IT1256629B - PROCESS FOR THE SYNTHESIS OF CEFAMI - Google Patents
PROCESS FOR THE SYNTHESIS OF CEFAMIInfo
- Publication number
- IT1256629B IT1256629B ITMI922793A ITMI922793A IT1256629B IT 1256629 B IT1256629 B IT 1256629B IT MI922793 A ITMI922793 A IT MI922793A IT MI922793 A ITMI922793 A IT MI922793A IT 1256629 B IT1256629 B IT 1256629B
- Authority
- IT
- Italy
- Prior art keywords
- formula
- compound
- cefami
- synthesis
- lactams
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229910001882 dioxygen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000003999 initiator Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Un processo per la preparazione di un composto di formula (I): (FORMULA I) nella quale ciascuno degli R1 R2, indipendentemente uno dall'altro, è idrogeno o un residuo organico, comprende le operazioni di far reagire un composto di formula (II): (FORMULA II) nella quale R1 e R2 sono come definiti precedentemente, con un iniziatore radicalico, in presenza di ossigeno molecolare, tipicamente O2 puro o aria. I composti di formula (I) sono intermedi utili per la produzione di molti antibiotici ?-lattamici utili.A process for the preparation of a compound of formula (I): (FORMULA I) in which each of the R1 R2, independently of each other, is hydrogen or an organic residue, includes the operations of reacting a compound of formula (II ): (FORMULA II) in which R1 and R2 are as previously defined, with a radical initiator, in the presence of molecular oxygen, typically pure O2 or air. Are the compounds of formula (I) useful intermediates for the production of many useful antibiotics? -Lactams.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9126342A GB2262281B (en) | 1991-12-11 | 1991-12-11 | Process for the synthesis of cephams |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI922793A0 ITMI922793A0 (en) | 1992-12-09 |
ITMI922793A1 ITMI922793A1 (en) | 1994-06-09 |
IT1256629B true IT1256629B (en) | 1995-12-12 |
Family
ID=10706101
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI922793A IT1256629B (en) | 1991-12-11 | 1992-12-09 | PROCESS FOR THE SYNTHESIS OF CEFAMI |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPH05247057A (en) |
DE (1) | DE4241917A1 (en) |
GB (1) | GB2262281B (en) |
IT (1) | IT1256629B (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS563877B2 (en) * | 1974-02-16 | 1981-01-27 | ||
GB1531586A (en) * | 1976-11-08 | 1978-11-08 | Teijin Ltd | Cephalosporanic acid derivatives and their preparation |
-
1991
- 1991-12-11 GB GB9126342A patent/GB2262281B/en not_active Expired - Fee Related
-
1992
- 1992-12-09 JP JP4329640A patent/JPH05247057A/en active Pending
- 1992-12-09 IT ITMI922793A patent/IT1256629B/en active IP Right Grant
- 1992-12-11 DE DE4241917A patent/DE4241917A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ITMI922793A1 (en) | 1994-06-09 |
ITMI922793A0 (en) | 1992-12-09 |
GB2262281B (en) | 1995-10-25 |
GB9126342D0 (en) | 1992-02-12 |
DE4241917A1 (en) | 1993-06-17 |
GB2262281A (en) | 1993-06-16 |
JPH05247057A (en) | 1993-09-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19951127 |