IT1113038B - Mercapto:propionamido-acetic acid derivs. - having mucolytic muco-regulating, anti-seborrhoeic and anti-dandruff activities - Google Patents
Mercapto:propionamido-acetic acid derivs. - having mucolytic muco-regulating, anti-seborrhoeic and anti-dandruff activitiesInfo
- Publication number
- IT1113038B IT1113038B IT2077079A IT2077079A IT1113038B IT 1113038 B IT1113038 B IT 1113038B IT 2077079 A IT2077079 A IT 2077079A IT 2077079 A IT2077079 A IT 2077079A IT 1113038 B IT1113038 B IT 1113038B
- Authority
- IT
- Italy
- Prior art keywords
- mucolytic
- acetic acid
- seborrhoeic
- muco
- propionamido
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 4
- 230000000510 mucolytic effect Effects 0.000 title abstract 2
- 208000001840 Dandruff Diseases 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 title 1
- 125000003396 thiol group Chemical class [H]S* 0.000 title 1
- 206010000496 acne Diseases 0.000 abstract 2
- FSCGLKWYHHSLST-UHFFFAOYSA-N 2-(3-sulfanylpropanoylamino)acetic acid Chemical compound OC(=O)CNC(=O)CCS FSCGLKWYHHSLST-UHFFFAOYSA-N 0.000 abstract 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 101100277337 Arabidopsis thaliana DDM1 gene Proteins 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 101150113676 chr1 gene Proteins 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Landscapes
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Mercaptopropionamido-acetic acid derivs. of formula (I) are new: R2OOC-CH2-S-(CHR1)n-CONH-CH2COOR (R is H or 2-20C alkyl; n is 1 or 2; when n is 1, R1 is Me; when n is 21 R1 is H; R2 is H or 1/2Ca). Cpds. (I) have mucolytic and mucoregulating activity and can be used e.g. to treat bronchial hypersecretions. They can be formulated as tablets, aerosols, suppositories, etc. The cpds. also act on skin, showing high antiseborrhoeic activity which favours the cleansing and hygiene of fatty skin affected with boils, comedones and acne; and they also have antidandruff activity.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2077079A IT1113038B (en) | 1979-03-06 | 1979-03-06 | Mercapto:propionamido-acetic acid derivs. - having mucolytic muco-regulating, anti-seborrhoeic and anti-dandruff activities |
EP19800101108 EP0015544B1 (en) | 1979-03-06 | 1980-03-05 | Derivatives of the mercaptopropionamido-acetic acid, process for the preparation thereof and compositions |
DE8080101108T DE3061527D1 (en) | 1979-03-06 | 1980-03-05 | Derivatives of the mercaptopropionamido-acetic acid, process for the preparation thereof and compositions |
AT80101108T ATE2172T1 (en) | 1979-03-06 | 1980-03-05 | MERCAPTOPROPIONAMIDO-ACETIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2077079A IT1113038B (en) | 1979-03-06 | 1979-03-06 | Mercapto:propionamido-acetic acid derivs. - having mucolytic muco-regulating, anti-seborrhoeic and anti-dandruff activities |
Publications (2)
Publication Number | Publication Date |
---|---|
IT7920770A0 IT7920770A0 (en) | 1979-03-06 |
IT1113038B true IT1113038B (en) | 1986-01-20 |
Family
ID=11171807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT2077079A IT1113038B (en) | 1979-03-06 | 1979-03-06 | Mercapto:propionamido-acetic acid derivs. - having mucolytic muco-regulating, anti-seborrhoeic and anti-dandruff activities |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1113038B (en) |
-
1979
- 1979-03-06 IT IT2077079A patent/IT1113038B/en active
Also Published As
Publication number | Publication date |
---|---|
IT7920770A0 (en) | 1979-03-06 |
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