IT1239268B - Procedimento per la preparazione dell'acido 7-(d-2-amino-2-fenilacetamido)-3-cloro-3-cefem-4-carbossilico monoidrato e intermedio - Google Patents
Procedimento per la preparazione dell'acido 7-(d-2-amino-2-fenilacetamido)-3-cloro-3-cefem-4-carbossilico monoidrato e intermedioInfo
- Publication number
- IT1239268B IT1239268B IT22575A IT2257589A IT1239268B IT 1239268 B IT1239268 B IT 1239268B IT 22575 A IT22575 A IT 22575A IT 2257589 A IT2257589 A IT 2257589A IT 1239268 B IT1239268 B IT 1239268B
- Authority
- IT
- Italy
- Prior art keywords
- cefem
- phenylacetamide
- chlorine
- amino
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22575A IT1239268B (it) | 1989-12-01 | 1989-12-01 | Procedimento per la preparazione dell'acido 7-(d-2-amino-2-fenilacetamido)-3-cloro-3-cefem-4-carbossilico monoidrato e intermedio |
CA002028954A CA2028954A1 (en) | 1989-12-01 | 1990-11-01 | Process for preparing monohydrate 7-(d-2amino-2-phenylacetamido)-3-cefem-4-carboxylic acid and intermediate formed in the process |
EP90121179A EP0429895A1 (en) | 1989-12-01 | 1990-11-06 | Process for preparing monohydrate 7-(D-2-amino-2-phenylacetamido)-3-cefem-4-carboxylic acid and intermediate formed in the process |
JP2313790A JPH03181485A (ja) | 1989-12-01 | 1990-11-19 | 7―(d―2―アミノ―2―フェニルアセトアミド)―3―セフェム―4―カルボン酸一水和物の製造方法及びその方法で生成される中間体 |
KR1019900019443A KR910011866A (ko) | 1989-12-01 | 1990-11-29 | 모노하이드레이트 7-(d-2-아미노-2-페닐 아세트 아미도)-3-클로로-3-세펨-4-카복실산의 제조방법 및 공정중 형성된 중간체 |
AU67646/90A AU6764690A (en) | 1989-12-01 | 1990-11-30 | Process for preparing 7-(d-2-amino-2-phenylacetamido)-3-cefem-4-carboxylic acid monohydrate and intermediate formed in the process |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22575A IT1239268B (it) | 1989-12-01 | 1989-12-01 | Procedimento per la preparazione dell'acido 7-(d-2-amino-2-fenilacetamido)-3-cloro-3-cefem-4-carbossilico monoidrato e intermedio |
Publications (3)
Publication Number | Publication Date |
---|---|
IT8922575A0 IT8922575A0 (it) | 1989-12-01 |
IT8922575A1 IT8922575A1 (it) | 1991-06-01 |
IT1239268B true IT1239268B (it) | 1993-10-01 |
Family
ID=11198006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22575A IT1239268B (it) | 1989-12-01 | 1989-12-01 | Procedimento per la preparazione dell'acido 7-(d-2-amino-2-fenilacetamido)-3-cloro-3-cefem-4-carbossilico monoidrato e intermedio |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0429895A1 (it) |
JP (1) | JPH03181485A (it) |
KR (1) | KR910011866A (it) |
AU (1) | AU6764690A (it) |
CA (1) | CA2028954A1 (it) |
IT (1) | IT1239268B (it) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1251999B (it) * | 1991-11-11 | 1995-05-27 | Opos Biochimica Srl | Forma cristallina di un antibiotico cefalosporinico |
US5589593A (en) * | 1991-11-11 | 1996-12-31 | Biochimica Opos Spa | Crystalline form of a cephalosporin antibiotic |
CN101805357B (zh) * | 2010-04-28 | 2012-01-11 | 陶灵刚 | 一种头孢克洛化合物及其制法 |
CN104086573A (zh) * | 2014-07-24 | 2014-10-08 | 孙巧玲 | 头孢克洛的一锅法制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3925372A (en) * | 1973-02-23 | 1975-12-09 | Lilly Co Eli | Alpha-aminoacyl-3-halo cephalosporins |
DE3211034A1 (de) * | 1982-03-25 | 1983-09-29 | Bayer Ag, 5090 Leverkusen | 7-(alpha)-aminoacyl-3-chlorcephalosporine, verfahren zu ihrer herstellung sowie ihrer verwendung als arzneimittel |
-
1989
- 1989-12-01 IT IT22575A patent/IT1239268B/it active IP Right Grant
-
1990
- 1990-11-01 CA CA002028954A patent/CA2028954A1/en not_active Abandoned
- 1990-11-06 EP EP90121179A patent/EP0429895A1/en not_active Withdrawn
- 1990-11-19 JP JP2313790A patent/JPH03181485A/ja active Pending
- 1990-11-29 KR KR1019900019443A patent/KR910011866A/ko not_active Application Discontinuation
- 1990-11-30 AU AU67646/90A patent/AU6764690A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
IT8922575A0 (it) | 1989-12-01 |
KR910011866A (ko) | 1991-08-07 |
IT8922575A1 (it) | 1991-06-01 |
EP0429895A1 (en) | 1991-06-05 |
CA2028954A1 (en) | 1991-06-02 |
AU6764690A (en) | 1991-06-06 |
JPH03181485A (ja) | 1991-08-07 |
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TA | Fee payment date (situation as of event date), data collected since 19931001 |
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