IT1104165B - Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defects - Google Patents
Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defectsInfo
- Publication number
- IT1104165B IT1104165B IT4790078A IT4790078A IT1104165B IT 1104165 B IT1104165 B IT 1104165B IT 4790078 A IT4790078 A IT 4790078A IT 4790078 A IT4790078 A IT 4790078A IT 1104165 B IT1104165 B IT 1104165B
- Authority
- IT
- Italy
- Prior art keywords
- carnitine
- compsn
- hyperlipaemia
- hypercholesterolaemia
- racemate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Compsns. contain D,L-carnitine, D-carnitine, L-carnitine or their salts, esters or amides in an effective quantity to reestablish normal metabolism and a pharmaceutical vehicle or support. Unlike known compsns. the present compsn. is free from undesirable side-effects. The compsns. are administered orally or parenterally in daily doses of 10-50 mg/kg of active cpd. Animal tests and clinical trials are described.
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT4790078A IT1104165B (en) | 1978-02-03 | 1978-02-03 | Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defects |
DE19792903579 DE2903579A1 (en) | 1978-02-03 | 1979-01-31 | USE OF ACETYL CARNITINE AND OTHER ACYLDER DERIVATIVES OF CARNITINE FOR THE TREATMENT OF HYPERLIPOPROTEINEMIC AND HYPERLIMPIDAEMIA AND MEDICINAL PRODUCTS |
DE2903558A DE2903558C2 (en) | 1978-02-03 | 1979-01-31 | Use of L-carnitine |
ZA79449A ZA79449B (en) | 1978-02-03 | 1979-02-02 | Therapeutic method for the treatment of hyperlipoproteinaemias and hyperlipodaemias |
GB7903650A GB2013496B (en) | 1978-02-03 | 1979-02-02 | Treating hyperlipoproteinaemias and hyperlipidaemias |
BE193254A BE873915A (en) | 1978-02-03 | 1979-02-02 | USE OF ACETYL CARNITINE AND OTHER ACYL CARNITINE DERIVATIVES IN THE TREATMENT OF HYPERLIPOPROTEINEMIA AND HYPERLIPIDEMIA |
GB7903649A GB2013495A (en) | 1978-02-03 | 1979-02-02 | Therapeutic method for the treatment of hyperlipodaemias and hyperlipoproteinaemias |
BE193251A BE873912A (en) | 1978-02-03 | 1979-02-02 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HYPERLIPOIDEMIA AND HYPERLIPOPROTEINEMIA |
NL7900872A NL7900872A (en) | 1978-02-03 | 1979-02-02 | METHOD OF TREATING HYPERLIPOPROTEINEMIA AND HYPERLIPIDEMIA. |
NL7900871A NL7900871A (en) | 1978-02-03 | 1979-02-02 | PROCEDURE FOR THE THERAPEUTIC TREATMENT OF HYPERLIPIDEMIA AND HYPERLIPI PROTEINEMIA. |
CH106179A CH640413A5 (en) | 1978-02-03 | 1979-02-02 | PHARMACEUTICAL PREPARATION FOR THE TREATMENT OF HYPERLIPOPROTEINEMIE. |
ZA79450A ZA79450B (en) | 1978-02-03 | 1979-02-02 | Use of acetyl carnitine and other acyl derivatives of carnitine for treating hyperlipoproteinaemias and hyperlipidaemias |
CA000320784A CA1136551A (en) | 1978-02-03 | 1979-02-02 | Composition containing acetyl carnitine and other acyl derivatives of carnitine for treating hyperlipoproteinaemias and hyperlipidaemias |
CH106279A CH640414A5 (en) | 1978-02-03 | 1979-02-02 | THERAPEUTIC PREPARATION FOR THE TREATMENT OF HYPERLIPOPROTEINEMIE, DYSLIPEMIA AND RELATED DISEASES. |
JP1171679A JPS54113409A (en) | 1978-02-03 | 1979-02-03 | Treating agent for hyperlipoid disease |
JP1171779A JPS54113442A (en) | 1978-02-03 | 1979-02-03 | Treating agent of hyperlipoid disease |
US06/083,418 US4255449A (en) | 1978-02-03 | 1979-10-10 | Method of treating abnormal lipoprote in ratios |
US06/165,351 US4268524A (en) | 1978-02-03 | 1980-07-02 | Method of treating abnormal lipoprotein ratios with acylcarnitine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT4790078A IT1104165B (en) | 1978-02-03 | 1978-02-03 | Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defects |
Publications (2)
Publication Number | Publication Date |
---|---|
IT7847900A0 IT7847900A0 (en) | 1978-02-03 |
IT1104165B true IT1104165B (en) | 1985-10-21 |
Family
ID=11263225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT4790078A IT1104165B (en) | 1978-02-03 | 1978-02-03 | Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defects |
Country Status (3)
Country | Link |
---|---|
BE (2) | BE873912A (en) |
IT (1) | IT1104165B (en) |
ZA (2) | ZA79450B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1156769B (en) * | 1978-05-25 | 1987-02-04 | Sigma Tau Ind Farmaceuti | THERAPEUTIC APPLICATION OF CARNITINE AND OTHER ACIL DERIVATIVES OF CARNITINE |
-
1978
- 1978-02-03 IT IT4790078A patent/IT1104165B/en active
-
1979
- 1979-02-02 ZA ZA79450A patent/ZA79450B/en unknown
- 1979-02-02 BE BE193251A patent/BE873912A/en not_active IP Right Cessation
- 1979-02-02 ZA ZA79449A patent/ZA79449B/en unknown
- 1979-02-02 BE BE193254A patent/BE873915A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IT7847900A0 (en) | 1978-02-03 |
BE873915A (en) | 1979-05-29 |
ZA79450B (en) | 1980-02-27 |
ZA79449B (en) | 1980-02-27 |
BE873912A (en) | 1979-05-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19961216 |