IT1176322B - Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceutiche - Google Patents

Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceutiche

Info

Publication number
IT1176322B
IT1176322B IT21609/84A IT2160984A IT1176322B IT 1176322 B IT1176322 B IT 1176322B IT 21609/84 A IT21609/84 A IT 21609/84A IT 2160984 A IT2160984 A IT 2160984A IT 1176322 B IT1176322 B IT 1176322B
Authority
IT
Italy
Prior art keywords
ester
methoxy
methyl
mucosecretolytic
activity
Prior art date
Application number
IT21609/84A
Other languages
English (en)
Other versions
IT8421609A0 (it
Inventor
Mora Camillo Corvi
Original Assignee
Corvi Camillo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corvi Camillo Spa filed Critical Corvi Camillo Spa
Priority to IT21609/84A priority Critical patent/IT1176322B/it
Publication of IT8421609A0 publication Critical patent/IT8421609A0/it
Priority to DE8585105644T priority patent/DE3570979D1/de
Priority to EP85105644A priority patent/EP0166135B1/en
Priority to AT85105644T priority patent/ATE43964T1/de
Priority to US06/734,068 priority patent/US4665224A/en
Priority to JP60137080A priority patent/JPS6118746A/ja
Priority to KR1019850004511A priority patent/KR870000276A/ko
Application granted granted Critical
Publication of IT1176322B publication Critical patent/IT1176322B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/616—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety polycyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT21609/84A 1984-06-26 1984-06-26 Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceutiche IT1176322B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT21609/84A IT1176322B (it) 1984-06-26 1984-06-26 Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceutiche
DE8585105644T DE3570979D1 (en) 1984-06-26 1985-05-08 An ester of (+)6-methoxy- alpha -methyl-2-naphtalene acetic acid having mucosecretolytic, anti-inflammatory, analgesic, antipyretic activity, a process for its preparation and pharmaceutical compositions thereof
EP85105644A EP0166135B1 (en) 1984-06-26 1985-05-08 An ester of (+)6-methoxy- alpha -methyl-2-naphtalene acetic acid having mucosecretolytic, anti-inflammatory, analgesic, antipyretic activity, a process for its preparation and pharmaceutical compositions thereof
AT85105644T ATE43964T1 (de) 1984-06-26 1985-05-08 Ester der (+)-6-methoxy-alpha-methyl-2naphthalenessigs|ure mit mucosekretolytischer, entzuendungshemmender, schmerzstillender, fieber erniedrigender wirkung, dessen herstellungsverfahren und dessen pharmazeutische zusammensetzungen.
US06/734,068 US4665224A (en) 1984-06-26 1985-05-15 Ester of (+) 6-methoxy-α-methyl-2-naphthalene acetic acid having mucosecretolytic, anti-inflammatory, analgesic, antipyretic activity, a process for its preparation and pharmaceutical compositions thereof
JP60137080A JPS6118746A (ja) 1984-06-26 1985-06-25 （＋）６‐メトキシ‐α‐メチル‐２‐ナフタレン酢酸エステル，その製法，および医薬組成物
KR1019850004511A KR870000276A (ko) 1984-06-26 1985-06-25 (+)6-메톡시-α-메틸-2-나프탈렌 아세트산의 에스테르 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21609/84A IT1176322B (it) 1984-06-26 1984-06-26 Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceutiche

Publications (2)

Publication Number Publication Date
IT8421609A0 IT8421609A0 (it) 1984-06-26
IT1176322B true IT1176322B (it) 1987-08-18

Family

ID=11184278

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21609/84A IT1176322B (it) 1984-06-26 1984-06-26 Estere dell'acido (+) 6-metossi-alfa-metil-2-naftalenacetico avnete attivita' mucosecretolitica,antinfiammatoria,analgesica,antiprietica,procedimento per la sua preparazione e sue composizioni farmaceutiche

Country Status (7)

Country Link
US (1) US4665224A (it)
EP (1) EP0166135B1 (it)
JP (1) JPS6118746A (it)
KR (1) KR870000276A (it)
AT (1) ATE43964T1 (it)
DE (1) DE3570979D1 (it)
IT (1) IT1176322B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4912248A (en) * 1987-05-18 1990-03-27 The Procter & Gamble Company Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation
US6096920A (en) * 1997-01-08 2000-08-01 Albemarle Corporation Preparation of carboxylic compounds and their derivatives
US5792886A (en) * 1997-01-08 1998-08-11 Albemarle Corporation Production of racemic 2-(6-methoxy-2-naphthyl) propionic acid of precursors thereof
US6080888A (en) * 1997-01-08 2000-06-27 Albemarle Corporation Preparation of olefinic compounds and carboxylic derivatives thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
US4048330A (en) * 1967-01-13 1977-09-13 Syntex Corporation Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia
ZA701191B (en) * 1969-03-24 1971-09-29 Syntex Corp 2-(6-substituted-2'-naphthyl)acetic acid esters and process for producing same
IT1190663B (it) * 1982-01-21 1988-02-24 Ausonia Farma Srl Composto ad attivita' antiinfiammatoria,analgesica e mucoregolatrice,procedimento per la sua preparazione e relative composizioni farmaceutiche
DE3360037D1 (en) * 1982-04-15 1985-02-07 Firmenich & Cie 1(7)p-menthene-9-al and its use as a perfuming and flavouring agent

Also Published As

Publication number Publication date
KR870000276A (ko) 1987-02-17
US4665224A (en) 1987-05-12
EP0166135A3 (en) 1986-06-11
IT8421609A0 (it) 1984-06-26
EP0166135B1 (en) 1989-06-14
EP0166135A2 (en) 1986-01-02
DE3570979D1 (en) 1989-07-20
ATE43964T1 (de) 1989-06-15
JPS6118746A (ja) 1986-01-27

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