IT1124740B - PYRIMIDONIC COMPOUNDS USEFUL AS HISTAMINE H2 ANTAGONISTS AND PROCEDURE TO PREPARE THEM - Google Patents

PYRIMIDONIC COMPOUNDS USEFUL AS HISTAMINE H2 ANTAGONISTS AND PROCEDURE TO PREPARE THEM

Info

Publication number
IT1124740B
IT1124740B IT30235/76A IT3023576A IT1124740B IT 1124740 B IT1124740 B IT 1124740B IT 30235/76 A IT30235/76 A IT 30235/76A IT 3023576 A IT3023576 A IT 3023576A IT 1124740 B IT1124740 B IT 1124740B
Authority
IT
Italy
Prior art keywords
pyrimidonic
histamine
antagonists
prepare
procedure
Prior art date
Application number
IT30235/76A
Other languages
Italian (it)
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Application granted granted Critical
Publication of IT1124740B publication Critical patent/IT1124740B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IT30235/76A 1975-12-29 1976-12-09 PYRIMIDONIC COMPOUNDS USEFUL AS HISTAMINE H2 ANTAGONISTS AND PROCEDURE TO PREPARE THEM IT1124740B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5300175 1975-12-29

Publications (1)

Publication Number Publication Date
IT1124740B true IT1124740B (en) 1986-05-14

Family

ID=10466233

Family Applications (2)

Application Number Title Priority Date Filing Date
IT30235/76A IT1124740B (en) 1975-12-29 1976-12-09 PYRIMIDONIC COMPOUNDS USEFUL AS HISTAMINE H2 ANTAGONISTS AND PROCEDURE TO PREPARE THEM
IT7919107A IT7919107A0 (en) 1975-12-29 1979-01-05 PHARMACOLOGICALLY ACTIVE COMPOUNDS.

Family Applications After (1)

Application Number Title Priority Date Filing Date
IT7919107A IT7919107A0 (en) 1975-12-29 1979-01-05 PHARMACOLOGICALLY ACTIVE COMPOUNDS.

Country Status (37)

Country Link
JP (1) JPS5283388A (en)
AR (1) AR222290A1 (en)
AT (1) AT360024B (en)
AU (1) AU508123B2 (en)
BE (1) BE849810A (en)
BG (1) BG29722A3 (en)
CA (1) CA1073458A (en)
CH (1) CH631981A5 (en)
CS (1) CS203995B2 (en)
DD (1) DD128588A5 (en)
DE (1) DE2658267A1 (en)
DK (1) DK587076A (en)
EG (1) EG12439A (en)
ES (1) ES454656A1 (en)
FI (1) FI62668C (en)
FR (1) FR2336935A1 (en)
GR (1) GR62441B (en)
HU (1) HU175171B (en)
IE (1) IE45082B1 (en)
IL (1) IL51040A (en)
IT (2) IT1124740B (en)
LU (1) LU76481A1 (en)
MW (1) MW5076A1 (en)
MX (1) MX5119E (en)
NL (1) NL7614538A (en)
NO (1) NO146396C (en)
NZ (1) NZ182759A (en)
OA (1) OA05526A (en)
PH (1) PH14723A (en)
PL (1) PL104376B1 (en)
PT (1) PT65949B (en)
RO (1) RO72475A (en)
SE (1) SE431544B (en)
SU (1) SU791235A3 (en)
YU (1) YU311676A (en)
ZA (1) ZA767198B (en)
ZM (1) ZM14376A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ186511A (en) 1977-03-19 1980-11-14 Smith Kline French Lab 3-substituted alkylamino-6-substituted alkyl-1,2,4-triazin-5-ones and pharmaceutical compositions 3-substituted thio-1,2,4-triazin-5-ones
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
IN151188B (en) * 1978-02-13 1983-03-05 Smith Kline French Lab
US4539207A (en) * 1978-02-13 1985-09-03 Smith Kline & French Laboratories Limited Pyrimidine compounds
PH16240A (en) * 1978-04-11 1983-08-11 Smith Kline French Lab Process for making histamine antagonist
ZA792607B (en) * 1978-05-30 1980-07-30 Smith Kline French Lab Nitro compounds
ZA793392B (en) * 1978-07-15 1980-08-27 Smith Kline French Lab Isoureas and isothioureas
US4309435A (en) 1978-10-16 1982-01-05 Imperial Chemical Industries Ltd. Antisecretory guanidine derivatives and pharmaceutical compositions containing them
US4374836A (en) 1978-10-16 1983-02-22 Imperial Chemical Industries Ltd. Antisecretory heterocyclic derivatives, process for their manufacture and pharmaceutical compositions containing them
US4496567A (en) * 1978-11-13 1985-01-29 Smith Kline & French Laboratories Limited Phenyl alkylaminopyrimidones
US4521418A (en) * 1979-02-21 1985-06-04 Smith Kline & French Laboratories Limited Guanidinothiazolyl derivatives
US4255428A (en) 1979-03-24 1981-03-10 Smith Kline & French Laboratories Limited 5-(Hydroxypyridylalkyl)-4-pyrimidones
JPS55133379A (en) * 1979-04-05 1980-10-17 Smith Kline French Lab Pyrimidone compound
EP0017680B1 (en) * 1979-04-11 1982-04-21 Smith Kline & French Laboratories Limited Pyrimidone derivatives, process for preparing them and pharmaceutical compositions containing them
JPS55145683A (en) * 1979-04-26 1980-11-13 Smith Kline French Lab Pyrimidone derivative
CA1155842A (en) * 1980-03-29 1983-10-25 Thomas H. Brown Compounds
ZW21281A1 (en) * 1980-10-01 1981-11-18 Smith Kline French Lab Amine derivatives
IE53068B1 (en) * 1981-06-15 1988-05-25 Merck & Co Inc Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors
PT75074B (en) * 1981-06-27 1986-02-26 Smith Kline French Lab Process for preparing certain pyrimidone derivatives and compositions containing them
US6417366B2 (en) * 1999-06-24 2002-07-09 Abbott Laboratories Preparation of quinoline-substituted carbonate and carbamate derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
IN146736B (en) * 1975-10-02 1979-08-25 Smith Kline French Lab

Also Published As

Publication number Publication date
AT360024B (en) 1980-12-10
FI62668C (en) 1983-02-10
FR2336935B1 (en) 1980-03-21
ZA767198B (en) 1977-11-30
PT65949B (en) 1978-06-15
GR62441B (en) 1979-04-12
YU311676A (en) 1983-01-21
PT65949A (en) 1977-01-01
IL51040A (en) 1980-12-31
DE2658267A1 (en) 1977-07-07
ES454656A1 (en) 1977-11-16
IE45082B1 (en) 1982-06-16
ATA960876A (en) 1980-05-15
SU791235A3 (en) 1980-12-23
EG12439A (en) 1979-09-30
AU2097676A (en) 1978-07-06
JPS5283388A (en) 1977-07-12
JPS6129355B2 (en) 1986-07-05
CA1073458A (en) 1980-03-11
CH631981A5 (en) 1982-09-15
NO764370L (en) 1977-06-30
DK587076A (en) 1977-06-30
DD128588A5 (en) 1977-11-30
HU175171B (en) 1980-05-28
PL104376B1 (en) 1979-08-31
SE7614620L (en) 1977-06-30
NL7614538A (en) 1977-07-01
FI62668B (en) 1982-10-29
IL51040A0 (en) 1977-02-28
MW5076A1 (en) 1978-02-08
FR2336935A1 (en) 1977-07-29
MX5119E (en) 1983-03-24
NZ182759A (en) 1978-06-02
CS203995B2 (en) 1981-03-31
LU76481A1 (en) 1977-06-15
NO146396C (en) 1982-09-22
PH14723A (en) 1981-11-13
SE431544B (en) 1984-02-13
RO72475A (en) 1982-10-26
NO146396B (en) 1982-06-14
OA05526A (en) 1981-04-30
AR222290A1 (en) 1981-05-15
ZM14376A1 (en) 1977-08-22
BG29722A3 (en) 1981-01-15
BE849810A (en) 1977-06-23
IE45082L (en) 1977-06-29
AU508123B2 (en) 1980-03-13
IT7919107A0 (en) 1979-01-05
FI763664A7 (en) 1977-06-30

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