IT1266782B1 - Apparecchiatura e procedimento per la preparazione di microcapsule polimeriche contenenti cellule produttrici di ormoni - Google Patents

Apparecchiatura e procedimento per la preparazione di microcapsule polimeriche contenenti cellule produttrici di ormoni

Info

Publication number
IT1266782B1
IT1266782B1 IT93MI002371A ITMI932371A IT1266782B1 IT 1266782 B1 IT1266782 B1 IT 1266782B1 IT 93MI002371 A IT93MI002371 A IT 93MI002371A IT MI932371 A ITMI932371 A IT MI932371A IT 1266782 B1 IT1266782 B1 IT 1266782B1
Authority
IT
Italy
Prior art keywords
microcaps
polymer
procedure
preparation
equipment
Prior art date
Application number
IT93MI002371A
Other languages
English (en)
Inventor
Giovanni Brotzu
Original Assignee
Giovanni Brotzu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giovanni Brotzu filed Critical Giovanni Brotzu
Priority to IT93MI002371A priority Critical patent/IT1266782B1/it
Publication of ITMI932371A0 publication Critical patent/ITMI932371A0/it
Priority to EP94117403A priority patent/EP0651996A1/en
Priority to CA002135374A priority patent/CA2135374A1/en
Publication of ITMI932371A1 publication Critical patent/ITMI932371A1/it
Application granted granted Critical
Publication of IT1266782B1 publication Critical patent/IT1266782B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT93MI002371A 1993-11-08 1993-11-08 Apparecchiatura e procedimento per la preparazione di microcapsule polimeriche contenenti cellule produttrici di ormoni IT1266782B1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT93MI002371A IT1266782B1 (it) 1993-11-08 1993-11-08 Apparecchiatura e procedimento per la preparazione di microcapsule polimeriche contenenti cellule produttrici di ormoni
EP94117403A EP0651996A1 (en) 1993-11-08 1994-11-04 Equipment and process for the preparation of polymeric microcapsules containing cells producing hormones
CA002135374A CA2135374A1 (en) 1993-11-08 1994-11-08 Equipment and process for the preparation of polymeric microcapsules containing cells producing hormones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI002371A IT1266782B1 (it) 1993-11-08 1993-11-08 Apparecchiatura e procedimento per la preparazione di microcapsule polimeriche contenenti cellule produttrici di ormoni

Publications (3)

Publication Number Publication Date
ITMI932371A0 ITMI932371A0 (it) 1993-11-08
ITMI932371A1 ITMI932371A1 (it) 1995-05-08
IT1266782B1 true IT1266782B1 (it) 1997-01-21

Family

ID=11367168

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI002371A IT1266782B1 (it) 1993-11-08 1993-11-08 Apparecchiatura e procedimento per la preparazione di microcapsule polimeriche contenenti cellule produttrici di ormoni

Country Status (3)

Country Link
EP (1) EP0651996A1 (it)
CA (1) CA2135374A1 (it)
IT (1) IT1266782B1 (it)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3448268C2 (en) * 1984-09-07 1990-02-22 Joachim Prof. Dr. Klein Process for the production of a biocatalyst
US4670035A (en) * 1985-07-02 1987-06-02 California Institute Of Technology Method and apparatus for generating microshells of refractory materials
IL79052A0 (en) * 1986-06-06 1986-11-30 Univ Ramot Device and process for production of alginate-shell beads containing biologically active material
JPS63177791A (ja) * 1987-01-16 1988-07-21 Kibun Kk 固定化酵素又は固定化微生物の製造法
WO1991009119A1 (en) * 1989-12-13 1991-06-27 Trancel Corporation Improved alginate microcapsules, methods of making and using same

Also Published As

Publication number Publication date
EP0651996A1 (en) 1995-05-10
ITMI932371A0 (it) 1993-11-08
ITMI932371A1 (it) 1995-05-08
CA2135374A1 (en) 1995-05-09

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