IT1094003B - PROCEDURE FOR PRODUCING MAITANSINOL AND ITS DERIVATIVES - Google Patents

PROCEDURE FOR PRODUCING MAITANSINOL AND ITS DERIVATIVES

Info

Publication number
IT1094003B
IT1094003B IT21819/78A IT2181978A IT1094003B IT 1094003 B IT1094003 B IT 1094003B IT 21819/78 A IT21819/78 A IT 21819/78A IT 2181978 A IT2181978 A IT 2181978A IT 1094003 B IT1094003 B IT 1094003B
Authority
IT
Italy
Prior art keywords
maitansinol
derivatives
procedure
producing
producing maitansinol
Prior art date
Application number
IT21819/78A
Other languages
Italian (it)
Other versions
IT7821819A0 (en
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of IT7821819A0 publication Critical patent/IT7821819A0/en
Application granted granted Critical
Publication of IT1094003B publication Critical patent/IT1094003B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT21819/78A 1977-03-31 1978-03-30 PROCEDURE FOR PRODUCING MAITANSINOL AND ITS DERIVATIVES IT1094003B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52037167A JPS6010718B2 (en) 1977-03-31 1977-03-31 Process for producing maytansinol, maytanacin and maytansinol propionate

Publications (2)

Publication Number Publication Date
IT7821819A0 IT7821819A0 (en) 1978-03-30
IT1094003B true IT1094003B (en) 1985-07-26

Family

ID=12490032

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21819/78A IT1094003B (en) 1977-03-31 1978-03-30 PROCEDURE FOR PRODUCING MAITANSINOL AND ITS DERIVATIVES

Country Status (20)

Country Link
JP (1) JPS6010718B2 (en)
AT (1) AT362058B (en)
AU (1) AU507869B2 (en)
CA (1) CA1092999A (en)
CH (1) CH631740A5 (en)
CS (1) CS214881B2 (en)
DE (1) DE2746253C2 (en)
DK (1) DK143570C (en)
ES (1) ES463206A1 (en)
FR (1) FR2385798A1 (en)
GB (1) GB1554395A (en)
HU (1) HU177391B (en)
IE (1) IE45888B1 (en)
IT (1) IT1094003B (en)
NL (1) NL7711273A (en)
PL (1) PL108863B1 (en)
PT (1) PT67853B (en)
SE (1) SE7711543L (en)
SU (1) SU938746A3 (en)
YU (1) YU243777A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6016236B2 (en) * 1977-11-18 1985-04-24 武田薬品工業株式会社 Production method of antibiotic C-15003 P-3
JPS6010720B2 (en) * 1977-11-18 1985-03-19 武田薬品工業株式会社 Production method of antibiotic C-15003 P-4
JPS55162791A (en) * 1979-06-05 1980-12-18 Takeda Chem Ind Ltd Antibiotic c-15003pnd and its preparation
EP0028683A1 (en) * 1979-09-21 1981-05-20 Takeda Chemical Industries, Ltd. Antibiotic C-15003 PHO and production thereof
US6573074B2 (en) * 2000-04-12 2003-06-03 Smithkline Beecham Plc Methods for ansamitocin production
US6333410B1 (en) 2000-08-18 2001-12-25 Immunogen, Inc. Process for the preparation and purification of thiol-containing maytansinoids
US7432088B2 (en) 2003-05-08 2008-10-07 Immunogen Inc. Methods for the production of ansamitocins
CN116239607B (en) * 2023-01-04 2024-04-09 山东大学 Maytansine derivative and biosynthesis method and application thereof

Also Published As

Publication number Publication date
CH631740A5 (en) 1982-08-31
PL201539A1 (en) 1978-09-25
DE2746253C2 (en) 1986-08-21
JPS6010718B2 (en) 1985-03-19
HU177391B (en) 1981-09-28
AU507869B2 (en) 1980-02-28
SE7711543L (en) 1978-10-01
ES463206A1 (en) 1978-08-16
PT67853B (en) 1980-05-05
YU243777A (en) 1982-06-30
AT362058B (en) 1981-04-27
NL7711273A (en) 1978-10-03
DK143570B (en) 1981-09-07
IE45888B1 (en) 1982-12-29
DK458977A (en) 1978-10-01
FR2385798A1 (en) 1978-10-27
ATA736377A (en) 1980-09-15
SU938746A3 (en) 1982-06-23
IE45888L (en) 1978-09-30
GB1554395A (en) 1979-10-17
DE2746253A1 (en) 1978-10-05
PT67853A (en) 1978-04-01
JPS53121998A (en) 1978-10-24
DK143570C (en) 1982-02-08
PL108863B1 (en) 1980-05-31
CS214881B2 (en) 1982-06-25
IT7821819A0 (en) 1978-03-30
CA1092999A (en) 1981-01-06
AU2907377A (en) 1979-03-29
FR2385798B1 (en) 1980-04-25

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970326