IT1142142B - 5alfa-androstan-17beta-carbossilati e 5beta-androstan-17beta-carbossilati - Google Patents
5alfa-androstan-17beta-carbossilati e 5beta-androstan-17beta-carbossilatiInfo
- Publication number
- IT1142142B IT1142142B IT25692/81A IT2569281A IT1142142B IT 1142142 B IT1142142 B IT 1142142B IT 25692/81 A IT25692/81 A IT 25692/81A IT 2569281 A IT2569281 A IT 2569281A IT 1142142 B IT1142142 B IT 1142142B
- Authority
- IT
- Italy
- Prior art keywords
- 17beta
- androstan
- carboxylate
- 5alfa
- 5beta
- Prior art date
Links
- PBXJGQQGODZSQR-WQBJWTDHSA-N (5s,8r,9s,10s,13s,14s,17s)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthrene-17-carboxylic acid Chemical compound C1CCC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)C(O)=O)[C@@H]4[C@@H]3CC[C@@H]21 PBXJGQQGODZSQR-WQBJWTDHSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21929380A | 1980-12-22 | 1980-12-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8125692A0 IT8125692A0 (it) | 1981-12-18 |
| IT1142142B true IT1142142B (it) | 1986-10-08 |
Family
ID=22818692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT25692/81A IT1142142B (it) | 1980-12-22 | 1981-12-18 | 5alfa-androstan-17beta-carbossilati e 5beta-androstan-17beta-carbossilati |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS57131000A (it) |
| BE (1) | BE891585A (it) |
| DE (1) | DE3149475A1 (it) |
| FR (1) | FR2496668A1 (it) |
| GB (1) | GB2089808A (it) |
| IT (1) | IT1142142B (it) |
| NL (1) | NL8105455A (it) |
| ZA (1) | ZA817929B (it) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL78144A0 (en) * | 1985-04-04 | 1986-07-31 | Draco Ab | Novel androstane-17beta-carboxylic acid esters |
| SE8501693D0 (sv) * | 1985-04-04 | 1985-04-04 | Draco Ab | Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters |
| ES2041245T3 (es) * | 1985-10-23 | 1993-11-16 | The Upjohn Company | Esteroides angioestaticos. |
| JP5780521B2 (ja) | 2008-05-28 | 2015-09-16 | リベラジェン・バイオファーマ・インコーポレイテッドＲｅｖｅｒａＧｅｎ ＢｉｏＰｈａｒｍａ，Ｉｎｃ． | 疾患を治療するための、ＮＦ−κＢの非ホルモン性ステロイド調節因子 |
| WO2011127048A2 (en) | 2010-04-05 | 2011-10-13 | Validus Biopharma | NON-HORMONAL STEROID MODULATORS OF NF-ĸB FOR TREATMENT OF DISEASE |
| US10799514B2 (en) | 2015-06-29 | 2020-10-13 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-kappa beta for treatment of disease |
| US11382922B2 (en) | 2019-03-07 | 2022-07-12 | Reveragen Biopharma, Inc. | Aqueous oral pharmaceutical suspension compositions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3828080A (en) * | 1972-01-20 | 1974-08-06 | Glaxo Lab Ltd | Androstane-17beta-carboxylic acids and processes for the preparation thereof |
| DE3105307A1 (de) * | 1980-02-15 | 1981-12-10 | Glaxo Group Ltd., London | "androstan-carbothioate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen" |
-
1981
- 1981-11-16 ZA ZA817929A patent/ZA817929B/xx unknown
- 1981-12-03 NL NL8105455A patent/NL8105455A/nl not_active Application Discontinuation
- 1981-12-14 DE DE19813149475 patent/DE3149475A1/de not_active Withdrawn
- 1981-12-18 IT IT25692/81A patent/IT1142142B/it active
- 1981-12-21 FR FR8123840A patent/FR2496668A1/fr active Pending
- 1981-12-22 JP JP56207928A patent/JPS57131000A/ja active Pending
- 1981-12-22 GB GB8138530A patent/GB2089808A/en not_active Withdrawn
- 1981-12-22 BE BE0/206909A patent/BE891585A/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IT8125692A0 (it) | 1981-12-18 |
| BE891585A (fr) | 1982-06-22 |
| DE3149475A1 (de) | 1982-07-15 |
| ZA817929B (en) | 1982-10-27 |
| GB2089808A (en) | 1982-06-30 |
| NL8105455A (nl) | 1982-07-16 |
| JPS57131000A (en) | 1982-08-13 |
| FR2496668A1 (fr) | 1982-06-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BE887534A (fr) | Sandwichpaneelelement | |
| BE889577A (nl) | Golfvormsynthese | |
| BE891422A (fr) | Degrilleur | |
| FI810237L (fi) | Profylaktisk komposition foer munnens vaord | |
| FI824264A0 (fi) | Infaestningsanordning foer cylinderlaos | |
| IT1167391B (it) | Carbossi e carbossi sostituiti alcanoil e cicloalcanoil peptidi | |
| BR8108921A (pt) | Fecho | |
| IT1193576B (it) | 17alfa-acilossi-5beta-corticoidi e 17alfa-acilossi-5alfa-corticoidi | |
| FI812129L (fi) | Imidazolidinonderivat | |
| BE889192A (fr) | Recolteuse-hacheuse | |
| IT1142142B (it) | 5alfa-androstan-17beta-carbossilati e 5beta-androstan-17beta-carbossilati | |
| BE889004A (nl) | Grijper | |
| BE889708A (fr) | Sous-soleuse | |
| BG33404A1 (bg) | Registrovo aritmetichno ustrojjstvo | |
| BE891654A (fr) | Schuifdeur | |
| BE888818A (fr) | Telerupteur | |
| BG32324A1 (bg) | Telopodavahho ustrojjstvo | |
| BE887835A (fr) | Fluidumsysteem | |
| FI811180L (fi) | Stroemfoersoerjningsdon | |
| FI810834L (fi) | Herbicida 2-haloacetanilider | |
| FI810444L (fi) | Androstankarbotioater | |
| BR6000116U (pt) | Fecho | |
| BR6000117U (pt) | Fecho | |
| BR6000452U (pt) | Manual e bloco | |
| AR219450A1 (es) | Portasachet |