOI: 10.7150/ntno.18216 *
YACHIDA SJONES SBOZIC I ET AL.: "Distant metastasis occurs late during the genetic evolution of pancreatic cancer", NATURE, vol. 467, no. 7319, 2010, pages 1114 - 7, XP055501147, DOI: 10.1038/nature09515
YAN TECK HO ET AL: "Protein Corona Formed from Different Blood Plasma Proteins Affects the Colloidal Stability of Nanoparticles Differently", BIOCONJUGATE CHEMISTRY, vol. 29, no. 11, 22 October 2018 (2018-10-22), US, pages 3923 - 3934, XP055678878, ISSN: 1043-1802, DOI: 10.1021/acs.bioconjchem.8b00743 *

Also Published As

Publication number Publication date
CN115038967A (zh) 2022-09-09
EP4004941A1 (en) 2022-06-01
US20220236274A1 (en) 2022-07-28
WO2021014243A1 (en) 2021-01-28

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