IT201700100483A1 - Ossidazione selettiva dell’acido iodesossicolico - Google Patents

Ossidazione selettiva dell’acido iodesossicolico

Info

Publication number
IT201700100483A1
IT201700100483A1 IT102017000100483A IT201700100483A IT201700100483A1 IT 201700100483 A1 IT201700100483 A1 IT 201700100483A1 IT 102017000100483 A IT102017000100483 A IT 102017000100483A IT 201700100483 A IT201700100483 A IT 201700100483A IT 201700100483 A1 IT201700100483 A1 IT 201700100483A1
Authority
IT
Italy
Prior art keywords
iodesexicolic
acid
selective oxidation
selective
oxidation
Prior art date
Application number
IT102017000100483A
Other languages
English (en)
Inventor
Emanuele Attolino
Simone Mantegazza
Francesco Messana
Gabriele Razzetti
Original Assignee
Dipharma Francis Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dipharma Francis Srl filed Critical Dipharma Francis Srl
Priority to IT102017000100483A priority Critical patent/IT201700100483A1/it
Publication of IT201700100483A1 publication Critical patent/IT201700100483A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
IT102017000100483A 2017-09-07 2017-09-07 Ossidazione selettiva dell’acido iodesossicolico IT201700100483A1 (it)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IT102017000100483A IT201700100483A1 (it) 2017-09-07 2017-09-07 Ossidazione selettiva dell’acido iodesossicolico

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000100483A IT201700100483A1 (it) 2017-09-07 2017-09-07 Ossidazione selettiva dell’acido iodesossicolico

Publications (1)

Publication Number Publication Date
IT201700100483A1 true IT201700100483A1 (it) 2019-03-07

Family

ID=60991366

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000100483A IT201700100483A1 (it) 2017-09-07 2017-09-07 Ossidazione selettiva dell’acido iodesossicolico

Country Status (1)

Country Link
IT (1) IT201700100483A1 (it)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013036835A1 (en) * 2011-09-08 2013-03-14 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CN105777835A (zh) * 2014-12-25 2016-07-20 重庆药友制药有限责任公司 一种制备鹅去氧胆酸类似物的方法
CN106749468A (zh) * 2016-12-08 2017-05-31 青州市欣泰生物制品有限公司 一种奥贝胆酸的制备方法
CN107245089A (zh) * 2017-02-22 2017-10-13 厦门海乐景生化有限公司 一种奥贝胆酸的制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013036835A1 (en) * 2011-09-08 2013-03-14 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CN105777835A (zh) * 2014-12-25 2016-07-20 重庆药友制药有限责任公司 一种制备鹅去氧胆酸类似物的方法
CN106749468A (zh) * 2016-12-08 2017-05-31 青州市欣泰生物制品有限公司 一种奥贝胆酸的制备方法
CN107245089A (zh) * 2017-02-22 2017-10-13 厦门海乐景生化有限公司 一种奥贝胆酸的制备方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HEIDY HERRERA ET AL: "Structural Modifications of Deoxycholic Acid to Obtain Three Known Brassinosteroid Analogues and Full NMR Spectroscopic Characterization [Article 1139]", MOLECULES, vol. 21, no. 9, 27 August 2016 (2016-08-27), pages 1 - 12, XP055469755, DOI: 10.3390/molecules21091139 *
IIDA T ET AL: "Potential bile acid metabolites. 20. A new synthetic route to stereoisomeric 3,6,-dihydroxy- and 6-hydroxy-5@a-cholanoic acids", STEROIDS, ELSEVIER SCIENCE PUBLISHERS, NEW YORK, NY, US, vol. 58, no. 8, 1 August 1993 (1993-08-01), pages 362 - 369, XP023431573, ISSN: 0039-128X, [retrieved on 19930801], DOI: 10.1016/0039-128X(93)90039-P *
WEI-SHAN ZHOU ET AL: "Stereocontrolled conversion of hyodeoxycholic acid into chenodeoxycholic acid and ursodeoxycholic acid", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 1, no. 1, 1 January 1990 (1990-01-01), GB, pages 1 - 3, XP055320230, ISSN: 0300-922X, DOI: 10.1039/p19900000001 *
YANG YA-XI ET AL: "Synthesis of 5[alpha]-cholestan-6-one derivatives and their inhibitory activities of NO production in activated microglia: Discovery of a novel neuroinflammation inhibitor", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, no. 4, 2014, pages 1222 - 1227, XP028606680, ISSN: 0960-894X, DOI: 10.1016/J.BMCL.2013.12.055 *

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