IT201600122377A1 - Composti di coordinazione e loro formulati, metodi di preparazione ed uso degli stessi come agenti ad azione antiflogistica - Google Patents

Composti di coordinazione e loro formulati, metodi di preparazione ed uso degli stessi come agenti ad azione antiflogistica

Info

Publication number
IT201600122377A1
IT201600122377A1 IT102016000122377A IT201600122377A IT201600122377A1 IT 201600122377 A1 IT201600122377 A1 IT 201600122377A1 IT 102016000122377 A IT102016000122377 A IT 102016000122377A IT 201600122377 A IT201600122377 A IT 201600122377A IT 201600122377 A1 IT201600122377 A1 IT 201600122377A1
Authority
IT
Italy
Prior art keywords
flogistic
coordination
formulas
agents
compounds
Prior art date
Application number
IT102016000122377A
Other languages
English (en)
Inventor
Dolores Fregona
Chiara Nardon
Original Assignee
Dolores Fregona
Chiara Nardon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dolores Fregona, Chiara Nardon filed Critical Dolores Fregona
Priority to IT102016000122377A priority Critical patent/IT201600122377A1/it
Priority to PCT/IB2017/057592 priority patent/WO2018100560A1/en
Publication of IT201600122377A1 publication Critical patent/IT201600122377A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/12Gold compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT102016000122377A 2016-12-02 2016-12-02 Composti di coordinazione e loro formulati, metodi di preparazione ed uso degli stessi come agenti ad azione antiflogistica IT201600122377A1 (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT102016000122377A IT201600122377A1 (it) 2016-12-02 2016-12-02 Composti di coordinazione e loro formulati, metodi di preparazione ed uso degli stessi come agenti ad azione antiflogistica
PCT/IB2017/057592 WO2018100560A1 (en) 2016-12-02 2017-12-02 Coordination compounds and formulations, preparation methods and use thereof as antiphlogistic agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102016000122377A IT201600122377A1 (it) 2016-12-02 2016-12-02 Composti di coordinazione e loro formulati, metodi di preparazione ed uso degli stessi come agenti ad azione antiflogistica

Publications (1)

Publication Number Publication Date
IT201600122377A1 true IT201600122377A1 (it) 2018-06-02

Family

ID=58455457

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102016000122377A IT201600122377A1 (it) 2016-12-02 2016-12-02 Composti di coordinazione e loro formulati, metodi di preparazione ed uso degli stessi come agenti ad azione antiflogistica

Country Status (2)

Country Link
IT (1) IT201600122377A1 (it)
WO (1) WO2018100560A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11045553B2 (en) 2017-12-18 2021-06-29 Auburn University Method for preparing stabilized metal ion ligand nanocomplex and compositions thereof
CN110408047B (zh) * 2019-08-29 2020-06-23 中南大学 纳米配位聚合物及其制备方法和应用

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
ALEX FRAGOSO ET AL: "Influence of Electrostatic Interactions and Hydrogen Bonding on the Activity of Cyclodextrin-based Superoxide Dismutase Models", SUPRAMOLECULAR CHEMISTRY., vol. 13, no. 5, 1 September 2001 (2001-09-01), US, pages 619 - 625, XP055374831, ISSN: 1061-0278, DOI: 10.1080/10610270108039795 *
BENIGNO MACIAS ET AL: "Copper complexes with dithiocarbamates derived from natural occurring amino acids. Crystal and molecular structure of [Cu(en)(EtOH)(H 2O) 3][Cu(dtc-pro) 2]", POLYHEDRON, 1 January 2002 (2002-01-01), pages 1899 - 1904, XP055366149, Retrieved from the Internet <URL:http://ac.els-cdn.com/S0277538702010987/1-s2.0-S0277538702010987-main.pdf?_tid=54114b32-2654-11e7-97ae-00000aab0f27&acdnat=1492753108_d69a0caee314a2d85d15d9530fde3868> DOI: 10.1016/S0277-5387(02)01098-7 *
CHIARA NARDON ET AL: "Gold Complexes for Therapeutic Purposes: an Updated Patent Review (2010-2015)", CURRENT MEDICINAL CHEMISTRY : THE NEW INTERNATIONAL JOURNAL FOR TIMELY IN-DEPTH REVIEWS IN MEDICINAL CHEMISTRY, vol. 23, no. 29, 1 August 2016 (2016-08-01), NL, pages 3374 - 3403, XP055366360, ISSN: 0929-8673, DOI: 10.2174/0929867323666160504103843 *
DIAZ A ET AL: "Interactions of nitric ocide with copper (II) dithiocarbamates in aqueous solution", JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER INC, US, no. 95, 1 January 2003 (2003-01-01), pages 283 - 290, XP002335489, ISSN: 0162-0134, DOI: 10.1016/S0162-0134(03)00126-0 *
FRAGOSO ALEX ET AL: "Esterase activity of cyclodextrin dithiocarbamates", TETRAHEDRON LETTERS, vol. 45, no. 21, 2004, pages 4069 - 4071, XP085010797, ISSN: 0040-4039, DOI: 10.1016/J.TETLET.2004.03.156 *
LUCA RONCONI ET AL: "Latest Insights into the Anticancer Activity of Gold(III)-Dithiocarbamato Complexes", ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBLISHERS LTD, NL, vol. 10, no. 4, 1 January 2010 (2010-01-01), pages 283 - 292, XP008184285, ISSN: 1871-5206, DOI: 10.2174/187152010791162298 *
MORELLE NEGOM KOUODOM ET AL: "Rational design of gold(III)-dithiocarbamato peptidomimetics for the targeted anticancer chemotherapy", JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 117, 1 December 2012 (2012-12-01), US, pages 248 - 260, XP055366138, ISSN: 0162-0134, DOI: 10.1016/j.jinorgbio.2012.07.001 *
MUHAMMAD ALTAF ET AL: "Synthesis, characterization and in vitro cytotoxicity of gold(III) dialkyl/diaryldithiocarbamato complexes", RSC ADVANCES: AN INTERNATIONAL JOURNAL TO FURTHER THE CHEMICAL SCIENCES, vol. 5, no. 99, 1 January 2015 (2015-01-01), GB, pages 81599 - 81607, XP055366145, ISSN: 2046-2069, DOI: 10.1039/C5RA15123F *
ROBERTO CAO ET AL: "Gold Nanoparticles Enhancing Dismutation of Superoxide Radical by Its Bis(dithiocarbamato)copper(II) Shell", INORGANIC CHEMISTRY, vol. 50, no. 11, 6 June 2011 (2011-06-06), EASTON, US, pages 4705 - 4712, XP055366148, ISSN: 0020-1669, DOI: 10.1021/ic101770h *
SUZUKI Y ET AL: "The origin of an EPR signal observed in dithiocarbamate-loaded tissues - Copper(II)-dithiocarbamate complexes account for the narrow hyperfine lines", BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - GENERAL SUBJECTS, ELSEVIER, AMSTERDAM, NL, vol. 1335, no. 3, 6 June 1997 (1997-06-06), pages 242 - 245, XP004275984, ISSN: 0304-4165, DOI: 10.1016/S0304-4165(97)00027-5 *
VEYSEL T YILMAZ ET AL: "Metal Complexes of Phenylpiperazine-Based Dithiocarbamate Ligands. Synthesis, Characterization, Spectroscopic, Thermal, and Antimicrobial Activity Studies", SYNTHESIS AND REACTIVITY IN INORGANIC AND METALLORGANICCHEMISTRY, MARCEL DEKKER INC. NEW YORK, US, vol. 33, no. 4, 1 January 2003 (2003-01-01), pages 589 - 605, XP008184283, ISSN: 0094-5714, [retrieved on 20070215], DOI: 10.1081/SIM-120020326 *

Also Published As

Publication number Publication date
WO2018100560A1 (en) 2018-06-07

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