IT1026755B - O,O-dimethyl-dithiophosphoryl-acetic acid N-monomethylamide - obtd from O,O-dimethyldithiophosphate, reaction with methyl-2-chloroacetate, then monomethylamine - Google Patents
O,O-dimethyl-dithiophosphoryl-acetic acid N-monomethylamide - obtd from O,O-dimethyldithiophosphate, reaction with methyl-2-chloroacetate, then monomethylamineInfo
- Publication number
- IT1026755B IT1026755B IT3013774A IT3013774A IT1026755B IT 1026755 B IT1026755 B IT 1026755B IT 3013774 A IT3013774 A IT 3013774A IT 3013774 A IT3013774 A IT 3013774A IT 1026755 B IT1026755 B IT 1026755B
- Authority
- IT
- Italy
- Prior art keywords
- dimethyl
- reacted
- degrees
- acetic acid
- dithiophosphoryl
- Prior art date
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
O,O-dimethyl-dithiophosphoryl acetic acid N-mono-methylamide (I) is prepd. by reacting phosphorosulphides with methanol in toluene to give O,O-dimethyl-dithiophosphoric acid (II) which is reacted with aq. alkali metal hydroxides or -carbonates to form the salts. The soln. is then reacted with 2- chloroacetic acid methyl ester (III) at pH 5.5-7 and 80-100 degrees for 10-15 min. and the product is purified by steam-distn. at 60-65 degrees at a reduced pressure of 140-150 mm Hg, the vol. ratio steam : ester being (0-25:1). The methylester obtained (IV) is reacted with aq. methylamine at 0-10 degrees C in the presence of a surface-active agent whereby a part of the slurry contg. (I) is refluxed back to the reactor. (I) is a known cpd. with insecticidal activity. The process may be continuous giving high yields of very high purity.
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT3013774A IT1026755B (en) | 1974-12-03 | 1974-12-03 | O,O-dimethyl-dithiophosphoryl-acetic acid N-monomethylamide - obtd from O,O-dimethyldithiophosphate, reaction with methyl-2-chloroacetate, then monomethylamine |
DE19752500452 DE2500452A1 (en) | 1974-01-11 | 1975-01-08 | IMPROVED CONTINUOUS PROCESS FOR THE PREPARATION OF N-MONOMETHYLAMIDE OF O, O-DIMETHYL-DITHIO-PHOSPHORIC ACID ACID AS AN INSECTICIDE |
BR7500135A BR7500135A (en) | 1974-01-11 | 1975-01-09 | CONTINUOUS PROCESS FOR THE PREPARATION OF N-MONOMETHYLAMIDE FROM O-DIMETHYL-DITIOPHOSPHORYL ACETIC ACID |
DD18356975A DD118434A5 (en) | 1974-01-11 | 1975-01-09 | |
ES433697A ES433697A1 (en) | 1974-01-11 | 1975-01-10 | Preparation of the n-monomethylamide of 0,0-dimethyl-dithiophosphorylacetic acid |
JP506275A JPS5736915B2 (en) | 1974-01-11 | 1975-01-10 | |
FR7500649A FR2257597B1 (en) | 1974-01-11 | 1975-01-10 | |
GB136775A GB1485585A (en) | 1974-01-11 | 1975-01-13 | Preparation of the n-monomethylamide of 0,0-dimethyl-dithiophosphorylacetic acid |
US05/741,990 US4083900A (en) | 1974-12-03 | 1976-11-15 | Continuous process for the preparation of N-monomethylamide of O,O-dimethyl-dithiophosphoryl acetic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT3013774A IT1026755B (en) | 1974-12-03 | 1974-12-03 | O,O-dimethyl-dithiophosphoryl-acetic acid N-monomethylamide - obtd from O,O-dimethyldithiophosphate, reaction with methyl-2-chloroacetate, then monomethylamine |
Publications (1)
Publication Number | Publication Date |
---|---|
IT1026755B true IT1026755B (en) | 1978-10-20 |
Family
ID=11229191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT3013774A IT1026755B (en) | 1974-01-11 | 1974-12-03 | O,O-dimethyl-dithiophosphoryl-acetic acid N-monomethylamide - obtd from O,O-dimethyldithiophosphate, reaction with methyl-2-chloroacetate, then monomethylamine |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1026755B (en) |
-
1974
- 1974-12-03 IT IT3013774A patent/IT1026755B/en active
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