IN2015KN00449A - - Google Patents

Info

Publication number
IN2015KN00449A
IN2015KN00449A IN449KON2015A IN2015KN00449A IN 2015KN00449 A IN2015KN00449 A IN 2015KN00449A IN 449KON2015 A IN449KON2015 A IN 449KON2015A IN 2015KN00449 A IN2015KN00449 A IN 2015KN00449A
Authority
IN
India
Prior art keywords
patient
debrafenib
trametinib
rfs
time period
Prior art date
Application number
Other languages
English (en)
Inventor
Sylvie Laquerre
Peter F Lebowitz
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50237545&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2015KN00449(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of IN2015KN00449A publication Critical patent/IN2015KN00449A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IN449KON2015 2012-09-04 2013-08-30 IN2015KN00449A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261696375P 2012-09-04 2012-09-04
PCT/US2013/057432 WO2014039375A1 (en) 2012-09-04 2013-08-30 Method of adjuvant cancer treatment

Publications (1)

Publication Number Publication Date
IN2015KN00449A true IN2015KN00449A (ja) 2015-07-17

Family

ID=50237545

Family Applications (1)

Application Number Title Priority Date Filing Date
IN449KON2015 IN2015KN00449A (ja) 2012-09-04 2013-08-30

Country Status (21)

Country Link
US (6) US20150216868A1 (ja)
EP (2) EP2892535B1 (ja)
JP (3) JP2015527374A (ja)
KR (1) KR102134585B1 (ja)
CN (2) CN104582706A (ja)
AU (2) AU2013313050A1 (ja)
BR (1) BR112015004578A2 (ja)
CA (1) CA2882437C (ja)
CY (1) CY1124812T1 (ja)
DK (1) DK2892535T3 (ja)
ES (1) ES2900825T3 (ja)
HK (1) HK1206642A1 (ja)
HR (1) HRP20211817T1 (ja)
HU (1) HUE056646T2 (ja)
IN (1) IN2015KN00449A (ja)
LT (1) LT2892535T (ja)
PL (1) PL2892535T3 (ja)
PT (1) PT2892535T (ja)
RU (1) RU2640180C2 (ja)
SI (1) SI2892535T1 (ja)
WO (1) WO2014039375A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2015KN00449A (ja) 2012-09-04 2015-07-17 Glaxosmithkline Llc
EP3524694B1 (en) 2013-12-28 2020-07-15 Guardant Health, Inc. Methods and systems for detecting genetic variants
FI3618875T3 (fi) * 2017-05-02 2023-07-04 Novartis Ag Raf-inhibiittoria ja trametinibia käsittävä yhdistelmähoito
WO2019204399A1 (en) * 2018-04-17 2019-10-24 The University Of Chicago Methods and compositions for treating cancer
CN109106893B (zh) * 2018-11-12 2021-04-20 上海市中西医结合医院 一种调节肠道屏障功能的中药复方制剂及其制备方法
WO2023105286A1 (en) 2021-12-06 2023-06-15 My Personal Therapeutics Ltd A combination treatment for cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2364596C2 (ru) 2004-06-11 2009-08-20 Джапан Тобакко Инк. ПРОИЗВОДНЫЕ 5-АМИНО-2,4,7-ТРИОКСО-3,4,7,8-ТЕТРАГИДРО-2Н-ПИРИДО[2,3-d] ПИРИМИДИНА, ОБЛАДАЮЩИЕ ПРОТИВООПУХОЛЕВОЙ АКТИВНОСТЬЮ
CN105288630A (zh) * 2005-02-18 2016-02-03 阿布拉科斯生物科学有限公司 治疗剂的组合和给予方式以及联合治疗
UA103319C2 (en) 2008-05-06 2013-10-10 Глаксосмитклайн Ллк Thiazole- and oxazole-benzene sulfonamide compounds
DK3560498T3 (da) * 2009-10-16 2022-11-14 Novartis Ag Kombination, der omfatter en mek-hæmmer og en b-raf-hæmmer
US20130004481A1 (en) * 2011-01-12 2013-01-03 Boehringer Ingelheim International Gmbh Anticancer therapy
IN2015KN00449A (ja) 2012-09-04 2015-07-17 Glaxosmithkline Llc

Also Published As

Publication number Publication date
HK1206642A1 (en) 2016-01-15
RU2640180C2 (ru) 2017-12-26
AU2013313050A1 (en) 2015-03-26
EP3981408A1 (en) 2022-04-13
WO2014039375A1 (en) 2014-03-13
JP2019142899A (ja) 2019-08-29
CA2882437A1 (en) 2014-03-13
PL2892535T3 (pl) 2022-01-31
US20210060021A1 (en) 2021-03-04
US20230330091A1 (en) 2023-10-19
US10869869B2 (en) 2020-12-22
CN104582706A (zh) 2015-04-29
EP2892535A4 (en) 2016-04-13
US20200054641A1 (en) 2020-02-20
KR102134585B1 (ko) 2020-07-17
AU2016244279A1 (en) 2016-11-03
US20150216868A1 (en) 2015-08-06
LT2892535T (lt) 2021-12-10
ES2900825T3 (es) 2022-03-18
CY1124812T1 (el) 2022-11-25
AU2016244279B2 (en) 2018-01-04
HUE056646T2 (hu) 2022-02-28
EP2892535A1 (en) 2015-07-15
CA2882437C (en) 2021-03-02
JP2018058859A (ja) 2018-04-12
EP2892535B1 (en) 2021-09-22
PT2892535T (pt) 2021-12-15
DK2892535T3 (da) 2022-01-03
SI2892535T1 (sl) 2022-01-31
US20170202842A1 (en) 2017-07-20
RU2015105821A (ru) 2016-10-20
JP6511117B2 (ja) 2019-05-15
JP6684941B2 (ja) 2020-04-22
KR20150047619A (ko) 2015-05-04
CN107308164A (zh) 2017-11-03
JP2015527374A (ja) 2015-09-17
US20180338979A1 (en) 2018-11-29
HRP20211817T1 (hr) 2022-03-04
BR112015004578A2 (pt) 2017-07-04

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