IT1292885B1 - Processo per la produzione degli isomeri (r) ed (s)- alfa -metil-3- (trifluorometil)benzene-etanamina. - Google Patents

Processo per la produzione degli isomeri (r) ed (s)- alfa -metil-3- (trifluorometil)benzene-etanamina.

Info

Publication number
IT1292885B1
IT1292885B1 IT97BO000252A ITBO970252A IT1292885B1 IT 1292885 B1 IT1292885 B1 IT 1292885B1 IT 97BO000252 A IT97BO000252 A IT 97BO000252A IT BO970252 A ITBO970252 A IT BO970252A IT 1292885 B1 IT1292885 B1 IT 1292885B1
Authority
IT
Italy
Prior art keywords
ethanamine
isomers
trifluoromethyl
benzene
alpha
Prior art date
Application number
IT97BO000252A
Other languages
English (en)
Inventor
Vincenzo Cannata
Barbara Galbiati
Tiziano Ferrario
Original Assignee
Alfa Chem Ital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Chem Ital filed Critical Alfa Chem Ital
Publication of ITBO970252A0 publication Critical patent/ITBO970252A0/it
Priority to IT97BO000252A priority Critical patent/IT1292885B1/it
Priority to EP97113220A priority patent/EP0875498A3/en
Priority to US08/904,338 priority patent/US5808156A/en
Priority to CA002212203A priority patent/CA2212203A1/en
Priority to HU9701364A priority patent/HUP9701364A3/hu
Priority to TW086111229A priority patent/TW389748B/zh
Priority to AU33220/97A priority patent/AU3322097A/en
Priority to KR1019970037964A priority patent/KR19980079310A/ko
Priority to ZA9708203A priority patent/ZA978203B/xx
Priority to PL97322542A priority patent/PL322542A1/xx
Priority to ARP970105548A priority patent/AR008700A1/es
Priority to MXPA/A/1997/009301A priority patent/MXPA97009301A/xx
Priority to JP10109697A priority patent/JPH10330330A/ja
Publication of ITBO970252A1 publication Critical patent/ITBO970252A1/it
Application granted granted Critical
Publication of IT1292885B1 publication Critical patent/IT1292885B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
    • C07C209/26—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT97BO000252A 1997-04-28 1997-04-28 Processo per la produzione degli isomeri (r) ed (s)- alfa -metil-3- (trifluorometil)benzene-etanamina. IT1292885B1 (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT97BO000252A IT1292885B1 (it) 1997-04-28 1997-04-28 Processo per la produzione degli isomeri (r) ed (s)- alfa -metil-3- (trifluorometil)benzene-etanamina.
EP97113220A EP0875498A3 (en) 1997-04-28 1997-07-31 Process for the production of the isomers (R) and (S)-Alpha-methyl-3-(trifluoromethyl)benzeneethanamine
US08/904,338 US5808156A (en) 1997-04-28 1997-07-31 Process for the production of the isomers (R) and (S)-α-methyl-3(trifluoromethyl)benzeneethanamine
CA002212203A CA2212203A1 (en) 1997-04-28 1997-08-01 Process for the production of the isomers (r) and (s)-alpha-methyl-3-(trifluoromethyl)benzeneethanamine
HU9701364A HUP9701364A3 (en) 1997-04-28 1997-08-06 Procedure for making (r) and (s) isomers of alfa-metil-2-[3-(trifluor-metil)-fenil]-etil-amin and the isomers and salts
TW086111229A TW389748B (en) 1997-04-28 1997-08-06 Process for the production of the isomers (R) and (S) -<alpha>-methyl -3 - (trifluoromethyl) benzeneethanamine
AU33220/97A AU3322097A (en) 1997-04-28 1997-08-07 Process for the production of the isomers(R) and (S)-alpha-methyl-3(trifluoromethyl)benzeneethanamine
KR1019970037964A KR19980079310A (ko) 1997-04-28 1997-08-08 (r) 및 (s)-알파-메틸-3(트리플로로메틸)벤젠에탄아민의 제조방법
ZA9708203A ZA978203B (en) 1997-04-28 1997-09-11 Process for the production of the isomers (R) and (S)-alpha-methyl-3-(trifluoromethyl) benzeneethanamine.
PL97322542A PL322542A1 (en) 1997-04-28 1997-10-10 Method of obtaining isomers of (r)-and (s)-alpha-methyl-3-(trifluoromethyl)benzene dimethylamine
ARP970105548A AR008700A1 (es) 1997-04-28 1997-11-26 Proceso para la produccion de losisomeros (r) y (s)--metil-3- -(trifluorometil) bencenoetanamina y los intermediarios en dicho proceso.
MXPA/A/1997/009301A MXPA97009301A (en) 1997-04-29 1997-12-01 Process for the production of the isomers (r) and (s) alpha-methyl-3 (trifluoromethyl) bencenetanam
JP10109697A JPH10330330A (ja) 1997-04-28 1998-04-20 α−メチル−３−（トリフルオロメチル）ベンゼンエタンアミンの（Ｒ）または（Ｓ）異性体の製造法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97BO000252A IT1292885B1 (it) 1997-04-28 1997-04-28 Processo per la produzione degli isomeri (r) ed (s)- alfa -metil-3- (trifluorometil)benzene-etanamina.

Publications (3)

Publication Number Publication Date
ITBO970252A0 ITBO970252A0 (it) 1997-04-28
ITBO970252A1 ITBO970252A1 (it) 1998-10-29
IT1292885B1 true IT1292885B1 (it) 1999-02-11

Family

ID=11342228

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97BO000252A IT1292885B1 (it) 1997-04-28 1997-04-28 Processo per la produzione degli isomeri (r) ed (s)- alfa -metil-3- (trifluorometil)benzene-etanamina.

Country Status (12)

Country Link
US (1) US5808156A (it)
EP (1) EP0875498A3 (it)
JP (1) JPH10330330A (it)
KR (1) KR19980079310A (it)
AR (1) AR008700A1 (it)
AU (1) AU3322097A (it)
CA (1) CA2212203A1 (it)
HU (1) HUP9701364A3 (it)
IT (1) IT1292885B1 (it)
PL (1) PL322542A1 (it)
TW (1) TW389748B (it)
ZA (1) ZA978203B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009080512A1 (de) * 2007-12-21 2009-07-02 Basf Se Einstufige reduktive aminierung
US9549909B2 (en) 2013-05-03 2017-01-24 The Katholieke Universiteit Leuven Method for the treatment of dravet syndrome
KR102245345B1 (ko) 2014-09-29 2021-04-28 조게닉스 인터내셔널 리미티드 의약품 배포 제어를 위한 제어 시스템
CA3007673A1 (en) 2015-12-22 2017-06-29 Zogenix International Limited Metabolism resistant fenfluramine analogs and methods of using the same
SI4293009T1 (sl) 2015-12-22 2025-09-30 Zogenix International Limited Sestavine fenfluramina in postopki za njihovo pripravo
AU2017315273B2 (en) 2016-08-24 2021-04-29 Zogenix International Limited Formulation for inhibiting formation of 5-HT 2B agonists and methods of using same
US10682317B2 (en) 2017-09-26 2020-06-16 Zogenix International Limited Ketogenic diet compatible fenfluramine formulation
WO2019216919A1 (en) 2018-05-11 2019-11-14 Zogenix International Limited Compositions and methods for treating seizure-induced sudden death
WO2020105005A1 (en) 2018-11-19 2020-05-28 Zogenix International Limited Methods of treating rett syndrome using fenfluramine
US11612574B2 (en) 2020-07-17 2023-03-28 Zogenix International Limited Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR104F (it) * 1960-11-05
GB1413078A (en) * 1973-07-27 1975-11-05 Beecham Group Ltd Process for the production of plus-norfenfluramine and plus-fenfluramine and salts thereof
GB1413070A (en) * 1973-07-27 1975-11-05 Beecham Group Ltd Process for the production of - norfenfluramine and - fenfluramine and salts thereof
DE3819438A1 (de) * 1987-06-30 1989-01-19 Basf Ag Verfahren zur herstellung von optisch aktiven 1-arylethylaminen

Also Published As

Publication number Publication date
ITBO970252A0 (it) 1997-04-28
HUP9701364A3 (en) 1999-07-28
US5808156A (en) 1998-09-15
ITBO970252A1 (it) 1998-10-29
PL322542A1 (en) 1998-11-09
KR19980079310A (ko) 1998-11-25
HU9701364D0 (en) 1997-09-29
EP0875498A2 (en) 1998-11-04
AR008700A1 (es) 2000-02-09
JPH10330330A (ja) 1998-12-15
ZA978203B (en) 1998-04-29
CA2212203A1 (en) 1998-10-29
HUP9701364A2 (hu) 1999-04-28
AU3322097A (en) 1998-11-05
MX9709301A (es) 1998-10-31
EP0875498A3 (en) 2000-07-26
TW389748B (en) 2000-05-11

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Legal Events

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