IT1050135B - Metodo per la produzione di un preparato diagnostico sulla base di macro aggregati di albumina del siero marcati con 99 mtc. - Google Patents
Metodo per la produzione di un preparato diagnostico sulla base di macro aggregati di albumina del siero marcati con 99 mtc.Info
- Publication number
- IT1050135B IT1050135B IT24778/71A IT2477871A IT1050135B IT 1050135 B IT1050135 B IT 1050135B IT 24778/71 A IT24778/71 A IT 24778/71A IT 2477871 A IT2477871 A IT 2477871A IT 1050135 B IT1050135 B IT 1050135B
- Authority
- IT
- Italy
- Prior art keywords
- serum albumin
- mtc
- basis
- production
- composition
- Prior art date
Links
- 102000007562 Serum Albumin Human genes 0.000 title abstract 4
- 108010071390 Serum Albumin Proteins 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 5
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000002285 radioactive effect Effects 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 239000004133 Sodium thiosulphate Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- FYFFGSSZFBZTAH-UHFFFAOYSA-N methylaminomethanetriol Chemical compound CNC(O)(O)O FYFFGSSZFBZTAH-UHFFFAOYSA-N 0.000 abstract 1
- 230000000717 retained effect Effects 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229940074404 sodium succinate Drugs 0.000 abstract 1
- ZDQYSKICYIVCPN-UHFFFAOYSA-L sodium succinate (anhydrous) Chemical compound [Na+].[Na+].[O-]C(=O)CCC([O-])=O ZDQYSKICYIVCPN-UHFFFAOYSA-L 0.000 abstract 1
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 abstract 1
- 235000019345 sodium thiosulphate Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/081—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the protein being an albumin, e.g. human serum albumin [HSA], bovine serum albumin [BSA], ovalbumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1255—Granulates, agglomerates, microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR707018679A FR2088139B1 (enExample) | 1970-05-22 | 1970-05-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1050135B true IT1050135B (it) | 1981-03-10 |
Family
ID=9055931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT24778/71A IT1050135B (it) | 1970-05-22 | 1971-05-19 | Metodo per la produzione di un preparato diagnostico sulla base di macro aggregati di albumina del siero marcati con 99 mtc. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3803299A (enExample) |
| BE (1) | BE767502A (enExample) |
| CA (1) | CA946279A (enExample) |
| CH (1) | CH564350A5 (enExample) |
| DE (1) | DE2124752A1 (enExample) |
| DK (1) | DK130205B (enExample) |
| FR (1) | FR2088139B1 (enExample) |
| GB (1) | GB1318813A (enExample) |
| IT (1) | IT1050135B (enExample) |
| NL (1) | NL7106773A (enExample) |
| ZA (1) | ZA713185B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4024233A (en) * | 1972-06-05 | 1977-05-17 | Medi-Physics, Inc. | 99M-technetium labeled macroaggregated human serum albumin pharmaceutical |
| GB1417003A (en) * | 1972-06-22 | 1975-12-10 | Radiochemical Centre Ltd | Stabilisation of fibrinogen |
| US4002739A (en) * | 1975-02-18 | 1977-01-11 | Warner-Lambert Company | Soluble collagen |
| US4066742A (en) * | 1977-02-14 | 1978-01-03 | Medi-Physics, Inc. | Tc-99m sulfur colloid radiopharmaceuticals |
| US4094965A (en) * | 1977-04-01 | 1978-06-13 | New England Nuclear Corporation | Diagnostic agents containing albumin and method for making same |
| US4411518A (en) * | 1977-09-23 | 1983-10-25 | Gamma Biologicals, Inc. | Apparatus for use in qualitative determination of immunological reactions |
| US4197088A (en) * | 1977-09-23 | 1980-04-08 | Akro-Medic Engineering, Inc. | Method for qualitative and quantitative determination of immunological reactions |
| US4305922A (en) * | 1978-10-04 | 1981-12-15 | University Patents, Inc. | Labeling proteins with 99m-Tc by ligand exchange |
| CH652599A5 (de) * | 1981-08-28 | 1985-11-29 | Solco Basel Ag | Verfahren zur herstellung physiologisch abbaubarer kolloidaler, human-serumalbumin enthaltender produkte und ihre verwendung. |
| US5071965A (en) * | 1988-07-19 | 1991-12-10 | Mallinckrodt Medical, Inc. | Novel tc-99m complexes |
| US5096696A (en) * | 1990-02-05 | 1992-03-17 | The Research Foundation Of State University Of New York | Binding of radiolabeled albumin fragments to fibrin clots |
| CA2370409C (en) * | 1999-03-26 | 2009-02-03 | London Health Sciences Centre | Colloid for scintigraphy |
| US6706251B1 (en) | 1999-03-26 | 2004-03-16 | London Health Sciences Centre | Colloid for scintigraphy |
| US6730286B2 (en) * | 2001-02-28 | 2004-05-04 | Bracco Diagnostics, Inc. | Manufacturing process to control particle size |
| US10793327B2 (en) | 2017-10-09 | 2020-10-06 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
| CN114127501B (zh) | 2019-03-14 | 2023-02-17 | 泰尔茂比司特生物技术有限公司 | 多部分冻干容器及使用方法 |
-
1970
- 1970-05-22 FR FR707018679A patent/FR2088139B1/fr not_active Expired
-
1971
- 1971-05-17 ZA ZA713185A patent/ZA713185B/xx unknown
- 1971-05-18 NL NL7106773A patent/NL7106773A/xx not_active Application Discontinuation
- 1971-05-19 IT IT24778/71A patent/IT1050135B/it active
- 1971-05-19 DE DE19712124752 patent/DE2124752A1/de active Pending
- 1971-05-19 GB GB1576971*[A patent/GB1318813A/en not_active Expired
- 1971-05-19 DK DK244371AA patent/DK130205B/da unknown
- 1971-05-19 CH CH738971A patent/CH564350A5/xx not_active IP Right Cessation
- 1971-05-21 BE BE767502A patent/BE767502A/nl unknown
- 1971-05-21 CA CA113,595A patent/CA946279A/en not_active Expired
- 1971-05-24 US US00146544A patent/US3803299A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2088139A1 (enExample) | 1972-01-07 |
| NL7106773A (enExample) | 1971-11-24 |
| GB1318813A (en) | 1973-05-31 |
| ZA713185B (en) | 1972-01-26 |
| DK130205C (enExample) | 1975-06-16 |
| DE2124752A1 (de) | 1971-12-02 |
| US3803299A (en) | 1974-04-09 |
| DK130205B (da) | 1975-01-20 |
| CA946279A (en) | 1974-04-30 |
| BE767502A (nl) | 1971-11-22 |
| FR2088139B1 (enExample) | 1973-06-08 |
| CH564350A5 (enExample) | 1975-07-31 |
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