IS8404A - Nogo-A binding með aukinni sækni og lyfjafræðilegnotkun hennar - Google Patents
Nogo-A binding með aukinni sækni og lyfjafræðilegnotkun hennarInfo
- Publication number
- IS8404A IS8404A IS8404A IS8404A IS8404A IS 8404 A IS8404 A IS 8404A IS 8404 A IS8404 A IS 8404A IS 8404 A IS8404 A IS 8404A IS 8404 A IS8404 A IS 8404A
- Authority
- IS
- Iceland
- Prior art keywords
- nogo
- binding
- increased affinity
- pharmacological use
- pharmacological
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0321997.9A GB0321997D0 (en) | 2003-09-19 | 2003-09-19 | Organic compound |
| PCT/EP2004/010489 WO2005028508A2 (en) | 2003-09-19 | 2004-09-17 | Nogo-a binding with enhanced affinity and pharmaceutical use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS8404A true IS8404A (is) | 2006-04-10 |
Family
ID=29266310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS8404A IS8404A (is) | 2003-09-19 | 2006-04-10 | Nogo-A binding með aukinni sækni og lyfjafræðilegnotkun hennar |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US20090181023A1 (is) |
| EP (3) | EP1668033A2 (is) |
| JP (1) | JP2007527232A (is) |
| KR (1) | KR20060119982A (is) |
| CN (1) | CN1878792A (is) |
| AR (1) | AR045671A1 (is) |
| AU (2) | AU2004274164B2 (is) |
| BR (1) | BRPI0414174B8 (is) |
| CA (1) | CA2538725C (is) |
| CO (1) | CO5680457A2 (is) |
| EC (1) | ECSP066431A (is) |
| GB (1) | GB0321997D0 (is) |
| IL (2) | IL174145A (is) |
| IS (1) | IS8404A (is) |
| MA (1) | MA28088A1 (is) |
| MY (2) | MY161068A (is) |
| NO (1) | NO20061678L (is) |
| NZ (1) | NZ545679A (is) |
| PE (1) | PE20050949A1 (is) |
| RU (1) | RU2380377C2 (is) |
| SG (1) | SG146660A1 (is) |
| TN (1) | TNSN06085A1 (is) |
| TW (1) | TWI372060B (is) |
| WO (1) | WO2005028508A2 (is) |
| ZA (1) | ZA200601842B (is) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2362780C2 (ru) * | 2003-12-22 | 2009-07-27 | Глаксо Груп Лимитед | Nogo-a-нейтрализующие иммуноглобулины для лечения неврологических заболеваний |
| SG157418A1 (en) * | 2004-12-01 | 2009-12-29 | Univ Singapore | Nogo a protein fragments as neuronal network- interacting peptides |
| EP1899377B1 (en) * | 2005-07-05 | 2012-08-22 | Glaxo Group Limited | Humanised antibodies specific for nogo-a and phrarmaceutical uses thereof |
| GB0525662D0 (en) | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Immunoglobulins |
| NZ584911A (en) | 2007-11-02 | 2011-08-26 | Novartis Ag | Improved nogo-a binding molecules and pharmaceutical use thereof |
| WO2012004773A1 (en) | 2010-07-09 | 2012-01-12 | Universite De Geneve | New uses of nogo-a inhibitors and related methods |
| WO2014006105A1 (en) | 2012-07-05 | 2014-01-09 | Glaxo Group Limited | Optimum dose regime of an anti-nogo-a antibody in the treatment of amyotrophic lateral sclerosis |
| CN113527462B (zh) * | 2020-04-22 | 2023-05-23 | 北京大学 | 一种具有镇痛作用的小分子肽及其特异性抗体 |
| CN114470197B (zh) * | 2022-02-16 | 2023-10-03 | 天津长和生物技术有限公司 | 低氧培养的hUCMSC联合NogoA抗体在脊髓损伤治疗中的应用 |
| WO2024041450A1 (zh) * | 2022-08-22 | 2024-02-29 | 舒泰神（北京）生物制药股份有限公司 | 特异性识别Nogo-A的抗体及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308573D0 (en) | 1983-03-29 | 1983-05-05 | British Nuclear Fuels Ltd | Filament impregnating/coating |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| DE3785186T2 (de) | 1986-09-02 | 1993-07-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| JP2904918B2 (ja) | 1989-02-13 | 1999-06-14 | シェーリング アクチェンゲゼルシャフト | 新規血栓溶解剤 |
| DK1098972T3 (da) * | 1998-07-22 | 2011-01-03 | Smithkline Beecham Ltd | Protein med lighed med neuroendokrinspecifikt protein samt cDNA kodende derfor |
| AU784349C (en) * | 2000-01-12 | 2006-09-28 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| CA2468733C (en) * | 2001-11-30 | 2013-06-11 | Biogen Idec Ma Inc. | Antibodies against monocyte chemotactic proteins |
| GB0228832D0 (en) * | 2002-12-10 | 2003-01-15 | Novartis Ag | Organic compound |
| RU2362780C2 (ru) * | 2003-12-22 | 2009-07-27 | Глаксо Груп Лимитед | Nogo-a-нейтрализующие иммуноглобулины для лечения неврологических заболеваний |
-
2003
- 2003-09-19 GB GBGB0321997.9A patent/GB0321997D0/en not_active Ceased
-
2004
- 2004-09-16 AR ARP040103334A patent/AR045671A1/es unknown
- 2004-09-17 EP EP04765380A patent/EP1668033A2/en not_active Withdrawn
- 2004-09-17 WO PCT/EP2004/010489 patent/WO2005028508A2/en active Application Filing
- 2004-09-17 CN CNA2004800332675A patent/CN1878792A/zh active Pending
- 2004-09-17 MY MYPI2013003188A patent/MY161068A/en unknown
- 2004-09-17 RU RU2006112849/13A patent/RU2380377C2/ru active
- 2004-09-17 MY MYPI20043786A patent/MY158078A/en unknown
- 2004-09-17 EP EP10176103A patent/EP2423225A3/en not_active Withdrawn
- 2004-09-17 AU AU2004274164A patent/AU2004274164B2/en not_active Ceased
- 2004-09-17 BR BRPI0414174A patent/BRPI0414174B8/pt not_active IP Right Cessation
- 2004-09-17 US US10/572,434 patent/US20090181023A1/en not_active Abandoned
- 2004-09-17 JP JP2006526602A patent/JP2007527232A/ja active Pending
- 2004-09-17 SG SG200806933-8A patent/SG146660A1/en unknown
- 2004-09-17 NZ NZ545679A patent/NZ545679A/en not_active IP Right Cessation
- 2004-09-17 PE PE2004000908A patent/PE20050949A1/es not_active Application Discontinuation
- 2004-09-17 CA CA2538725A patent/CA2538725C/en not_active Expired - Fee Related
- 2004-09-17 TW TW093128254A patent/TWI372060B/zh not_active IP Right Cessation
- 2004-09-17 KR KR1020067005424A patent/KR20060119982A/ko not_active Application Discontinuation
- 2004-09-17 EP EP10160905A patent/EP2248827A1/en not_active Withdrawn
-
2006
- 2006-03-03 ZA ZA200601842A patent/ZA200601842B/en unknown
- 2006-03-06 IL IL174145A patent/IL174145A/en active IP Right Grant
- 2006-03-17 TN TNP2006000085A patent/TNSN06085A1/en unknown
- 2006-03-17 EC EC2006006431A patent/ECSP066431A/es unknown
- 2006-03-29 CO CO06031001A patent/CO5680457A2/es active IP Right Grant
- 2006-04-07 MA MA28921A patent/MA28088A1/fr unknown
- 2006-04-10 IS IS8404A patent/IS8404A/is unknown
- 2006-04-12 NO NO20061678A patent/NO20061678L/no not_active Application Discontinuation
-
2009
- 2009-01-22 AU AU2009200237A patent/AU2009200237B2/en not_active Ceased
- 2009-12-28 IL IL203007A patent/IL203007A/en active IP Right Grant
-
2010
- 2010-06-16 US US12/816,964 patent/US20110008334A1/en not_active Abandoned
Also Published As
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