IT1234193B - Nedocromil deriv.-anticholinergic compsn. - Google Patents
Nedocromil deriv.-anticholinergic compsn.Info
- Publication number
- IT1234193B IT1234193B IT8820684A IT2068488A IT1234193B IT 1234193 B IT1234193 B IT 1234193B IT 8820684 A IT8820684 A IT 8820684A IT 2068488 A IT2068488 A IT 2068488A IT 1234193 B IT1234193 B IT 1234193B
- Authority
- IT
- Italy
- Prior art keywords
- atropine
- nedocromil
- compsn
- parts
- anticholinergic
- Prior art date
Links
- RQTOOFIXOKYGAN-UHFFFAOYSA-N nedocromil Chemical compound CCN1C(C(O)=O)=CC(=O)C2=C1C(CCC)=C1OC(C(O)=O)=CC(=O)C1=C2 RQTOOFIXOKYGAN-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004398 nedocromil Drugs 0.000 title 1
- RKUNBYITZUJHSG-SPUOUPEWSA-N atropine Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)N2C)C(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-SPUOUPEWSA-N 0.000 abstract 4
- 229950007261 atropine methonitrate Drugs 0.000 abstract 2
- PDNHLCRMUIGNBV-UHFFFAOYSA-N 1-pyridin-2-ylethanamine Chemical compound CC(N)C1=CC=CC=N1 PDNHLCRMUIGNBV-UHFFFAOYSA-N 0.000 abstract 1
- 229930003347 Atropine Natural products 0.000 abstract 1
- RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 abstract 1
- JPKKQJKQTPNWTR-KQAYXBCTSA-N [(1r,5s)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2r)-3-hydroxy-2-phenylpropanoate;sulfuric acid;hydrate Chemical compound O.OS(O)(=O)=O.C1([C@H](CO)C(=O)OC2C[C@H]3CC[C@@H](C2)N3C)=CC=CC=C1.C1([C@H](CO)C(=O)OC2C[C@H]3CC[C@@H](C2)N3C)=CC=CC=C1 JPKKQJKQTPNWTR-KQAYXBCTSA-N 0.000 abstract 1
- 229960000396 atropine Drugs 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 229960001361 ipratropium bromide Drugs 0.000 abstract 1
- KEWHKYJURDBRMN-ZEODDXGYSA-M ipratropium bromide hydrate Chemical compound O.[Br-].O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 KEWHKYJURDBRMN-ZEODDXGYSA-M 0.000 abstract 1
- 229960002259 nedocromil sodium Drugs 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Pharmaceutical compsn. comprises 9-ethyl-6,9-dihydro-4,6-dioxo-10- propyl-4H- pyrano (3,2-g) quinoline-2,8-dicarboxylic acid (I) or its derivs. together with one or more anticholinergic agents (II). (I) include nedocronil sodium and (II) can be atropine, atropine methonitrate, atropine sulphate and ipratropium bromide. A nebuliser soln. is prepd. by dissolving 0.5 parts. wt. Nedocromil sodium (Ia) and atropine methonitrate (IIa) 0.2 parts in pumped water (BP) (to 100 parts vol.).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878712251A GB8712251D0 (en) | 1987-05-23 | 1987-05-23 | Formulation |
| GB8810716A GB2204790B (en) | 1987-05-23 | 1988-05-06 | Pharmaceutical compositions comprising a quinoline dicarboxylic acid and an anticholinergic agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8820684A0 IT8820684A0 (en) | 1988-05-20 |
| IT1234193B true IT1234193B (en) | 1992-05-06 |
Family
ID=26292281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8820684A IT1234193B (en) | 1987-05-23 | 1988-05-20 | Nedocromil deriv.-anticholinergic compsn. |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1234193B (en) |
-
1988
- 1988-05-20 IT IT8820684A patent/IT1234193B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| IT8820684A0 (en) | 1988-05-20 |
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