IT1271426B - Procedimento di produzione del sale trisodico ottaidrato cristallino del fruttosio 1,6-difosfato (fdpna3h*8h20) - Google Patents

Procedimento di produzione del sale trisodico ottaidrato cristallino del fruttosio 1,6-difosfato (fdpna3h*8h20)

Info

Publication number
IT1271426B
IT1271426B ITMI930029A ITMI930029A IT1271426B IT 1271426 B IT1271426 B IT 1271426B IT MI930029 A ITMI930029 A IT MI930029A IT MI930029 A ITMI930029 A IT MI930029A IT 1271426 B IT1271426 B IT 1271426B
Authority
IT
Italy
Prior art keywords
diphosphate
trisode
fdpna3h
production process
crystalline fructose
Prior art date
Application number
ITMI930029A
Other languages
English (en)
Inventor
Stefano Ceccarelli
Francesco Magnante
Sergio Zanarella
Original Assignee
Foscama Biomed Chim Farma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foscama Biomed Chim Farma filed Critical Foscama Biomed Chim Farma
Priority to ITMI930029A priority Critical patent/IT1271426B/it
Publication of ITMI930029A0 publication Critical patent/ITMI930029A0/it
Priority to DE69406809T priority patent/DE69406809T2/de
Priority to EP94100167A priority patent/EP0606853B1/en
Priority to CN94100631A priority patent/CN1034018C/zh
Publication of ITMI930029A1 publication Critical patent/ITMI930029A1/it
Priority to US08/510,871 priority patent/US5571906A/en
Application granted granted Critical
Publication of IT1271426B publication Critical patent/IT1271426B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Si descrive un procedimento per la preparazione del sale trisodico ottaidrato del fruttosio 1,6-difosfato partendo da una soluzione acquosa a pH acido di D-fruttosio 1,6-difosfato, a cui si aggiunge un'opportuna quantità di acetone; si cristallizza e si filtra la miscela reazionale per ottenere il prodotto desiderato, che viene infine essiccato.
ITMI930029A 1993-01-13 1993-01-13 Procedimento di produzione del sale trisodico ottaidrato cristallino del fruttosio 1,6-difosfato (fdpna3h*8h20) IT1271426B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ITMI930029A IT1271426B (it) 1993-01-13 1993-01-13 Procedimento di produzione del sale trisodico ottaidrato cristallino del fruttosio 1,6-difosfato (fdpna3h*8h20)
DE69406809T DE69406809T2 (de) 1993-01-13 1994-01-07 Neues Verfahren zur Gewinnung des Oktahydro-Trinatriumsalzes von Fructose-1,6-diphosphat (FdPNa3H*8H2O) in einer kristallinen Form
EP94100167A EP0606853B1 (en) 1993-01-13 1994-01-07 New process for obtaining octahydro trisodium salt of fructose 1,6-diphosphate (FdPNa3H*8H20) in a crystalline form
CN94100631A CN1034018C (zh) 1993-01-13 1994-01-13 生产晶形果糖-1，6-二磷酸八水三钠盐的新方法
US08/510,871 US5571906A (en) 1993-01-13 1995-08-03 Process for obtaining octahydro trisodium salt of fructose 1,6-diphosphate (FdPNa3H*8H2O) in crystalline form

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI930029A IT1271426B (it) 1993-01-13 1993-01-13 Procedimento di produzione del sale trisodico ottaidrato cristallino del fruttosio 1,6-difosfato (fdpna3h*8h20)

Publications (3)

Publication Number Publication Date
ITMI930029A0 ITMI930029A0 (it) 1993-01-13
ITMI930029A1 ITMI930029A1 (it) 1994-07-13
IT1271426B true IT1271426B (it) 1997-05-28

Family

ID=11364622

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI930029A IT1271426B (it) 1993-01-13 1993-01-13 Procedimento di produzione del sale trisodico ottaidrato cristallino del fruttosio 1,6-difosfato (fdpna3h*8h20)

Country Status (5)

Country Link
US (1) US5571906A (it)
EP (1) EP0606853B1 (it)
CN (1) CN1034018C (it)
DE (1) DE69406809T2 (it)
IT (1) IT1271426B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3579926B2 (ja) * 1994-08-25 2004-10-20 ソニー株式会社 デジタルビデオ信号の再生方法及び再生装置
US5731291A (en) * 1996-05-08 1998-03-24 Cypros Pharmaceutical Corp. Partially lyophilized fructose-1,6-diphosphate (FDP) for injection into humans
US5944020A (en) * 1997-02-25 1999-08-31 Cypros Pharmaceutical Corp. Use of fructose-1 6-diphosphate as an inotrope drug after cardiopulmonary bypass surgery
CN1057299C (zh) * 1998-08-28 2000-10-11 重庆医科大学 D-果糖-1,6-二磷酸钠镁、其制备方法和在制备药品上的用途
CN106810583B (zh) * 2016-12-30 2019-04-02 珠海同源药业有限公司 一种果糖二磷酸钠化合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3066135A (en) * 1959-10-03 1962-11-27 Biomedica Int Process for the preparation of hexose alkali metal salts of hexose diphosphate from insoluble salts thereof

Also Published As

Publication number Publication date
US5571906A (en) 1996-11-05
DE69406809T2 (de) 1998-03-19
EP0606853A1 (en) 1994-07-20
DE69406809D1 (de) 1998-01-02
ITMI930029A1 (it) 1994-07-13
ITMI930029A0 (it) 1993-01-13
EP0606853B1 (en) 1997-11-19
CN1100726A (zh) 1995-03-29
CN1034018C (zh) 1997-02-12

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970124