IT1302535B1 - Biomateriali comprendenti derivati dell'acido ialuronico in forma distruttura tridimensionale per la rigenerazione dei tessuti. - Google Patents
Biomateriali comprendenti derivati dell'acido ialuronico in forma distruttura tridimensionale per la rigenerazione dei tessuti.Info
- Publication number
- IT1302535B1 IT1302535B1 ITPD980299A IT1302535B1 IT 1302535 B1 IT1302535 B1 IT 1302535B1 IT PD980299 A ITPD980299 A IT PD980299A IT 1302535 B1 IT1302535 B1 IT 1302535B1
- Authority
- IT
- Italy
- Prior art keywords
- hyaluronic acid
- esterified
- esters
- biocompatible biomaterial
- arylaliphatic
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 11
- 239000012620 biological material Substances 0.000 title abstract 4
- 229920002674 hyaluronan Polymers 0.000 abstract 5
- 229960003160 hyaluronic acid Drugs 0.000 abstract 5
- 150000002148 esters Chemical class 0.000 abstract 4
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical class OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 239000001384 succinic acid Substances 0.000 abstract 2
- 229920001410 Microfiber Polymers 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 238000004132 cross linking Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 239000000835 fiber Substances 0.000 abstract 1
- 150000004676 glycans Polymers 0.000 abstract 1
- 229910001385 heavy metal Chemical class 0.000 abstract 1
- -1 heterocyclic alcohols Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003658 microfiber Substances 0.000 abstract 1
- 150000004804 polysaccharides Polymers 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000001172 regenerating effect Effects 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000006850 spacer group Chemical group 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
Landscapes
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Materials For Medical Uses (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/700,142 US6872819B1 (en) | 1998-05-27 | 1998-05-27 | Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells |
| IT000299 IT1302535B1 (it) | 1998-12-21 | 1998-12-21 | Biomateriali comprendenti derivati dell'acido ialuronico in forma distruttura tridimensionale per la rigenerazione dei tessuti. |
| AU43680/99A AU748303B2 (en) | 1998-05-27 | 1999-05-25 | Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells |
| EP19990926410 EP1085917B1 (en) | 1998-05-27 | 1999-05-25 | Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells |
| PCT/EP1999/003604 WO1999061080A1 (en) | 1998-05-27 | 1999-05-25 | Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells |
| JP2000550539A JP2002516154A (ja) | 1998-05-27 | 1999-05-25 | 細胞成分またはその生成物のない３次元構造のヒアルロン酸誘導体を含有した、組織細胞のインビボ再生用生体材料 |
| DE1999603945 DE69903945T2 (de) | 1998-05-27 | 1999-05-25 | Dreidimensionale biomaterialien, frei von zellulären komponenten und produkten, enthaltend hyaluronsäure-derivate, für die in-vivo regeneration von gewebezellen |
| ES99926410T ES2184460T3 (es) | 1998-05-27 | 1999-05-25 | Uso de derivados del acido hialuronico con estructuras ridimensionales que encierran huecos creados por poros comunicados y/o fibras finas o microfibras enmarañadas, para la elaboracion de biomateriales biocompatibles para la regeneracion in vivo de celulas de tejidos. |
| DK99926410T DK1085917T3 (da) | 1998-05-27 | 1999-05-25 | Biomaterialer indeholdende hyaluronsyrederivater i form af tredimensionale strukturer, som er frie for cellulære komponenter eller produkter deraf, til in vivo-regenerering af vævsceller |
| CA 2332532 CA2332532C (en) | 1998-05-27 | 1999-05-25 | Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells |
| AT99926410T ATE227589T1 (de) | 1998-05-27 | 1999-05-25 | Dreidimensionale biomaterialien, frei von zellulären komponenten und produkten, enthaltend hyaluronsäure-derivate, für die in-vivo regeneration von gewebezellen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000299 IT1302535B1 (it) | 1998-12-21 | 1998-12-21 | Biomateriali comprendenti derivati dell'acido ialuronico in forma distruttura tridimensionale per la rigenerazione dei tessuti. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITPD980299A0 ITPD980299A0 (it) | 1998-12-21 |
| ITPD980299A1 ITPD980299A1 (it) | 2000-06-21 |
| IT1302535B1 true IT1302535B1 (it) | 2000-09-05 |
Family
ID=11392400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000299 IT1302535B1 (it) | 1998-05-27 | 1998-12-21 | Biomateriali comprendenti derivati dell'acido ialuronico in forma distruttura tridimensionale per la rigenerazione dei tessuti. |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1302535B1 (it) |
-
1998
- 1998-12-21 IT IT000299 patent/IT1302535B1/it active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITPD980299A0 (it) | 1998-12-21 |
| ITPD980299A1 (it) | 2000-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |