IT1402047B1 - Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali - Google Patents

Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali

Info

Publication number
IT1402047B1
IT1402047B1 ITMI2010A001908A ITMI20101908A IT1402047B1 IT 1402047 B1 IT1402047 B1 IT 1402047B1 IT MI2010A001908 A ITMI2010A001908 A IT MI2010A001908A IT MI20101908 A ITMI20101908 A IT MI20101908A IT 1402047 B1 IT1402047 B1 IT 1402047B1
Authority
IT
Italy
Prior art keywords
mexiprostil
treatment
inflammatory diseases
intestinal inflammatory
intestinal
Prior art date
Application number
ITMI2010A001908A
Other languages
English (en)
Italian (it)
Inventor
Alessandro Alessandri
Original Assignee
Cross Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ITMI2010A001908A priority Critical patent/IT1402047B1/it
Application filed by Cross Pharma Sa filed Critical Cross Pharma Sa
Priority to PCT/IB2011/054627 priority patent/WO2012052918A1/en
Priority to BR112013009185A priority patent/BR112013009185A2/pt
Priority to KR1020137011710A priority patent/KR20140008306A/ko
Priority to EP11799304.8A priority patent/EP2629778B1/en
Priority to CA2812891A priority patent/CA2812891A1/en
Priority to US13/880,125 priority patent/US20130202704A1/en
Priority to CN2011800502426A priority patent/CN103167874A/zh
Priority to JP2013534433A priority patent/JP5885749B2/ja
Publication of ITMI20101908A1 publication Critical patent/ITMI20101908A1/it
Application granted granted Critical
Publication of IT1402047B1 publication Critical patent/IT1402047B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/606—Salicylic acid; Derivatives thereof having amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
ITMI2010A001908A 2010-10-19 2010-10-19 Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali IT1402047B1 (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ITMI2010A001908A IT1402047B1 (it) 2010-10-19 2010-10-19 Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali
BR112013009185A BR112013009185A2 (pt) 2010-10-19 2011-10-18 uso de mexiprostil no tratamento de doença inflamatória intestinal e/ou de síndrome do intestino irritável.
KR1020137011710A KR20140008306A (ko) 2010-10-19 2011-10-18 염증성 장 질환 및/또는 과민성 대장 증후군의 치료에서의 멕시프로스틸의 용도
EP11799304.8A EP2629778B1 (en) 2010-10-19 2011-10-18 Use of mexiprostil in the treatment of inflammatory bowel disease and/or of irritable bowel syndrome
PCT/IB2011/054627 WO2012052918A1 (en) 2010-10-19 2011-10-18 Use of mexiprostil in the treatment of inflammatory bowel disease and/or of irritable bowel syndrome
CA2812891A CA2812891A1 (en) 2010-10-19 2011-10-18 Use of mexiprostil in the treatment of inflammatory bowel disease and/or of irritable bowel syndrome
US13/880,125 US20130202704A1 (en) 2010-10-19 2011-10-18 Use of mexiprostil in the treatment of inflammatory bowel disease and/or of irritable bowel syndrome
CN2011800502426A CN103167874A (zh) 2010-10-19 2011-10-18 美昔前列素在炎性肠病和/或肠易激综合症的治疗中的用途
JP2013534433A JP5885749B2 (ja) 2010-10-19 2011-10-18 炎症性腸疾患および／または過敏性腸症候群の治療におけるメキシプロスチルの使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2010A001908A IT1402047B1 (it) 2010-10-19 2010-10-19 Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali

Publications (2)

Publication Number Publication Date
ITMI20101908A1 ITMI20101908A1 (it) 2012-04-20
IT1402047B1 true IT1402047B1 (it) 2013-08-28

Family

ID=43738034

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI2010A001908A IT1402047B1 (it) 2010-10-19 2010-10-19 Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali

Country Status (9)

Country Link
US (1) US20130202704A1 (cg-RX-API-DMAC7.html)
EP (1) EP2629778B1 (cg-RX-API-DMAC7.html)
JP (1) JP5885749B2 (cg-RX-API-DMAC7.html)
KR (1) KR20140008306A (cg-RX-API-DMAC7.html)
CN (1) CN103167874A (cg-RX-API-DMAC7.html)
BR (1) BR112013009185A2 (cg-RX-API-DMAC7.html)
CA (1) CA2812891A1 (cg-RX-API-DMAC7.html)
IT (1) IT1402047B1 (cg-RX-API-DMAC7.html)
WO (1) WO2012052918A1 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8895064B2 (en) 1999-06-14 2014-11-25 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
US10154964B2 (en) 2011-09-07 2018-12-18 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
AU2011248587A1 (en) * 2011-11-09 2013-05-23 Cosmo Technologies Ltd Controlled release and taste masking oral pharmaceutical composition
CN108685929A (zh) * 2012-04-23 2018-10-23 苏坎波公司 用于治疗具有腹泻的肠易激综合征的方法
ES2761636T3 (es) * 2015-05-04 2020-05-20 Univ Leland Stanford Junior Composiciones y métodos para suministro de agentes terapéuticos en el colon

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3704825A1 (de) * 1987-02-16 1988-08-25 Froelich Juergen Prostaglandin e1-derivate als pharmazeutische wirkstoffe und diese verbindungen enthaltende arzneimittel insbesondere zur transkutanen anwendung
US5219885A (en) * 1987-02-16 1993-06-15 Froelich Juergen Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration
ATE82748T1 (de) * 1988-01-28 1992-12-15 Merrell Dow Pharma Verfahren und zwischenprodukte.
US6632451B2 (en) * 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
ITMI991316A1 (it) * 1999-06-14 2000-12-14 Cip Ninety Two 92 S A Composizioni farmaceutiche orali a rilascio modificato di mesalazina
JP4790950B2 (ja) * 1999-06-14 2011-10-12 コスモ・テクノロジーズ・リミテッド 制御放出および味感遮蔽経口医薬組成物
EP1104760B1 (en) * 1999-12-03 2003-03-12 Pfizer Products Inc. Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents
US20050159485A1 (en) * 2002-01-04 2005-07-21 Jost-Price Edward R. Combinations for the treatment of immunoinflammatory disorders and proliferative skin diseases
AU2003292556B2 (en) * 2002-12-27 2009-09-10 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort
US7326698B2 (en) * 2004-07-02 2008-02-05 Allergan, Inc. Prostaglandin analogs

Also Published As

Publication number Publication date
EP2629778A1 (en) 2013-08-28
US20130202704A1 (en) 2013-08-08
CA2812891A1 (en) 2012-04-26
KR20140008306A (ko) 2014-01-21
JP5885749B2 (ja) 2016-03-15
WO2012052918A1 (en) 2012-04-26
CN103167874A (zh) 2013-06-19
BR112013009185A2 (pt) 2016-07-26
ITMI20101908A1 (it) 2012-04-20
JP2013544795A (ja) 2013-12-19
EP2629778B1 (en) 2016-09-21

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