IT1156739B - Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defects - Google Patents
Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defectsInfo
- Publication number
- IT1156739B IT1156739B IT4935378A IT4935378A IT1156739B IT 1156739 B IT1156739 B IT 1156739B IT 4935378 A IT4935378 A IT 4935378A IT 4935378 A IT4935378 A IT 4935378A IT 1156739 B IT1156739 B IT 1156739B
- Authority
- IT
- Italy
- Prior art keywords
- carnitine
- compsn
- hyperlipaemia
- hypercholesterolaemia
- racemate
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
- 208000035150 Hypercholesterolemia Diseases 0.000 title 1
- 208000031226 Hyperlipidaemia Diseases 0.000 title 1
- 229960004203 carnitine Drugs 0.000 title 1
- 230000007547 defect Effects 0.000 title 1
- 230000037356 lipid metabolism Effects 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
- PHIQHXFUZVPYII-LURJTMIESA-N (S)-carnitine Chemical compound C[N+](C)(C)C[C@@H](O)CC([O-])=O PHIQHXFUZVPYII-LURJTMIESA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- PHIQHXFUZVPYII-UHFFFAOYSA-N carnitine Chemical compound C[N+](C)(C)CC(O)CC([O-])=O PHIQHXFUZVPYII-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Compsns. contain D,L-carnitine, D-carnitine, L-carnitine or their salts, esters or amides in an effective quantity to reestablish normal metabolism and a pharmaceutical vehicle or support. Unlike known compsns. the present compsn. is free from undesirable side-effects. The compsns. are administered orally or parenterally in daily doses of 10-50 mg/kg of active cpd. Animal tests and clinical trials are described.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT4935378A IT1156739B (en) | 1978-05-15 | 1978-05-15 | Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defects |
DE2903558A DE2903558C2 (en) | 1978-02-03 | 1979-01-31 | Use of L-carnitine |
GB7903649A GB2013495A (en) | 1978-02-03 | 1979-02-02 | Therapeutic method for the treatment of hyperlipodaemias and hyperlipoproteinaemias |
CH106279A CH640414A5 (en) | 1978-02-03 | 1979-02-02 | THERAPEUTIC PREPARATION FOR THE TREATMENT OF HYPERLIPOPROTEINEMIE, DYSLIPEMIA AND RELATED DISEASES. |
NL7900871A NL7900871A (en) | 1978-02-03 | 1979-02-02 | PROCEDURE FOR THE THERAPEUTIC TREATMENT OF HYPERLIPIDEMIA AND HYPERLIPI PROTEINEMIA. |
JP1171679A JPS54113409A (en) | 1978-02-03 | 1979-02-03 | Treating agent for hyperlipoid disease |
US06/083,418 US4255449A (en) | 1978-02-03 | 1979-10-10 | Method of treating abnormal lipoprote in ratios |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT4935378A IT1156739B (en) | 1978-05-15 | 1978-05-15 | Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defects |
Publications (2)
Publication Number | Publication Date |
---|---|
IT7849353A0 IT7849353A0 (en) | 1978-05-15 |
IT1156739B true IT1156739B (en) | 1987-02-04 |
Family
ID=11270444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT4935378A IT1156739B (en) | 1978-02-03 | 1978-05-15 | Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defects |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1156739B (en) |
-
1978
- 1978-05-15 IT IT4935378A patent/IT1156739B/en active
Also Published As
Publication number | Publication date |
---|---|
IT7849353A0 (en) | 1978-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970416 |