IN2015DN03835A - - Google Patents

Download PDF

Info

Publication number
IN2015DN03835A
IN2015DN03835A IN3835DEN2015A IN2015DN03835A IN 2015DN03835 A IN2015DN03835 A IN 2015DN03835A IN 3835DEN2015 A IN3835DEN2015 A IN 3835DEN2015A IN 2015DN03835 A IN2015DN03835 A IN 2015DN03835A
Authority
IN
India
Prior art keywords
liquid
furaldehyde
cmf
monosaccharides
chloromethyl
Prior art date
Application number
Inventor
Aviad Cahana
Edward Nikitin
Jeremy Standiford
Kyle Ellis
Zhang Luzheng
Timothy George
Peter Mikochik
Original Assignee
Xf Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xf Technologies Inc filed Critical Xf Technologies Inc
Publication of IN2015DN03835A publication Critical patent/IN2015DN03835A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C07D307/48—Furfural
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C07D307/48—Furfural
    • C07D307/50—Preparation from natural products

Abstract

The present invention describes methods and apparatuses for the synthesis of 5 (chloromethyl) 2 furaldehyde (CMF) from monosaccharides the method comprising: (a) contacting monosaccharides hydrochloric acid and an organic solvent by way of a continuous biphasic flow reactor assembly at a temperature from about 60 degree C to about 200 degree C and pressures from about 1 atm to 10 atm such that CMF is produced; (b) separating 5 (chloromethyl) 2 furaldehyde by liquid/liquid and solid/liquid phase separation; (c) producing at least five kilograms per day with at least 50% yield.
IN3835DEN2015 2012-10-16 2013-09-03 IN2015DN03835A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261714225P 2012-10-16 2012-10-16
US201361818418P 2013-05-01 2013-05-01
PCT/US2013/057795 WO2014062303A2 (en) 2012-10-16 2013-09-03 Efficient, high-yield conversion of monosaccharides to 5-(chloromethyl)-2-furaldehyde

Publications (1)

Publication Number Publication Date
IN2015DN03835A true IN2015DN03835A (en) 2015-10-02

Family

ID=50488863

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3835DEN2015 IN2015DN03835A (en) 2012-10-16 2013-09-03

Country Status (10)

Country Link
US (1) US9102644B2 (en)
EP (1) EP2909187A4 (en)
CN (1) CN105102440A (en)
BR (1) BR112015008477B1 (en)
CA (1) CA2888298C (en)
IN (1) IN2015DN03835A (en)
MX (1) MX363821B (en)
PH (1) PH12015500818A1 (en)
SG (1) SG11201502939WA (en)
WO (1) WO2014062303A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020039394A1 (en) 2018-08-24 2020-02-27 Novartis Ag New drug combinations
WO2020039386A1 (en) 2018-08-23 2020-02-27 Novartis Ag New pharmaceutical use for the treatment of heart failure

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101924414B1 (en) 2011-06-09 2018-12-03 마이크로마이다스, 인코포레이티드 Utilizing a multiphase reactor for the conversion of biomass to produce substituted furans
US9388151B2 (en) 2012-10-26 2016-07-12 Micromidas, Inc. Methods for producing 5-(halomethyl) furfural
EP2970167A4 (en) 2013-03-14 2016-11-16 Micromidas Inc Solid forms of 5-(halomethyl) furfural and methods for preparing thereof
WO2014159741A1 (en) 2013-03-14 2014-10-02 Micromidas, Inc. Methods for purifying 5-(halomethyl)furfural
TW201527289A (en) 2013-09-20 2015-07-16 Micromidas Inc Methods for producing 5-(halomethyl)furfural
EP3498699A1 (en) 2017-12-13 2019-06-19 Basf Se Chromatography method for the purification of furfural derivatives
JP2021512111A (en) 2018-01-31 2021-05-13 フラニックス・テクノロジーズ・ベーフェー How to convert solid lignocellulosic material
JP2021512102A (en) * 2018-01-31 2021-05-13 フラニックス・テクノロジーズ・ベーフェー Method of conversion of solid lignocellulosic material

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4154744A (en) * 1976-10-12 1979-05-15 Sumitomo Chemical Company, Limited Process for producing a furan derivative
US4335049A (en) * 1980-07-16 1982-06-15 Sumitomo Chemical Company, Limited Process for producing 5-methylfurfural
DE3842825A1 (en) * 1988-01-08 1989-07-20 Krupp Gmbh METHOD AND DEVICE FOR PRODUCING FURFURAL
US7829732B2 (en) * 2008-03-17 2010-11-09 Regents Of The University Of California High-yield conversion of cellulosic biomass into furanic biofuels and value-added products
CA2864086C (en) * 2011-02-28 2018-07-10 Midori Renewables, Inc. Polymeric acid catalysts and uses thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020039386A1 (en) 2018-08-23 2020-02-27 Novartis Ag New pharmaceutical use for the treatment of heart failure
WO2020039394A1 (en) 2018-08-24 2020-02-27 Novartis Ag New drug combinations

Also Published As

Publication number Publication date
EP2909187A4 (en) 2016-05-11
US9102644B2 (en) 2015-08-11
MX2015004716A (en) 2016-08-17
US20140187802A1 (en) 2014-07-03
EP2909187A2 (en) 2015-08-26
BR112015008477A2 (en) 2017-07-04
WO2014062303A3 (en) 2015-07-16
CA2888298A1 (en) 2014-04-24
MX363821B (en) 2019-04-04
PH12015500818A1 (en) 2015-06-08
WO2014062303A2 (en) 2014-04-24
CN105102440A (en) 2015-11-25
CA2888298C (en) 2022-05-31
SG11201502939WA (en) 2015-05-28
BR112015008477B1 (en) 2020-12-08

Similar Documents

Publication Publication Date Title
IN2015DN03835A (en)
MX2012011219A (en) Separation of close boiling compounds by addition of a third compound.
WO2012067980A3 (en) Process for producing 2,3,3,3-tetrafluoropropene and a process for purifying 2-chloro-1,1,1,2-tetrafluoropropane
IN2015DN03742A (en)
MX2012008927A (en) Process for recovering ethanol.
GB201111594D0 (en) New improved process
WO2010085072A3 (en) Divided wall distillation column for producing high purity normal butanol, and normal butanol distillation method
PH12015500644B1 (en) Novel rig-i ligands and methods for producing them
IN2014DN07241A (en)
MX2012013921A (en) Weak acid recovery system for ethanol separation processes.
MY167171A (en) METHOD FOR PRODUCING p-XYLENE AND/OR p-TOLUALDEHYDE
MX2015011051A (en) Process for the preparation of succinic acid ester.
MX346507B (en) Process for producing 2,3,3,3-tetrafluoropropene.
MY183713A (en) Process for the production of dialkyl succinate
IN2015DN01264A (en)
MX2017006073A (en) Process for the production of cyclohexanone from phenol.
WO2012161964A3 (en) Product recovery from adsorption-separation purge fluids
BR112012031086A2 (en) agomelatine intermediates and method of preparation thereof
WO2013028030A3 (en) Method for separating and purifying 1,4-diaminobutane from fermented solution
WO2014102834A3 (en) Process for lurasidone
WO2012053832A3 (en) Method for synthesising 4-o-methylhonokiol
IN2014CN00791A (en)
MY166181A (en) Method for the production of 2-octyl acrylate by means of transesterification
MY164377A (en) Process for production of diacylgylcerol-enriched oil or fat
WO2016105106A3 (en) Continuous production method for anhydrous sugar alcohol