IT1090782B - 2 4 bifenilil 2 dietilamino alchil propionamide suoi sali e procedimenti di fabbricazione relativi - Google Patents

2 4 bifenilil 2 dietilamino alchil propionamide suoi sali e procedimenti di fabbricazione relativi

Info

Publication number
IT1090782B
IT1090782B IT964377A IT964377A IT1090782B IT 1090782 B IT1090782 B IT 1090782B IT 964377 A IT964377 A IT 964377A IT 964377 A IT964377 A IT 964377A IT 1090782 B IT1090782 B IT 1090782B
Authority
IT
Italy
Prior art keywords
biphenylil
alchyl
diethylamin
propionamide
salts
Prior art date
Application number
IT964377A
Other languages
English (en)
Italian (it)
Inventor
Alberto Meli
Claudio Bianchini
Soldato Pieropdel
Mario Gherardoni
Vittorio Pestellini
Giovanna Volterra
Original Assignee
Menarini Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Sas filed Critical Menarini Sas
Priority to IT964377A priority Critical patent/IT1090782B/it
Priority to DE19782851416 priority patent/DE2851416A1/de
Priority to CH1216178A priority patent/CH637370A5/it
Priority to NL7811698A priority patent/NL7811698A/nl
Priority to ES475533A priority patent/ES475533A1/es
Priority to JP14730778A priority patent/JPS5490157A/ja
Priority to FR7833889A priority patent/FR2410641A1/fr
Priority to CA000317175A priority patent/CA1118446A/en
Priority to BE192036A priority patent/BE872403A/xx
Application granted granted Critical
Publication of IT1090782B publication Critical patent/IT1090782B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT964377A 1977-11-30 1977-11-30 2 4 bifenilil 2 dietilamino alchil propionamide suoi sali e procedimenti di fabbricazione relativi IT1090782B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT964377A IT1090782B (it) 1977-11-30 1977-11-30 2 4 bifenilil 2 dietilamino alchil propionamide suoi sali e procedimenti di fabbricazione relativi
DE19782851416 DE2851416A1 (de) 1977-11-30 1978-11-28 2-(4-biphenylyl)-n-(diethylaminoalkyl)- propionamide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
CH1216178A CH637370A5 (en) 1977-11-30 1978-11-28 Racemic forms and optically active forms of 2-(4-biphenylyl)-N-(diethylaminoalkyl)-propionamide, salts thereof and relative preparation processes
NL7811698A NL7811698A (nl) 1977-11-30 1978-11-29 Racemische en optisch actieve 2-(4-bifenylyl)-n- (diethylaminoalkyl) propionamiden en de zouten daarvan.
ES475533A ES475533A1 (es) 1977-11-30 1978-11-29 Un metodo para la preparacion de formas racemicas y optica- mente activas de 2-(4-difenilil)-n-(dimetilamino-alquil)pro-pionamida
JP14730778A JPS5490157A (en) 1977-11-30 1978-11-30 Novel propione amide derivative and its manufacture
FR7833889A FR2410641A1 (fr) 1977-11-30 1978-11-30 Formes racemiques et optiquement actives de (biphenylyl-4)-2 n-(diethylamino alkyl) propionamides et de leurs sels utiles comme agents spasmolytiques et procedes de preparation
CA000317175A CA1118446A (en) 1977-11-30 1978-11-30 Racemic forms and optically active forms of 2-(4-biphenylyl)-n-(diethylamino alkyl) propionamide and salts thereof as well as processes for their production and use as spasmoltyic agents
BE192036A BE872403A (fr) 1977-11-30 1978-11-30 Formes racemiques et formes optiquement actives de 2-(4-bi-phenylyl)-n-(diethylaminoalcoyl)-propionamide, leurs sels, leur preparation et leur utilisation comme agents spasmolytiques

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT964377A IT1090782B (it) 1977-11-30 1977-11-30 2 4 bifenilil 2 dietilamino alchil propionamide suoi sali e procedimenti di fabbricazione relativi

Publications (1)

Publication Number Publication Date
IT1090782B true IT1090782B (it) 1985-06-26

Family

ID=11132874

Family Applications (1)

Application Number Title Priority Date Filing Date
IT964377A IT1090782B (it) 1977-11-30 1977-11-30 2 4 bifenilil 2 dietilamino alchil propionamide suoi sali e procedimenti di fabbricazione relativi

Country Status (9)

Country Link
JP (1) JPS5490157A (nl)
BE (1) BE872403A (nl)
CA (1) CA1118446A (nl)
CH (1) CH637370A5 (nl)
DE (1) DE2851416A1 (nl)
ES (1) ES475533A1 (nl)
FR (1) FR2410641A1 (nl)
IT (1) IT1090782B (nl)
NL (1) NL7811698A (nl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20012025A1 (it) * 2001-09-28 2003-03-28 Dompe Spa Sali di ammonio quaternari di omega-amminoalchilammidi di acidi r 2-aril-propionici e composizioni farmaceutiche che li contengono
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
ES2559781T3 (es) * 2006-08-08 2016-02-15 Techfields Biochem Co. Ltd Profármacos de ácidos aril- y heteroarilacéticos solubles en agua y con carga positiva con una tasa de penetración en piel muy rápida
AU2006347391B2 (en) * 2006-08-15 2013-03-07 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate
AU2013206218B2 (en) * 2006-08-15 2016-06-30 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate
US9371284B2 (en) 2007-06-04 2016-06-21 Techfields Pharma Co., Ltd. Pro-drugs of NSAIAS with very high skin and membranes penetration rates and their new medicinal uses
KR20230085223A (ko) 2008-12-04 2023-06-13 충시 위 고투과력을 가진 조성물 및 이의 적용
JP5940036B2 (ja) * 2013-10-08 2016-06-29 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ
JP6290947B2 (ja) * 2016-02-05 2018-03-07 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1584547A (nl) * 1968-06-05 1969-12-26
FR1593024A (nl) * 1968-09-18 1970-05-25
FR2119846A1 (en) * 1970-12-28 1972-08-11 Choay Sa N,n-diethylaminoethylamide of para isobutyl phenylacetic - acid - antiinflammatory and analgesic
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds

Also Published As

Publication number Publication date
NL7811698A (nl) 1979-06-01
ES475533A1 (es) 1980-01-16
FR2410641A1 (fr) 1979-06-29
JPS631286B2 (nl) 1988-01-12
CH637370A5 (en) 1983-07-29
JPS5490157A (en) 1979-07-17
CA1118446A (en) 1982-02-16
FR2410641B1 (nl) 1983-04-15
DE2851416C2 (nl) 1989-02-23
BE872403A (fr) 1979-03-16
DE2851416A1 (de) 1979-05-31

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