IT1254706B - Uso terapeutico del ganglioside gm1 nel trattamento del danno al midollo spinale - Google Patents
Uso terapeutico del ganglioside gm1 nel trattamento del danno al midollo spinaleInfo
- Publication number
- IT1254706B IT1254706B ITPD910234A ITPD910234A IT1254706B IT 1254706 B IT1254706 B IT 1254706B IT PD910234 A ITPD910234 A IT PD910234A IT PD910234 A ITPD910234 A IT PD910234A IT 1254706 B IT1254706 B IT 1254706B
- Authority
- IT
- Italy
- Prior art keywords
- ganglioside
- spinal cord
- treatment
- damage
- therapeutic use
- Prior art date
Links
- QPJBWNIQKHGLAU-IQZHVAEDSA-N ganglioside GM1 Chemical compound O[C@@H]1[C@@H](O)[C@H](OC[C@H](NC(=O)CCCCCCCCCCCCCCCCC)[C@H](O)\C=C\CCCCCCCCCCCCC)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@]2(O[C@H]([C@H](NC(C)=O)[C@@H](O)C2)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)[C@@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](CO)O1 QPJBWNIQKHGLAU-IQZHVAEDSA-N 0.000 title abstract 3
- 210000000278 spinal cord Anatomy 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title 1
- VHRSUDSXCMQTMA-PJHHCJLFSA-N 6alpha-methylprednisolone Chemical compound C([C@@]12C)=CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C)[C@@](O)(C(=O)CO)CC[C@H]21 VHRSUDSXCMQTMA-PJHHCJLFSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960004584 methylprednisolone Drugs 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
La presente invenzione si riferisce ad un metodo per il recupero neurologico di pazienti con danno al midollo spinale tramite la somministrazione del ganglioside GM1. Un ulteriore oggetto della presente invenzione è una terapia associata per il trattamento del danno al midollo spinale, rappresentata dalla somministrazione del ganglioside GM1 e dei farmaci presunti attivi per il sopracitato trattamento, ed in modo preferenziale del metilprednisolone.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITPD910234A IT1254706B (it) | 1991-12-23 | 1991-12-23 | Uso terapeutico del ganglioside gm1 nel trattamento del danno al midollo spinale |
| EP91122324A EP0548406A1 (en) | 1991-12-23 | 1991-12-27 | Therapeutic use of ganglioside GM1 in the treatment of spinal cord injury |
| US10/125,810 US6620793B2 (en) | 1991-12-23 | 2002-04-18 | Therapeutic use of ganglioside GM1 in the treatment of spinal cord injury |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITPD910234A IT1254706B (it) | 1991-12-23 | 1991-12-23 | Uso terapeutico del ganglioside gm1 nel trattamento del danno al midollo spinale |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITPD910234A0 ITPD910234A0 (it) | 1991-12-23 |
| ITPD910234A1 ITPD910234A1 (it) | 1993-06-23 |
| IT1254706B true IT1254706B (it) | 1995-10-09 |
Family
ID=11389754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITPD910234A IT1254706B (it) | 1991-12-23 | 1991-12-23 | Uso terapeutico del ganglioside gm1 nel trattamento del danno al midollo spinale |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US6620793B2 (it) |
| EP (1) | EP0548406A1 (it) |
| IT (1) | IT1254706B (it) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1258310B (it) * | 1992-04-10 | 1996-02-22 | Fidia Spa | Composizioni farmaceutiche comprendenti derivati monosialogangliosidici atte al trattamento del danno al midollo spinale. |
| US6888807B2 (en) * | 2002-06-10 | 2005-05-03 | Ipr Licensing, Inc. | Applying session services based on packet flows |
| US20070004625A1 (en) * | 2005-06-30 | 2007-01-04 | Li Liang-Man | Use of complement inhibitory proteins to treat spinal cord injury |
| EP1738763A1 (en) | 2005-06-30 | 2007-01-03 | AVANT Immunotherapeutics, Inc. | Use of complement inhibitory proteins to treat spinal cord injury |
| US7943750B2 (en) * | 2007-06-18 | 2011-05-17 | Laboratoire Medidom S.A. | Process for obtaining pure monosialoganglioside GM1 for medical use |
| ES2750308T3 (es) * | 2015-05-22 | 2020-03-25 | Bioiberica | Proceso para preparar un extracto de cerebro de un animal |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1199116B (it) | 1984-07-03 | 1988-12-30 | Fidia Farmaceutici | Derivati di gangliosidi |
| IT1182209B (it) | 1985-02-18 | 1987-09-30 | Fidia Farmaceutici | Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali |
| US4851521A (en) * | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
| SE8703625D0 (sv) | 1987-09-18 | 1987-09-18 | Kabivitrum Ab | New medical use |
-
1991
- 1991-12-23 IT ITPD910234A patent/IT1254706B/it active IP Right Grant
- 1991-12-27 EP EP91122324A patent/EP0548406A1/en not_active Withdrawn
-
2002
- 2002-04-18 US US10/125,810 patent/US6620793B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20030153517A1 (en) | 2003-08-14 |
| ITPD910234A1 (it) | 1993-06-23 |
| EP0548406A1 (en) | 1993-06-30 |
| ITPD910234A0 (it) | 1991-12-23 |
| US6620793B2 (en) | 2003-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19981002 |