IT1113753B - Asymmetric hydrogenation of olefins, carbonyl cpds. or nitriles - using transition metal complex of asymmetric amino-phosphine - Google Patents
Asymmetric hydrogenation of olefins, carbonyl cpds. or nitriles - using transition metal complex of asymmetric amino-phosphineInfo
- Publication number
- IT1113753B IT1113753B IT2013977A IT2013977A IT1113753B IT 1113753 B IT1113753 B IT 1113753B IT 2013977 A IT2013977 A IT 2013977A IT 2013977 A IT2013977 A IT 2013977A IT 1113753 B IT1113753 B IT 1113753B
- Authority
- IT
- Italy
- Prior art keywords
- asymmetric
- nitriles
- phosphine
- olefins
- transition metal
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
New asymmetric aminophosphines are of formula (I) P(R1)x(NR2R3)3-x (I) (where R1 is alkyl, aryl, alkylaryl, cycloalkyl, alkoxy, aryloxy, alkylthio, arylthio, alkylphosphino, arylphosphino, or aminophosphino; x = 0-2; R2 and R3 are alkyl, aryl, alklaryl, aralkyl or cycloalkyl, at least one of which contains one or more asymmetric centres). In an examples R(-)-N-acetyl-phenylalamine is prepd. by hydrogenating alpha-acetamido-cinnamic acid in the presence of a catalyst prepd. from u-dichloro-tetrakis (ethylene)-dirhodium and N,N'-bis S(-)-d-methylbenzyl -N,N'-(diphenylphosphine)-ethylenediamine. The process is esp. useful for preparing optically active amino acids from the corresp. olefinically unsatd. amino acids. Prodts. of high optical purity (e.g. 73-84%) can be obtd. in certain cases.
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2013977A IT1113753B (en) | 1977-02-10 | 1977-02-10 | Asymmetric hydrogenation of olefins, carbonyl cpds. or nitriles - using transition metal complex of asymmetric amino-phosphine |
CA275,775A CA1109074A (en) | 1976-04-26 | 1977-04-06 | Asymmetrical hydrogenation and related means for this purpose |
AU24407/77A AU523259B2 (en) | 1976-04-26 | 1977-04-19 | Asymmetrical hydrogenation |
GB16691/77A GB1580461A (en) | 1976-04-26 | 1977-04-21 | Transition metal complexes |
DD7700198557A DD132487A5 (en) | 1976-04-26 | 1977-04-22 | METHOD FOR ASYMMETRIC HYDROGENATION |
CH503677A CH629166A5 (en) | 1976-04-26 | 1977-04-22 | Process for asymmetrical hydrogenation and means suitable for this purpose |
DD77206208A DD137233A5 (en) | 1976-04-26 | 1977-04-22 | METHOD FOR THE PRODUCTION OF COMPLEXES WITH ASYMMETRIC AMINO PHOSPHINS |
LU77197A LU77197A1 (en) | 1976-04-26 | 1977-04-25 | |
SE7704738A SE434918B (en) | 1976-04-26 | 1977-04-25 | CATALYST SYSTEM AND ITS USE FOR ASYMMETRIC HYDRATION |
NO771419A NO771419L (en) | 1976-04-26 | 1977-04-25 | NEW AMINOPHOSPHINES AND PROCEDURES FOR THEIR PREPARATION |
HU82466A HUT34037A (en) | 1976-04-26 | 1977-04-25 | Process for production of optically active new amino-phosphyn compounds |
YU01075/77A YU107577A (en) | 1976-04-26 | 1977-04-25 | Process for obtaining a catalytical complex active in asymmetric hydrogenation |
DK180877A DK180877A (en) | 1976-04-26 | 1977-04-25 | ASYMMETRIC HYDROGERATION AND AGENTS FOR THIS PURPOSE |
FR7712435A FR2349555A1 (en) | 1976-04-26 | 1977-04-25 | ASYMETRIC HYDROGENATION AND MEANS TO ACHIEVE IT |
HU82465A HUT33991A (en) | 1976-04-26 | 1977-04-25 | Process for assimetric hydrogenation by utilizing amino-phosphyn-interim-metallic complex catalizators |
NLAANVRAGE7704570,A NL180096C (en) | 1976-04-26 | 1977-04-26 | METHOD FOR THE ASYMMETRIC HYDROGENATION OF PROCHIRAL OR RACEMIC OLEGINS OR CO- AND / OR CN GROUPS CONTAINING COMPOSITIONS, METHOD FOR THE PREPARATION OF ASYMMETRIC AMINOPHOSPHERS AND METHOD FOR THE PRODUCTION OF A COMPLEX HYDROGEN METAL FOR PRODUCTION OF A COMPLEX HYDROGENIC PRODUCTION A TRANSITION METAL. |
DE2759683A DE2759683C3 (en) | 1976-04-26 | 1977-04-26 | Asymmetric aminophosphines, processes for their preparation and their use |
DE2759684A DE2759684C2 (en) | 1976-04-26 | 1977-04-26 | Process for the asymmetric hydrogenation of substrates |
DE2718533A DE2718533C3 (en) | 1976-04-26 | 1977-04-26 | Catalyst system and its use for asymmetric hydrogenation |
JP4750177A JPS52151127A (en) | 1976-04-26 | 1977-04-26 | Asymmetric aminophosphine*preparation thereof and method of asymmetric hydrogen addition |
NO773738A NO773738L (en) | 1976-04-26 | 1977-10-31 | PROCEDURES FOR ASYMMETRIC HYDROGENATION |
CA000374038A CA1119183A (en) | 1976-04-26 | 1981-03-27 | Asymmetrical aminophosphines, belonging to a novel class of amine derivatives of the phosphorus |
SE8304837A SE460066B (en) | 1976-04-26 | 1983-09-09 | ASYMMETRIC AMINOPHOSPHINES AND APPLICATION OF THESE FOODS PREPARATION OF CATALYSTS FOR HYDROGENATION OF OLEFINES TO OPTICALLY ACTIVE COMPOUNDS |
AU30546/84A AU572169B2 (en) | 1976-04-26 | 1984-07-12 | Rnodium and 2(s),5(s)- dimethyl-n,n'bis (diphenylphosphino) (+)-piperazine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2013977A IT1113753B (en) | 1977-02-10 | 1977-02-10 | Asymmetric hydrogenation of olefins, carbonyl cpds. or nitriles - using transition metal complex of asymmetric amino-phosphine |
Publications (1)
Publication Number | Publication Date |
---|---|
IT1113753B true IT1113753B (en) | 1986-01-20 |
Family
ID=11164124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT2013977A IT1113753B (en) | 1976-04-26 | 1977-02-10 | Asymmetric hydrogenation of olefins, carbonyl cpds. or nitriles - using transition metal complex of asymmetric amino-phosphine |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1113753B (en) |
-
1977
- 1977-02-10 IT IT2013977A patent/IT1113753B/en active
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