WO2014102834A3 - Process for lurasidone - Google Patents

Process for lurasidone Download PDF

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Publication number
WO2014102834A3
WO2014102834A3 PCT/IN2013/000818 IN2013000818W WO2014102834A3 WO 2014102834 A3 WO2014102834 A3 WO 2014102834A3 IN 2013000818 W IN2013000818 W IN 2013000818W WO 2014102834 A3 WO2014102834 A3 WO 2014102834A3
Authority
WO
WIPO (PCT)
Prior art keywords
lurasidone
substantially free
isomeric impurity
purification
novel process
Prior art date
Application number
PCT/IN2013/000818
Other languages
French (fr)
Other versions
WO2014102834A2 (en
Inventor
Bandi Parthasaradhi Reddy
Kura Rathnakar Reddy
Dasari Muralidhara Reddy
Itiyala Srinivas Reddy
Bandi Vamsi Krishna
Original Assignee
Hetero Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hetero Research Foundation filed Critical Hetero Research Foundation
Publication of WO2014102834A2 publication Critical patent/WO2014102834A2/en
Publication of WO2014102834A3 publication Critical patent/WO2014102834A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

The present invention provides a novel process for the purification of lurasidone substantially free of isomeric impurity. According to on aspect of the present invention, there is provided a novel process for the purification of lurasidone substantially free of isomeric impurity which comprises crystallizing the lurasidone substantially free of isomeric impurity from a solution of lurasidone containing isomeric impurity in an ester solvent or a chlorinated solvent.
PCT/IN2013/000818 2012-12-31 2013-12-30 Process for lurasidone WO2014102834A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN5539/CHE/2012 2012-12-31
IN5539CH2012 2012-12-31

Publications (2)

Publication Number Publication Date
WO2014102834A2 WO2014102834A2 (en) 2014-07-03
WO2014102834A3 true WO2014102834A3 (en) 2015-03-12

Family

ID=51022163

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2013/000818 WO2014102834A2 (en) 2012-12-31 2013-12-30 Process for lurasidone

Country Status (1)

Country Link
WO (1) WO2014102834A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110734434B (en) * 2019-11-19 2022-11-11 湖南洞庭药业股份有限公司 Method for preparing lurasidone and salt thereof
WO2022206447A1 (en) * 2021-03-31 2022-10-06 四川科伦药物研究院有限公司 Injectable lurasidone suspension and preparation method therefor
CN116143771A (en) * 2021-11-19 2023-05-23 北京阳光诺和药物研究股份有限公司 Preparation method of high-purity lurasidone intermediate
CN115073444A (en) * 2022-08-05 2022-09-20 山东科源制药股份有限公司 Method for refining and removing lurasidone hydrochloride epoxy impurities

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532372A (en) * 1990-07-06 1996-07-02 Sumitomo Pharmaceuticals Company, Ltd. Imide derivatives, and their production and use
WO2012107890A2 (en) * 2011-02-10 2012-08-16 Ranbaxy Laboratories Limited Crystalline forms of lurasidone hydrochloride
WO2013121440A1 (en) * 2012-02-13 2013-08-22 Cadila Healthcare Limited Process for preparing benzisothiazol-3-yl-peperazin-l-yl-methyl-cyclo hexyl-methanisoindol-1,3-dione and its intermediates

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532372A (en) * 1990-07-06 1996-07-02 Sumitomo Pharmaceuticals Company, Ltd. Imide derivatives, and their production and use
WO2012107890A2 (en) * 2011-02-10 2012-08-16 Ranbaxy Laboratories Limited Crystalline forms of lurasidone hydrochloride
WO2013121440A1 (en) * 2012-02-13 2013-08-22 Cadila Healthcare Limited Process for preparing benzisothiazol-3-yl-peperazin-l-yl-methyl-cyclo hexyl-methanisoindol-1,3-dione and its intermediates

Also Published As

Publication number Publication date
WO2014102834A2 (en) 2014-07-03

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