IT1047895B - 1,3-benzodioxol-2-yl alkanoic acid and amide derivs - -antiinflammatories, analgesics, antipyretics, antitussives, cns-depr - Google Patents
1,3-benzodioxol-2-yl alkanoic acid and amide derivs - -antiinflammatories, analgesics, antipyretics, antitussives, cns-deprInfo
- Publication number
- IT1047895B IT1047895B IT3245872A IT3245872A IT1047895B IT 1047895 B IT1047895 B IT 1047895B IT 3245872 A IT3245872 A IT 3245872A IT 3245872 A IT3245872 A IT 3245872A IT 1047895 B IT1047895 B IT 1047895B
- Authority
- IT
- Italy
- Prior art keywords
- alkyl
- alk
- opt
- substd
- halo
- Prior art date
Links
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel title cpds. have formula: (where R=H, lower-alkyl (opt. substd. by halo or hydroxy), aryl, aralkyl (opt. ring substd. by halo, alkyl, hydroxy or alkoxy) Alk=straight, branched or cyclic opt. unsaturated alkyl or R may be joined to Alk to form a spiran cpd. R1 = H, halo, opt. halosubstd. lower alkyl, hydroxy, nitro, opt. substd. amino or may represent a benzene ring condensed with benzodioxole ring R2 = -OR3 or -NR4R5 R3 = H, straight or branched alkyl, hydroxyalkyl, aralkyl, aminoalkyl, aminoalkoxyalkyl (the amine gp. being free, mono- or di-substd. by lower alkyl gps. or forming part of a heterocyclic gp.) R4, R5 = same or different H, straight, branched or cyclic lower alkyl, hydroxyalkyl, aralkyl, aminoalkyl (in which the amine gp. is free, mono- or di-substd. by alkyl gps.) or may form part of a heterocyclic ring), hydroxy, acyloxy, aryl (opt. substd. by halo or alkyl gps.) or together with the N atom form a heterocyclic ring with the conditions that (a) when R = CH3 and R1 = H or 5-CH3, Alk COR2 is not carboxymethyl, 2-carboxyethyl, 1-methyl-2-carboxyethyl, 2-carboxy-propyl or the corresponding ethylesters (b) when R = CH3 and R1 = 5-NO2 Alk COR2 is not carboxymethyl or the corresponding ethyl ester (c) when R = phenyl and R1=h Alk cor2 is not carboxymethyl or carbomethyoxymethyl and (d) when R and R1 = H the Alk-CO-R2 is not -CH2CONH2) including their salts and stereocoomers.
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE795248D BE795248A (en) | 1972-02-09 | BENZODIOXOL SUBSTITUTES AND THEIR PREPARATION | |
IT3245872A IT1047895B (en) | 1972-12-04 | 1972-12-04 | 1,3-benzodioxol-2-yl alkanoic acid and amide derivs - -antiinflammatories, analgesics, antipyretics, antitussives, cns-depr |
US05/328,633 US3969368A (en) | 1972-02-09 | 1973-02-01 | 2-Substituted benzodioxoles |
AU51650/73A AU472956B2 (en) | 1972-02-09 | 1973-02-01 | Substituted benzodioxoles |
GB589973A GB1425501A (en) | 1972-02-09 | 1973-02-06 | Substituted benzodioxoles |
DE19732306289 DE2306289C3 (en) | 1972-02-09 | 1973-02-08 | 13-Benzodioxole derivatives and pharmaceuticals containing them |
FR7304533A FR2181715B1 (en) | 1972-02-09 | 1973-02-08 | |
NL7301837A NL7301837A (en) | 1972-02-09 | 1973-02-09 | |
JP48016351A JPS5145596B2 (en) | 1972-02-09 | 1973-02-09 | |
CA163,331A CA1016942A (en) | 1972-02-09 | 1973-02-09 | 2-substituted benzodioxoles |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT3245872A IT1047895B (en) | 1972-12-04 | 1972-12-04 | 1,3-benzodioxol-2-yl alkanoic acid and amide derivs - -antiinflammatories, analgesics, antipyretics, antitussives, cns-depr |
Publications (1)
Publication Number | Publication Date |
---|---|
IT1047895B true IT1047895B (en) | 1980-10-20 |
Family
ID=11235402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT3245872A IT1047895B (en) | 1972-02-09 | 1972-12-04 | 1,3-benzodioxol-2-yl alkanoic acid and amide derivs - -antiinflammatories, analgesics, antipyretics, antitussives, cns-depr |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1047895B (en) |
-
1972
- 1972-12-04 IT IT3245872A patent/IT1047895B/en active
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