IT1206640B - Sintesi di azetidinoni funzionalizzati. - Google Patents
Sintesi di azetidinoni funzionalizzati.Info
- Publication number
- IT1206640B IT1206640B IT2800378A IT2800378A IT1206640B IT 1206640 B IT1206640 B IT 1206640B IT 2800378 A IT2800378 A IT 2800378A IT 2800378 A IT2800378 A IT 2800378A IT 1206640 B IT1206640 B IT 1206640B
- Authority
- IT
- Italy
- Prior art keywords
- derivs
- cooa
- intermediates
- lactamase inhibitors
- azetidin
- Prior art date
Links
- 239000003781 beta lactamase inhibitor Substances 0.000 title abstract 2
- 229940126813 beta-lactamase inhibitor Drugs 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title abstract 2
- 239000003782 beta lactam antibiotic agent Substances 0.000 title 1
- 239000002132 β-lactam antibiotic Substances 0.000 title 1
- 229940124586 β-lactam antibiotics Drugs 0.000 title 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003368 amide group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical compound O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 abstract 1
- -1 benzoylamino, benzyl-carbonylamino, phenoxyacetylamino Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 abstract 1
- 229960003324 clavulanic acid Drugs 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000000654 isopropylidene group Chemical group C(C)(C)=* 0.000 abstract 1
- 125000005544 phthalimido group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- CYTQBVOFDCPGCX-UHFFFAOYSA-N trimethyl phosphite Chemical compound COP(OC)OC CYTQBVOFDCPGCX-UHFFFAOYSA-N 0.000 abstract 1
- 150000003952 β-lactams Chemical class 0.000 abstract 1
Landscapes
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4806477 | 1977-11-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7828003A0 IT7828003A0 (it) | 1978-09-22 |
| IT1206640B true IT1206640B (it) | 1989-04-27 |
Family
ID=10447228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT2800378A IT1206640B (it) | 1977-11-18 | 1978-09-22 | Sintesi di azetidinoni funzionalizzati. |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1206640B (it) |
-
1978
- 1978-09-22 IT IT2800378A patent/IT1206640B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| IT7828003A0 (it) | 1978-09-22 |
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