IT1162780B - Procedimento per la preparazione di 1 alfa,3 beta-di-idrossi delta-5-steroidi - Google Patents

Procedimento per la preparazione di 1 alfa,3 beta-di-idrossi delta-5-steroidi

Info

Publication number
IT1162780B
IT1162780B IT26409/79A IT2640979A IT1162780B IT 1162780 B IT1162780 B IT 1162780B IT 26409/79 A IT26409/79 A IT 26409/79A IT 2640979 A IT2640979 A IT 2640979A IT 1162780 B IT1162780 B IT 1162780B
Authority
IT
Italy
Prior art keywords
hydroxis
steroids
delta
beta
alpha
Prior art date
Application number
IT26409/79A
Other languages
English (en)
Other versions
IT7926409A0 (it
Inventor
Andor Furst
Ludwig Labler
Werner Meier
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IT7926409A0 publication Critical patent/IT7926409A0/it
Application granted granted Critical
Publication of IT1162780B publication Critical patent/IT1162780B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
IT26409/79A 1978-11-17 1979-10-11 Procedimento per la preparazione di 1 alfa,3 beta-di-idrossi delta-5-steroidi IT1162780B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU80545A LU80545A1 (de) 1978-11-17 1978-11-17 Verfahren zur herstellung von 1a,3s-dihydroxy->5-steroiden

Publications (2)

Publication Number Publication Date
IT7926409A0 IT7926409A0 (it) 1979-10-11
IT1162780B true IT1162780B (it) 1987-04-01

Family

ID=19729054

Family Applications (1)

Application Number Title Priority Date Filing Date
IT26409/79A IT1162780B (it) 1978-11-17 1979-10-11 Procedimento per la preparazione di 1 alfa,3 beta-di-idrossi delta-5-steroidi

Country Status (13)

Country Link
US (1) US4305881A (it)
JP (1) JPS5572200A (it)
AT (1) AT387392B (it)
BE (1) BE880031A (it)
CH (1) CH641815A5 (it)
DE (1) DE2945124A1 (it)
DK (1) DK486079A (it)
FR (2) FR2446841A1 (it)
GB (2) GB2036030B (it)
IL (1) IL58677A (it)
IT (1) IT1162780B (it)
LU (1) LU80545A1 (it)
NL (1) NL7908363A (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338250A (en) * 1981-04-27 1982-07-06 Wisconsin Alumni Research Foundation 1-Hydroxylation process
US4411833A (en) * 1982-05-26 1983-10-25 Wisconsin Alumni Research Foundation Method for preparing 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxycholesterol
JPS59500864A (ja) * 1982-05-26 1984-05-17 ウイスコンシン　アラムナイ　リサ−チ　フオンデ−シヨン ２６，２６．２６，２７．２７，２７―ヘキサフルオロ―１α，２５―ジヒドロキシコレステロール化合物及びその製造方法
US4500466A (en) * 1982-09-21 1985-02-19 The Firestone Tire & Rubber Company Method for preparing a zinc dimethacrylate powder having a specific surface area range
JPH0749435B2 (ja) * 1988-07-04 1995-05-31 帝人株式会社 １α，３β，２４−トリヒドロキシ−△▲上５▼−ステロイド類の製造方法
CN104145746A (zh) * 2013-05-13 2014-11-19 台湾矽能能源股份有限公司 温室的排热机构

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
US3887545A (en) * 1973-11-12 1975-06-03 Hoffmann La Roche Synthesis of 1{60 -hydroxylated cholesterol derivatives
DE2400189A1 (de) * 1974-01-03 1975-07-17 Basf Ag Verfahren zur herstellung von 1 alphahydroxy-cholesterinen
JPS539222B2 (it) * 1974-06-18 1978-04-04
JPS5324073B2 (it) * 1974-06-18 1978-07-18
US4022891A (en) * 1974-06-18 1977-05-10 Teijin Limited Novel 1α,24-dihydroxycholecalciferol compositions, novel precursors thereof, and processes for preparing them
IL45897A (en) * 1974-10-22 1978-12-17 Yeda Res & Dev Process for the preparation of 1 hydroxy-provitamin d3
IT1088094B (it) * 1976-10-14 1985-06-04 Hoffmann La Roche Derivati del pregnano

Also Published As

Publication number Publication date
NL7908363A (nl) 1980-05-20
AT387392B (de) 1989-01-10
FR2446841A1 (fr) 1980-08-14
FR2445838B1 (it) 1981-10-23
ATA732379A (de) 1988-06-15
CH641815A5 (de) 1984-03-15
FR2445838A1 (fr) 1980-08-01
DE2945124C2 (it) 1989-04-06
IL58677A (en) 1983-03-31
IT7926409A0 (it) 1979-10-11
GB2036030A (en) 1980-06-25
GB2036030B (en) 1983-05-05
GB2104524B (en) 1983-07-13
JPS6337800B2 (it) 1988-07-27
DE2945124A1 (de) 1980-06-04
DK486079A (da) 1980-05-18
LU80545A1 (de) 1980-06-05
FR2446841B1 (it) 1983-10-21
BE880031A (fr) 1980-05-14
JPS5572200A (en) 1980-05-30
GB2104524A (en) 1983-03-09
US4305881A (en) 1981-12-15
IL58677A0 (en) 1980-02-29

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