IT1299201B1 - Fibroblasti modificati geneticamente e loro uso - Google Patents

Fibroblasti modificati geneticamente e loro uso

Info

Publication number
IT1299201B1
IT1299201B1 IT98MI001004A ITMI981004A IT1299201B1 IT 1299201 B1 IT1299201 B1 IT 1299201B1 IT 98MI001004 A IT98MI001004 A IT 98MI001004A IT MI981004 A ITMI981004 A IT MI981004A IT 1299201 B1 IT1299201 B1 IT 1299201B1
Authority
IT
Italy
Prior art keywords
genetically modified
modified fibroblasts
fibroblasts
genetically
expression
Prior art date
Application number
IT98MI001004A
Other languages
English (en)
Inventor
Fulvio Mavilio
Original Assignee
San Raffaele Centro Fond
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by San Raffaele Centro Fond filed Critical San Raffaele Centro Fond
Priority to IT98MI001004A priority Critical patent/IT1299201B1/it
Priority to PCT/EP1999/003075 priority patent/WO1999058646A1/en
Priority to EP99923531A priority patent/EP1084232B1/en
Priority to JP2000548438A priority patent/JP2002514409A/ja
Priority to AU40372/99A priority patent/AU4037299A/en
Priority to AT99923531T priority patent/ATE265526T1/de
Priority to CA002331826A priority patent/CA2331826A1/en
Priority to DE69916829T priority patent/DE69916829D1/de
Publication of ITMI981004A1 publication Critical patent/ITMI981004A1/it
Application granted granted Critical
Publication of IT1299201B1 publication Critical patent/IT1299201B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1307—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT98MI001004A 1998-05-08 1998-05-08 Fibroblasti modificati geneticamente e loro uso IT1299201B1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT98MI001004A IT1299201B1 (it) 1998-05-08 1998-05-08 Fibroblasti modificati geneticamente e loro uso
PCT/EP1999/003075 WO1999058646A1 (en) 1998-05-08 1999-05-05 Genetically-modified fibroblasts and the use thereof
EP99923531A EP1084232B1 (en) 1998-05-08 1999-05-05 Genetically-modified fibroblasts and the use thereof
JP2000548438A JP2002514409A (ja) 1998-05-08 1999-05-05 遺伝的に改変された繊維芽細胞及びその使用
AU40372/99A AU4037299A (en) 1998-05-08 1999-05-05 Genetically-modified fibroblasts and the use thereof
AT99923531T ATE265526T1 (de) 1998-05-08 1999-05-05 Genetisch veränderte fibroblasten und ihre verwendung
CA002331826A CA2331826A1 (en) 1998-05-08 1999-05-05 Genetically-modified fibroblasts and the use thereof
DE69916829T DE69916829D1 (de) 1998-05-08 1999-05-05 Genetisch veränderte fibroblasten und ihre verwendung

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT98MI001004A IT1299201B1 (it) 1998-05-08 1998-05-08 Fibroblasti modificati geneticamente e loro uso

Publications (2)

Publication Number Publication Date
ITMI981004A1 ITMI981004A1 (it) 1999-11-08
IT1299201B1 true IT1299201B1 (it) 2000-02-29

Family

ID=11379982

Family Applications (1)

Application Number Title Priority Date Filing Date
IT98MI001004A IT1299201B1 (it) 1998-05-08 1998-05-08 Fibroblasti modificati geneticamente e loro uso

Country Status (8)

Country Link
EP (1) EP1084232B1 (it)
JP (1) JP2002514409A (it)
AT (1) ATE265526T1 (it)
AU (1) AU4037299A (it)
CA (1) CA2331826A1 (it)
DE (1) DE69916829D1 (it)
IT (1) IT1299201B1 (it)
WO (1) WO1999058646A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6492169B1 (en) 1999-05-18 2002-12-10 Crucell Holland, B.V. Complementing cell lines
EP1157999A1 (en) * 2000-05-24 2001-11-28 Introgene B.V. Methods and means for enhancing skin transplantation using gene delivery vehicles having tropism for primary fibroblasts, as well as other uses thereof
JP2010148440A (ja) * 2008-12-25 2010-07-08 Japan Health Science Foundation 組換えアデノウイルス迅速構築システム
US20200338134A1 (en) * 2019-04-26 2020-10-29 Cleveland State University Muscle treatment method using myod mutant

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219740A (en) * 1987-02-13 1993-06-15 Fred Hutchinson Cancer Research Center Retroviral gene transfer into diploid fibroblasts for gene therapy
WO1995012979A1 (en) * 1993-11-08 1995-05-18 The University Of Southern California Compositions and methods for transduction of cells
GB9419048D0 (en) * 1994-09-20 1994-11-09 Watt Diana J Treatment of muscular disorders
ATE356199T1 (de) * 1996-10-18 2007-03-15 Univ Laval Verfahren zur in vitro vorbehandlung von myoblasten in der transplantation

Also Published As

Publication number Publication date
CA2331826A1 (en) 1999-11-18
EP1084232B1 (en) 2004-04-28
ATE265526T1 (de) 2004-05-15
JP2002514409A (ja) 2002-05-21
AU4037299A (en) 1999-11-29
ITMI981004A1 (it) 1999-11-08
WO1999058646A1 (en) 1999-11-18
DE69916829D1 (de) 2004-06-03
EP1084232A1 (en) 2001-03-21

Similar Documents

Publication Publication Date Title
BR0207775A (pt) Lipossomos anfotéricos métodos para carregamento dos mesmos com ingredientes ativos e sua utilização
DE58906718D1 (de) Kunststeine, verfahren zur herstellung und verwendung derselben.
AU2002343557A1 (en) Substituted aryl 1,4-pyrazine derivatives
KR970001343A (ko) 나프탈렌 유도체,그의 제조 방법,및그의 중간체
DE60010098D1 (de) 28-epirapaloge
MY130489A (en) Substituted aryl 1, 4-pyrazine derivatives
DE59603216D1 (de) Esterquats und ihre Verwendung zur Herstellung von oberflächenaktiven Mitteln, insbesondere zur Haar- und Körperpflege
ATE247099T1 (de) Sulfonamid-derivate, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel
DE3585953D1 (de) Dna-fragmente, expressionsvektoren, proteine, wirte und verfahren zur herstellung der proteine.
DE69901177T2 (de) Platinkomplex, dessen herstellung und dessen therapeutische verwendung
DE69623472D1 (de) Derivate von dolastatin, dreen herstellung un verwendung
EP1616942A3 (en) Patched genes and their use
NO971341D0 (no) Promoter for reseptor tyrosinkinase TIE
ATE405662T1 (de) Verfahren zur herstellung rekombinanter adenovirus-genome
DE69131381T2 (de) Strukturproteine durch künstliche gene
DE69312408T2 (de) Harte, gegen Verschleiss widerstandsfähige Beschichtung und Verfahren zur Herstellung derselben
DE59808444D1 (de) Weichmagnetischer, formbarer verbundwerkstoff und verfahren zu dessen herstellung
DE69626816D1 (de) Verwendung von selegilin zur behandlung von gehörverlust bei säugetieren
IT1299201B1 (it) Fibroblasti modificati geneticamente e loro uso
FI953534A (fi) Menetelmä sellaisten yksölöiden tunnistamiseksi ja hoitamiseksi, joilla on HLA-C-klooni 10/MAGE-1:tä ekspressoivia syöpäsoluja
DE68917154T2 (de) C-terminus-amidierungsenzym-zusammensetzung, verfahren zur herstellung und verwendung.
DE69130845D1 (de) HLA-DR Antigen-Gen, dessen Nukleotidsequenz und Verwendung
TW200503717A (en) Substituted 1,4-pyrazine derivatives
FI960706A0 (fi) Uusi proteiini ja menetelmiä proteiinin valmistamiseksi
DE69611303T2 (de) Benzolsulfonamidderivate, ihre herstellung und ihre therapeutische verwendung

Legal Events

Date Code Title Description
0001 Granted