IT1156989B - Procedimento per la preparazione della i.4 bis piperonil piperazina e dei composti analoghi - Google Patents

Procedimento per la preparazione della i.4 bis piperonil piperazina e dei composti analoghi

Info

Publication number
IT1156989B
IT1156989B IT67951/78A IT6795178A IT1156989B IT 1156989 B IT1156989 B IT 1156989B IT 67951/78 A IT67951/78 A IT 67951/78A IT 6795178 A IT6795178 A IT 6795178A IT 1156989 B IT1156989 B IT 1156989B
Authority
IT
Italy
Prior art keywords
piperonil
piperazina
bis
procedure
preparation
Prior art date
Application number
IT67951/78A
Other languages
English (en)
Other versions
IT7867951A0 (it
Inventor
Armando Raimondi
Placido Poidomani
Giancarlo Scapini
Gian Piero Gardini
Original Assignee
Geymonat Sud Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geymonat Sud Spa filed Critical Geymonat Sud Spa
Publication of IT7867951A0 publication Critical patent/IT7867951A0/it
Priority to IT67951/78A priority Critical patent/IT1156989B/it
Priority to GR58768A priority patent/GR68530B/el
Priority to GB7912963A priority patent/GB2020274B/en
Priority to ES479627A priority patent/ES479627A1/es
Priority to NL7903062A priority patent/NL7903062A/xx
Priority to JP4961179A priority patent/JPS54154777A/ja
Priority to PT69540A priority patent/PT69540A/pt
Priority to FR7910524A priority patent/FR2424263A1/fr
Priority to BE0/194864A priority patent/BE875886A/xx
Priority to DE2916991A priority patent/DE2916991C3/de
Priority to CH391279A priority patent/CH638192A5/it
Priority to US06/034,040 priority patent/US4264770A/en
Application granted granted Critical
Publication of IT1156989B publication Critical patent/IT1156989B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
IT67951/78A 1978-04-27 1978-04-27 Procedimento per la preparazione della i.4 bis piperonil piperazina e dei composti analoghi IT1156989B (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT67951/78A IT1156989B (it) 1978-04-27 1978-04-27 Procedimento per la preparazione della i.4 bis piperonil piperazina e dei composti analoghi
GR58768A GR68530B (it) 1978-04-27 1979-04-03
GB7912963A GB2020274B (en) 1978-04-27 1979-04-12 Process for preparing 1,4-bis-benzyl piperazines and substitution dervatives thereof
ES479627A ES479627A1 (es) 1978-04-27 1979-04-17 Un procedimiento para la preparacion de 1,4-bis-piperonilpi-peracina y similares.
NL7903062A NL7903062A (nl) 1978-04-27 1979-04-19 Werkwijze ter bereiding van 1,4-bis-piperonylpiperazine en analoge verbindingen.
JP4961179A JPS54154777A (en) 1978-04-27 1979-04-21 Manufacture of 1*44bisspiperonylpiperazine and analogue compound
PT69540A PT69540A (en) 1978-04-27 1979-04-24 Process for preparing 1,4-bis-piperonylpiperazine and similar compounds
FR7910524A FR2424263A1 (fr) 1978-04-27 1979-04-25 Procede pour la preparation de la 1,4-bis-piperonylpiperazine et de composes analogues
BE0/194864A BE875886A (fr) 1978-04-27 1979-04-26 Procede pour la preparation de la 1,4-bis-piperonylpiperzine et de composes analogues
DE2916991A DE2916991C3 (de) 1978-04-27 1979-04-26 Verfahren zur Herstellung von 1,4-Bis-(arylmethyl)-pipera~inverbindungen
CH391279A CH638192A5 (it) 1978-04-27 1979-04-26 Procedimento per la preparazione della 1,4-bis-piperonilpiperazina e dei composti analoghi.
US06/034,040 US4264770A (en) 1978-04-27 1979-04-27 Process for preparing 1,4-bis-piperonylpiperazine and similar compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT67951/78A IT1156989B (it) 1978-04-27 1978-04-27 Procedimento per la preparazione della i.4 bis piperonil piperazina e dei composti analoghi

Publications (2)

Publication Number Publication Date
IT7867951A0 IT7867951A0 (it) 1978-04-27
IT1156989B true IT1156989B (it) 1987-02-04

Family

ID=11306645

Family Applications (1)

Application Number Title Priority Date Filing Date
IT67951/78A IT1156989B (it) 1978-04-27 1978-04-27 Procedimento per la preparazione della i.4 bis piperonil piperazina e dei composti analoghi

Country Status (12)

Country Link
US (1) US4264770A (it)
JP (1) JPS54154777A (it)
BE (1) BE875886A (it)
CH (1) CH638192A5 (it)
DE (1) DE2916991C3 (it)
ES (1) ES479627A1 (it)
FR (1) FR2424263A1 (it)
GB (1) GB2020274B (it)
GR (1) GR68530B (it)
IT (1) IT1156989B (it)
NL (1) NL7903062A (it)
PT (1) PT69540A (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3066655D1 (en) * 1979-12-20 1984-03-22 Hoechst Ag Process for the production of n,n'-diaryl-alkylene diamines or n,n',n"-triaryl-dialkylene triamines
US4609436A (en) * 1984-01-06 1986-09-02 The Dow Chemical Company Process for decolorizing polyethylene polyamines with a chlorinated hydrocarbon
WO1998037077A1 (en) * 1997-02-24 1998-08-27 Zymogenetics, Inc. Calcitonin mimetics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2870152A (en) * 1959-01-20 Unilcu
US2415786A (en) * 1944-01-06 1947-02-11 Burroughs Wellcome Co Unsymmetrically substituted piperazines
US2695294A (en) * 1952-12-19 1954-11-23 Mcneilab Inc N, n'-substituted diamine compounds and method of making the same
US2887488A (en) * 1957-09-23 1959-05-19 Du Pont Piperazine derivatives
FR1312427A (fr) * 1961-04-12 1962-12-21 Science Union Et Compagnie Soc Nouveaux dérivés de la pipérazine et leurs préparations
JPS606946B2 (ja) * 1974-03-12 1985-02-21 東京田辺製薬株式会社 Ｎ−（３，３−ジフエニルプロピル）−ｎ’−アラルキル置換ピペラジンおよびその塩の製法

Also Published As

Publication number Publication date
GR68530B (it) 1982-01-14
JPS54154777A (en) 1979-12-06
GB2020274A (en) 1979-11-14
DE2916991A1 (de) 1979-10-31
BE875886A (fr) 1979-08-16
NL7903062A (nl) 1979-10-30
ES479627A1 (es) 1979-08-01
FR2424263B1 (it) 1983-02-11
IT7867951A0 (it) 1978-04-27
DE2916991C3 (de) 1981-02-05
PT69540A (en) 1979-05-01
DE2916991B2 (de) 1980-05-29
GB2020274B (en) 1982-08-25
FR2424263A1 (fr) 1979-11-23
US4264770A (en) 1981-04-28
CH638192A5 (it) 1983-09-15

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