IN2015DN02807A - - Google Patents
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- Publication number
- IN2015DN02807A IN2015DN02807A IN2807DEN2015A IN2015DN02807A IN 2015DN02807 A IN2015DN02807 A IN 2015DN02807A IN 2807DEN2015 A IN2807DEN2015 A IN 2807DEN2015A IN 2015DN02807 A IN2015DN02807 A IN 2015DN02807A
- Authority
- IN
- India
- Prior art keywords
- crystalline phase
- absd
- disulfanediylbis
- aminobutane
- lysine
- Prior art date
Links
- HJPXZXVKLGEMGP-YUMQZZPRSA-N (3s)-3-amino-4-[[(2s)-2-amino-4-sulfobutyl]disulfanyl]butane-1-sulfonic acid Chemical compound OS(=O)(=O)CC[C@H](N)CSSC[C@@H](N)CCS(O)(=O)=O HJPXZXVKLGEMGP-YUMQZZPRSA-N 0.000 abstract 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/26—Separation; Purification; Stabilisation; Use of additives
- C07C319/28—Separation; Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention relates to a new crystalline phase of (3S, 3S' ) 4 ,4' disulfanediylbis(3- aminobutane 1 sulfonic acid) (ABSD) with L- lysine and its use , particularly in the pharmaceutical industry, and to processes for preparation thereof. The invention is also directed to pharmaceutical compositions containing at least one crystalline phase of (3S, 3S' ) 4, 4'- disulfanediylbis(3- aminobutane 1 -sulfonic acid) (ABSD) with L -lysine and to the therapeutic or prophylactic use of such crystalline phase and compositions comprising the same.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12306307.5A EP2722327A1 (en) | 2012-10-22 | 2012-10-22 | Crystalline phase of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) with L-lysine |
| PCT/EP2013/072028 WO2014064077A1 (en) | 2012-10-22 | 2013-10-22 | Crystalline phase of (3s.3s') 4,4'-disulfanediylbis(3-aminobutane 1 -sulfonic acid) with l-lysine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2015DN02807A true IN2015DN02807A (en) | 2015-09-11 |
Family
ID=47278723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2807DEN2015 IN2015DN02807A (en) | 2012-10-22 | 2013-10-22 |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US9278921B2 (en) |
| EP (2) | EP2722327A1 (en) |
| JP (1) | JP6317358B2 (en) |
| KR (1) | KR102103407B1 (en) |
| CN (1) | CN104768927B (en) |
| AR (1) | AR093070A1 (en) |
| AU (1) | AU2013336738B2 (en) |
| BR (1) | BR112015008931B1 (en) |
| CA (1) | CA2884914C (en) |
| CY (1) | CY1119913T1 (en) |
| DK (1) | DK2909169T3 (en) |
| EA (1) | EA024460B1 (en) |
| ES (1) | ES2658413T3 (en) |
| HR (1) | HRP20180189T1 (en) |
| HU (1) | HUE036037T2 (en) |
| IL (1) | IL237733B (en) |
| IN (1) | IN2015DN02807A (en) |
| LT (1) | LT2909169T (en) |
| ME (1) | ME02955B (en) |
| MX (1) | MX353693B (en) |
| NO (1) | NO2909169T3 (en) |
| NZ (1) | NZ706070A (en) |
| PL (1) | PL2909169T3 (en) |
| PT (1) | PT2909169T (en) |
| RS (1) | RS56896B1 (en) |
| SI (1) | SI2909169T1 (en) |
| SM (1) | SMT201800086T1 (en) |
| TW (1) | TWI643842B (en) |
| WO (1) | WO2014064077A1 (en) |
| ZA (1) | ZA201503574B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103951562B (en) * | 2014-05-09 | 2016-04-20 | 四川九章生物化工科技发展有限公司 | A kind of chlorogenic acid crystal formation and preparation method thereof |
| WO2022225712A1 (en) * | 2021-04-22 | 2022-10-27 | Teva Pharmaceuticals International Gmbh | Solid state forms of firibastat and processes for preparation thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003271811A1 (en) * | 2002-07-16 | 2004-02-02 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Novel derivatives of 4,4'-dithiobis-(3-aminobutane-1-sulphonates) and compositions containing same |
| FR2858617A1 (en) * | 2003-08-06 | 2005-02-11 | Inst Nat Sante Rech Med | NOVEL 4 ', 4'-DITHIOBIS- (3-AMINOBUTANE-1-SULFONATE-1-SULFONATES) DERIVATIVES AND COMPOSITIONS CONTAINING SAME |
| TWI370818B (en) * | 2006-04-05 | 2012-08-21 | Astellas Pharma Inc | Cocrystal of c-glycoside derivative and l-proline |
| EP2439192A1 (en) | 2010-10-07 | 2012-04-11 | Quantum Genomics | Method for the preparation of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) |
| WO2012138907A2 (en) * | 2011-04-05 | 2012-10-11 | Translational Genomics Research Institute | Solid forms of curcumin |
-
2012
- 2012-10-22 EP EP12306307.5A patent/EP2722327A1/en not_active Withdrawn
-
2013
- 2013-10-18 AR ARP130103795A patent/AR093070A1/en unknown
- 2013-10-22 JP JP2015537299A patent/JP6317358B2/en not_active Expired - Fee Related
- 2013-10-22 KR KR1020157013661A patent/KR102103407B1/en active Active
- 2013-10-22 SI SI201330952T patent/SI2909169T1/en unknown
- 2013-10-22 AU AU2013336738A patent/AU2013336738B2/en not_active Ceased
- 2013-10-22 CA CA2884914A patent/CA2884914C/en active Active
- 2013-10-22 ES ES13779603.3T patent/ES2658413T3/en active Active
- 2013-10-22 NZ NZ706070A patent/NZ706070A/en not_active IP Right Cessation
- 2013-10-22 WO PCT/EP2013/072028 patent/WO2014064077A1/en not_active Application Discontinuation
- 2013-10-22 DK DK13779603.3T patent/DK2909169T3/en active
- 2013-10-22 BR BR112015008931-3A patent/BR112015008931B1/en not_active IP Right Cessation
- 2013-10-22 HU HUE13779603A patent/HUE036037T2/en unknown
- 2013-10-22 LT LTEP13779603.3T patent/LT2909169T/en unknown
- 2013-10-22 ME MEP-2018-29A patent/ME02955B/en unknown
- 2013-10-22 SM SM20180086T patent/SMT201800086T1/en unknown
- 2013-10-22 MX MX2015005059A patent/MX353693B/en active IP Right Grant
- 2013-10-22 PT PT137796033T patent/PT2909169T/en unknown
- 2013-10-22 US US14/437,343 patent/US9278921B2/en not_active Expired - Fee Related
- 2013-10-22 CN CN201380052793.5A patent/CN104768927B/en not_active Expired - Fee Related
- 2013-10-22 PL PL13779603T patent/PL2909169T3/en unknown
- 2013-10-22 TW TW102138122A patent/TWI643842B/en not_active IP Right Cessation
- 2013-10-22 IN IN2807DEN2015 patent/IN2015DN02807A/en unknown
- 2013-10-22 RS RS20180133A patent/RS56896B1/en unknown
- 2013-10-22 HR HRP20180189TT patent/HRP20180189T1/en unknown
- 2013-10-22 EA EA201500438A patent/EA024460B1/en unknown
- 2013-10-22 NO NO13779603A patent/NO2909169T3/no unknown
- 2013-10-22 EP EP13779603.3A patent/EP2909169B1/en active Active
-
2015
- 2015-03-12 IL IL237733A patent/IL237733B/en active IP Right Grant
- 2015-05-21 ZA ZA2015/03574A patent/ZA201503574B/en unknown
-
2016
- 2016-02-01 US US15/012,625 patent/US9487477B2/en not_active Expired - Fee Related
-
2018
- 2018-02-14 CY CY20181100179T patent/CY1119913T1/en unknown
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