IT1112581B - ISOKINOLINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents
ISOKINOLINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEMInfo
- Publication number
- IT1112581B IT1112581B IT22150/79A IT2215079A IT1112581B IT 1112581 B IT1112581 B IT 1112581B IT 22150/79 A IT22150/79 A IT 22150/79A IT 2215079 A IT2215079 A IT 2215079A IT 1112581 B IT1112581 B IT 1112581B
- Authority
- IT
- Italy
- Prior art keywords
- isokinoline
- derivatives
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7812026A FR2424270A1 (en) | 1978-04-24 | 1978-04-24 | 4,5-Di:hydro-2-imidazolyl-amino-isoquinoline derivs. - useful as antihypertensives having low toxicity and free from sedative side effects |
FR7904004A FR2449087A2 (en) | 1979-02-16 | 1979-02-16 | 4,5-Di:hydro-2-imidazolyl-amino-isoquinoline derivs. - useful as antihypertensives having low toxicity and free from sedative side effects |
Publications (2)
Publication Number | Publication Date |
---|---|
IT7922150A0 IT7922150A0 (en) | 1979-04-24 |
IT1112581B true IT1112581B (en) | 1986-01-20 |
Family
ID=26220560
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22150/79A IT1112581B (en) | 1978-04-24 | 1979-04-24 | ISOKINOLINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
Country Status (10)
Country | Link |
---|---|
AU (1) | AU4621979A (en) |
DE (1) | DE2916577A1 (en) |
DK (1) | DK166979A (en) |
ES (2) | ES479878A1 (en) |
GB (1) | GB2020280B (en) |
IT (1) | IT1112581B (en) |
LU (1) | LU81182A1 (en) |
NL (1) | NL7902993A (en) |
NZ (1) | NZ190245A (en) |
SE (1) | SE7903554L (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW397812B (en) * | 1995-02-11 | 2000-07-11 | Astra Ab | Bicyclic isothiourea derivatives useful in therapy |
US7217722B2 (en) * | 2000-02-01 | 2007-05-15 | Kirin Beer Kabushiki Kaisha | Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same |
US7074805B2 (en) | 2002-02-20 | 2006-07-11 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
US6933311B2 (en) | 2003-02-11 | 2005-08-23 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
EP2054390B1 (en) | 2006-08-25 | 2012-04-11 | Abbott Laboratories | Indazole derivatives that inhibit trpv1 and uses thereof |
JP2010513557A (en) | 2006-12-20 | 2010-04-30 | アボット・ラボラトリーズ | N- (5,6,7,8-tetrahydronaphthalen-1-yl) urea derivatives and related compounds as TRPV1 vanilloid receptor antagonists for the treatment of pain |
EP2489660A1 (en) | 2008-03-20 | 2012-08-22 | Abbott Laboratories | Methods for making central nervous system agents that are TRPV1 antagonists |
-
1979
- 1979-04-17 NL NL7902993A patent/NL7902993A/en not_active Application Discontinuation
- 1979-04-20 AU AU46219/79A patent/AU4621979A/en not_active Abandoned
- 1979-04-20 NZ NZ190245A patent/NZ190245A/en unknown
- 1979-04-20 GB GB7913821A patent/GB2020280B/en not_active Expired
- 1979-04-23 SE SE7903554A patent/SE7903554L/en not_active Application Discontinuation
- 1979-04-23 LU LU81182A patent/LU81182A1/en unknown
- 1979-04-23 DK DK166979A patent/DK166979A/en active IP Right Grant
- 1979-04-24 DE DE19792916577 patent/DE2916577A1/en not_active Withdrawn
- 1979-04-24 ES ES479878A patent/ES479878A1/en not_active Expired
- 1979-04-24 IT IT22150/79A patent/IT1112581B/en active
- 1979-06-29 ES ES482070A patent/ES482070A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE2916577A1 (en) | 1979-10-31 |
DK166979A (en) | 1979-10-25 |
IT7922150A0 (en) | 1979-04-24 |
SE7903554L (en) | 1979-10-25 |
GB2020280A (en) | 1979-11-14 |
ES482070A1 (en) | 1980-04-01 |
AU4621979A (en) | 1979-11-01 |
GB2020280B (en) | 1982-07-28 |
ES479878A1 (en) | 1980-08-16 |
NZ190245A (en) | 1981-03-16 |
LU81182A1 (en) | 1979-11-07 |
NL7902993A (en) | 1979-10-26 |
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