IT1188556B - Amminoacido ed imminocido amminoalchilureido estere sostituito e composti estere - Google Patents

Amminoacido ed imminocido amminoalchilureido estere sostituito e composti estere

Info

Publication number
IT1188556B
IT1188556B IT19593/86A IT1959386A IT1188556B IT 1188556 B IT1188556 B IT 1188556B IT 19593/86 A IT19593/86 A IT 19593/86A IT 1959386 A IT1959386 A IT 1959386A IT 1188556 B IT1188556 B IT 1188556B
Authority
IT
Italy
Prior art keywords
foreign
amino
imminocid
alkylureid
replaced
Prior art date
Application number
IT19593/86A
Other languages
English (en)
Other versions
IT8619593A1 (it
IT8619593A0 (it
Inventor
Harold N Weller Iii
Eric M Gordon
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8619593A0 publication Critical patent/IT8619593A0/it
Publication of IT8619593A1 publication Critical patent/IT8619593A1/it
Application granted granted Critical
Publication of IT1188556B publication Critical patent/IT1188556B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT19593/86A 1985-02-28 1986-02-28 Amminoacido ed imminocido amminoalchilureido estere sostituito e composti estere IT1188556B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/707,123 US4638010A (en) 1985-02-28 1985-02-28 Ester substituted aminoalkanoylureido amino and imino acid and ester compounds

Publications (3)

Publication Number Publication Date
IT8619593A0 IT8619593A0 (it) 1986-02-28
IT8619593A1 IT8619593A1 (it) 1987-08-28
IT1188556B true IT1188556B (it) 1988-01-20

Family

ID=24840442

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19593/86A IT1188556B (it) 1985-02-28 1986-02-28 Amminoacido ed imminocido amminoalchilureido estere sostituito e composti estere

Country Status (7)

Country Link
US (1) US4638010A (it)
JP (1) JPS61227558A (it)
CA (1) CA1261332A (it)
DE (1) DE3606448A1 (it)
FR (1) FR2577925B1 (it)
GB (1) GB2171698B (it)
IT (1) IT1188556B (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190852A3 (en) * 1985-01-31 1988-11-02 Ajinomoto Co., Inc. Dipeptide derivatives and antihypertensive drugs containing them
US5013861A (en) * 1985-02-28 1991-05-07 E. R. Squibb & Sons, Inc. Ester substituted aminoalkanoylureido amino and imino acid and ester compounds
US5151513A (en) * 1988-04-29 1992-09-29 E. R. Squibb & Sons, Inc. N-heterocyclic alcohol derivatives
CA1340588C (en) * 1988-06-13 1999-06-08 Balraj Krishan Handa Amino acid derivatives
US6586466B2 (en) 1995-10-30 2003-07-01 Smithkline Beecham Corporation Carbohydrazide-protease inhibitors
EP0934291A1 (en) 1995-10-30 1999-08-11 Smithkline Beecham Corporation Protease inhibitors
JP3870298B2 (ja) * 1996-06-06 2007-01-17 株式会社大塚製薬工場 アミド誘導体
AU734302B2 (en) * 1997-05-08 2001-06-07 Smithkline Beecham Corporation Protease inhibitors
US20030144175A1 (en) * 1998-12-23 2003-07-31 Smithkline Beecham Corporation Protease inhibitors
US20030044399A1 (en) * 1998-12-23 2003-03-06 Smithkline Beecham Corporation Method of treatment
US6534498B1 (en) 1999-11-10 2003-03-18 Smithkline Beecham Corporation Protease inhibitors
US6583137B1 (en) 1999-11-10 2003-06-24 Smithkline Beecham Corporation Protease inhibitors
US6596715B1 (en) 1999-11-10 2003-07-22 Smithkline Beecham Corporation Protease inhibitors
CA2404206A1 (en) * 2000-03-21 2001-09-27 Smithkline Beecham Corporation Protease inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329473A (en) * 1979-06-01 1982-05-11 Almquist Ronald G Oxoalkanoic acid derivatives as inhibitors of angiotensin converting enzyme
US4402969A (en) * 1981-03-23 1983-09-06 Merck & Co., Inc. Antihypertensive proline derivatives
JPS58170752A (ja) * 1982-03-30 1983-10-07 Kureha Chem Ind Co Ltd Ｎ−カルバモイルアミノ酸誘導体
IT8222367V0 (it) * 1982-07-09 1982-07-09 Cavalli Alfredo Trafila per pasta sfoglia, particolarmente per macchine per la pasta di uso domestico.
US4623729A (en) * 1982-07-22 1986-11-18 E. R. Squibb & Sons, Inc. Acylalkylaminocarbonyl substituted amino and imino acid compounds

Also Published As

Publication number Publication date
US4638010A (en) 1987-01-20
GB2171698B (en) 1989-02-01
GB8603626D0 (en) 1986-03-19
IT8619593A1 (it) 1987-08-28
FR2577925B1 (fr) 1987-11-27
JPS61227558A (ja) 1986-10-09
IT8619593A0 (it) 1986-02-28
FR2577925A1 (fr) 1986-08-29
GB2171698A (en) 1986-09-03
CA1261332A (en) 1989-09-26
DE3606448A1 (de) 1986-08-28

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950227