IT1056733B - 4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazione - Google Patents
4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazioneInfo
- Publication number
- IT1056733B IT1056733B IT2811573A IT2811573A IT1056733B IT 1056733 B IT1056733 B IT 1056733B IT 2811573 A IT2811573 A IT 2811573A IT 2811573 A IT2811573 A IT 2811573A IT 1056733 B IT1056733 B IT 1056733B
- Authority
- IT
- Italy
- Prior art keywords
- reacting
- alkyl
- nr1r2
- obtd
- prod
- Prior art date
Links
- XYVMOLOUBJBNBF-UHFFFAOYSA-N 3h-1,3-oxazol-2-one Chemical compound OC1=NC=CO1 XYVMOLOUBJBNBF-UHFFFAOYSA-N 0.000 title 1
- -1 aryl isocyanate Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- CKDWPUIZGOQOOM-UHFFFAOYSA-N Carbamyl chloride Chemical compound NC(Cl)=O CKDWPUIZGOQOOM-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 230000000994 depressogenic effect Effects 0.000 abstract 1
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- GRHBQAYDJPGGLF-UHFFFAOYSA-N isothiocyanic acid Chemical compound N=C=S GRHBQAYDJPGGLF-UHFFFAOYSA-N 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
- ZWZVWGITAAIFPS-UHFFFAOYSA-N thiophosgene Chemical compound ClC(Cl)=S ZWZVWGITAAIFPS-UHFFFAOYSA-N 0.000 abstract 1
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2811573A IT1056733B (it) | 1973-08-22 | 1973-08-22 | 4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazione |
| US403275A US3930008A (en) | 1972-10-16 | 1973-10-03 | 4-Aryl-5-aminoalkyl-4-oxazolin-2-ones |
| AU61216/73A AU490583B2 (en) | 1973-10-10 | 4-aryl-5-aminoalkyl-4-oxazolin-2-ones | |
| CH1449973A CH605859A5 (it) | 1972-10-16 | 1973-10-11 | |
| GB4787573A GB1429571A (en) | 1972-10-16 | 1973-10-12 | 4-aryl-5-aminoalkyl-4-oxazolin-2ones |
| NL7314147.A NL161154C (nl) | 1972-10-16 | 1973-10-15 | Werkwijze voor het bereiden van een farmaceutisch preparaat, dat een 4-oxazoline-2-on-derivaat bevat, gevormd preparaat en werkwijze voor het bereiden van een verbinding geschikt voor gebruik bij voornoemde werkwijze. |
| ES419632A ES419632A1 (es) | 1972-10-16 | 1973-10-15 | Un procedimiento para preparar una 4-amil-5-aminoguil-4-o- xazolin-2-ona. |
| NO4002/73A NO140299C (no) | 1972-10-16 | 1973-10-15 | Analogifremgangsmaate ved fremstilling av terapeutisk aktive 4-aryl-5-aminoalkyl-4-oksazolin-2-oner |
| FI3183/73A FI57752C (fi) | 1972-10-16 | 1973-10-15 | Foerfarande foer framstaellning av pao centralnervsystemet verkande 4-fenyl-5-amino-etyl-4-oxazolin-2-onderivat eller dess farmaceutiskt godtagbara salter |
| SE7313966A SE391717B (sv) | 1972-10-16 | 1973-10-15 | Forfarande for framstellning av 4-aryl-5-aminoalkyl-4-oxazolin-2-oner |
| CA183,418A CA1016550A (en) | 1972-10-16 | 1973-10-15 | 4-aryl-5-aminoalkyl-4-oxazolin-2-ones |
| JP48116238A JPS4993360A (it) | 1972-10-16 | 1973-10-16 | |
| DK560273AA DK135122B (da) | 1972-10-16 | 1973-10-16 | Analogifremgangsmåde til fremstilling af 4-aryl-5-aminoalkyl-4-oxazolin-2-onderivater. |
| FR7336838A FR2202701B1 (it) | 1972-10-16 | 1973-10-16 | |
| DE19732351948 DE2351948A1 (de) | 1972-10-16 | 1973-10-16 | 4-aryl-5-aminoalkyl-4-oxazolin-2-one, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2811573A IT1056733B (it) | 1973-08-22 | 1973-08-22 | 4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1056733B true IT1056733B (it) | 1982-02-20 |
Family
ID=11222959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT2811573A IT1056733B (it) | 1972-10-16 | 1973-08-22 | 4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazione |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1056733B (it) |
-
1973
- 1973-08-22 IT IT2811573A patent/IT1056733B/it active
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