IT1270825B - Process for the preparation of phosphatidyl lipo- nucleotides - Google Patents
Process for the preparation of phosphatidyl lipo- nucleotidesInfo
- Publication number
- IT1270825B IT1270825B ITMI931860A ITMI931860A IT1270825B IT 1270825 B IT1270825 B IT 1270825B IT MI931860 A ITMI931860 A IT MI931860A IT MI931860 A ITMI931860 A IT MI931860A IT 1270825 B IT1270825 B IT 1270825B
- Authority
- IT
- Italy
- Prior art keywords
- lipo
- phosphatidyl
- nucleotides
- preparation
- chlorophosphoro
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000002773 nucleotide Substances 0.000 title abstract 3
- 125000001095 phosphatidyl group Chemical group 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- WNXJIVFYUVYPPR-UHFFFAOYSA-N 1,3-dioxolane Chemical compound C1COCO1 WNXJIVFYUVYPPR-UHFFFAOYSA-N 0.000 abstract 1
- 102000004882 Lipase Human genes 0.000 abstract 1
- 108090001060 Lipase Proteins 0.000 abstract 1
- IDNJBJJSMDYULP-UHFFFAOYSA-N chlorophosphonamidous acid Chemical compound NP(O)Cl IDNJBJJSMDYULP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000005809 transesterification reaction Methods 0.000 abstract 1
Abstract
Process for the preparation of phosphatidyl lipo- nucleotides which comprises the condensation of a 1,3- dioxolan with a chlorophosphoro amidite to yield a compound which is converted into glyceryl nucleotide which yields the desired phosphatidyl lipo-nucleotides by transesterification in the presence of a lipase enzyme in organic solvent, and the invention also relates to the intermediate obtained by that process.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI931860A IT1270825B (en) | 1993-08-27 | 1993-08-27 | Process for the preparation of phosphatidyl lipo- nucleotides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI931860A IT1270825B (en) | 1993-08-27 | 1993-08-27 | Process for the preparation of phosphatidyl lipo- nucleotides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI931860A0 ITMI931860A0 (en) | 1993-08-27 |
| ITMI931860A1 ITMI931860A1 (en) | 1995-02-28 |
| IT1270825B true IT1270825B (en) | 1997-05-13 |
Family
ID=11366835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI931860A IT1270825B (en) | 1993-08-27 | 1993-08-27 | Process for the preparation of phosphatidyl lipo- nucleotides |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1270825B (en) |
-
1993
- 1993-08-27 IT ITMI931860A patent/IT1270825B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI931860A0 (en) | 1993-08-27 |
| ITMI931860A1 (en) | 1995-02-28 |
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Legal Events
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|---|---|---|---|
| 0001 | Granted |