IT1254309B - GENETIC SEQUENCES FOR 90K ANTIGEN ASSOCIATED WITH CANCER. - Google Patents

GENETIC SEQUENCES FOR 90K ANTIGEN ASSOCIATED WITH CANCER.

Info

Publication number
IT1254309B
IT1254309B ITRM920100A ITRM920100A IT1254309B IT 1254309 B IT1254309 B IT 1254309B IT RM920100 A ITRM920100 A IT RM920100A IT RM920100 A ITRM920100 A IT RM920100A IT 1254309 B IT1254309 B IT 1254309B
Authority
IT
Italy
Prior art keywords
antigen
cancer
antigen associated
genetic sequences
molecular weight
Prior art date
Application number
ITRM920100A
Other languages
Italian (it)
Inventor
Stefano Iacobelli
Clara Natoli
Original Assignee
Uni Degli Studi G D Annunzio C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uni Degli Studi G D Annunzio C filed Critical Uni Degli Studi G D Annunzio C
Priority to ITRM920100A priority Critical patent/IT1254309B/en
Publication of ITRM920100A0 publication Critical patent/ITRM920100A0/en
Priority to PCT/EP1993/000382 priority patent/WO1993016180A2/en
Priority to AU34978/93A priority patent/AU3497893A/en
Priority to ZA931101A priority patent/ZA931101B/en
Priority to CN93101805A priority patent/CN1076489A/en
Publication of ITRM920100A1 publication Critical patent/ITRM920100A1/en
Application granted granted Critical
Publication of IT1254309B publication Critical patent/IT1254309B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Viene fornito un antigene associato a tumori sostanzialmente purificato proveniente dal fluido di coltura delle cellule di mammella umana, CG-5, del siero di paziente affetta da cancro alla mammella, e di fluido ascitico di paziente affetta da cancro alle ovaie. L'antigene nativo che ha un peso molecolare di circa 90.000 dalton è presente come un complesso di elevato peso molecolare. Sono fornite anche la purificazione e la caratterizzazione dell'antigene come pure le sequenze nucleotidiche che codificano per l'antigene 90K.A substantially purified tumor-associated antigen is provided from the human breast cell culture fluid, CG-5, from the serum of a patient suffering from breast cancer, and from ascitic fluid from a patient suffering from ovarian cancer. The native antigen which has a molecular weight of approximately 90,000 daltons is present as a high molecular weight complex. Purification and characterization of the antigen as well as nucleotide sequences encoding the 90K antigen are also provided.

ITRM920100A 1992-02-17 1992-02-17 GENETIC SEQUENCES FOR 90K ANTIGEN ASSOCIATED WITH CANCER. IT1254309B (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ITRM920100A IT1254309B (en) 1992-02-17 1992-02-17 GENETIC SEQUENCES FOR 90K ANTIGEN ASSOCIATED WITH CANCER.
PCT/EP1993/000382 WO1993016180A2 (en) 1992-02-17 1993-02-17 Sequences for a 90k tumor-associated antigen, immunoregulin-95 (ir-95)
AU34978/93A AU3497893A (en) 1992-02-17 1993-02-17 Sequences for a 90K tumor-associated antigen, immunoregulin-95 (IR-95)
ZA931101A ZA931101B (en) 1992-02-17 1993-02-17 Genetic sequences for a 90K Tumor-Associated Antigen, IR-95
CN93101805A CN1076489A (en) 1992-02-17 1993-02-17 The genetic sequence of 90K tumor associated antigen IR-95

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920100A IT1254309B (en) 1992-02-17 1992-02-17 GENETIC SEQUENCES FOR 90K ANTIGEN ASSOCIATED WITH CANCER.

Publications (3)

Publication Number Publication Date
ITRM920100A0 ITRM920100A0 (en) 1992-02-17
ITRM920100A1 ITRM920100A1 (en) 1993-08-17
IT1254309B true IT1254309B (en) 1995-09-14

Family

ID=11400692

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM920100A IT1254309B (en) 1992-02-17 1992-02-17 GENETIC SEQUENCES FOR 90K ANTIGEN ASSOCIATED WITH CANCER.

Country Status (5)

Country Link
CN (1) CN1076489A (en)
AU (1) AU3497893A (en)
IT (1) IT1254309B (en)
WO (1) WO1993016180A2 (en)
ZA (1) ZA931101B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995012681A1 (en) * 1993-11-05 1995-05-11 New York University Methods relating to ir-95
EP1248841B1 (en) 2000-01-10 2008-07-23 Novartis Vaccines and Diagnostics, Inc. Genes differentially expressed in breast cancer
US7081517B2 (en) 2000-01-10 2006-07-25 Chiron Corporation Genes differentially expressed in breast cancer
AU3483001A (en) * 2000-02-04 2001-08-14 Corixa Corp Compositions and methods for the therapy and diagnosis of ovarian cancer
ITRM20090081A1 (en) * 2009-02-25 2010-08-26 Stefano Iacobelli USE OF 90K PROTEIN INHIBITORS FOR THE PREPARATION OF A MEDICATION FOR THE CURE OR PREVENTION OF TUMORS.
CN101962405A (en) * 2010-09-30 2011-02-02 南开大学 Humanized breast cancer antigen and antibody thereof
CN110455848B (en) * 2018-05-08 2024-02-23 国家纳米科学中心 Iron ion longitudinal relaxation time sensor based on complexing reaction amplified signal, construction method and application thereof
WO2020099235A1 (en) 2018-11-12 2020-05-22 Mediapharma S.R.L. Bispecific antibodies directed against human 90k and either endosialin or her3

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL76877A (en) * 1984-11-02 1991-11-21 Oncogen Diagnostic method for the determination of human non-small cell lung carcinomas employing novel monoclonal antibodies and compositions containing said antibodies
IT1239719B (en) * 1990-04-23 1993-11-15 Univ Degli Studi Annunzio USE OF THE SP-2 MONOCLONAL ANTIBODY IN CLINICAL DIAGNOSTICS AND THE MONITORING OF THE PROGRESS OF HIV INFECTION

Also Published As

Publication number Publication date
ITRM920100A1 (en) 1993-08-17
ITRM920100A0 (en) 1992-02-17
CN1076489A (en) 1993-09-22
ZA931101B (en) 1994-08-17
AU3497893A (en) 1993-09-03
WO1993016180A2 (en) 1993-08-19
WO1993016180A3 (en) 1993-09-30

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