IN2015DN00928A - - Google Patents
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- Publication number
- IN2015DN00928A IN2015DN00928A IN928DEN2015A IN2015DN00928A IN 2015DN00928 A IN2015DN00928 A IN 2015DN00928A IN 928DEN2015 A IN928DEN2015 A IN 928DEN2015A IN 2015DN00928 A IN2015DN00928 A IN 2015DN00928A
- Authority
- IN
- India
- Prior art keywords
- tiacumicin
- antifoaming
- fermentation
- micro
- procedure
- Prior art date
Links
- ZVGNESXIJDCBKN-UUEYKCAUSA-N fidaxomicin Chemical compound O([C@@H]1[C@@H](C)O[C@H]([C@H]([C@H]1O)OC)OCC\1=C/C=C/C[C@H](O)/C(C)=C/[C@@H]([C@H](/C(C)=C/C(/C)=C/C[C@H](OC/1=O)[C@@H](C)O)O[C@H]1[C@H]([C@@H](O)[C@H](OC(=O)C(C)C)C(C)(C)O1)O)CC)C(=O)C1=C(O)C(Cl)=C(O)C(Cl)=C1CC ZVGNESXIJDCBKN-UUEYKCAUSA-N 0.000 abstract 2
- 229960000628 fidaxomicin Drugs 0.000 abstract 2
- 241000183229 Actinoplanes deccanensis Species 0.000 abstract 1
- 241001495431 Dactylosporangium aurantiacum Species 0.000 abstract 1
- 230000003254 anti-foaming effect Effects 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 239000008158 vegetable oil Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/58—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound through only acyclic carbon atoms to a non-saccharide heterocyclic ring, e.g. bleomycin, phleomycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001406A ITMI20121406A1 (it) | 2012-08-07 | 2012-08-07 | Procedimento per la produzione di tiacumicina b |
| IT000856A ITMI20130856A1 (it) | 2013-05-27 | 2013-05-27 | Procedimento per la produzione di tiacumicina b |
| PCT/EP2013/065994 WO2014023616A1 (en) | 2012-08-07 | 2013-07-30 | Procedure for the production of tiacumicin b |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2015DN00928A true IN2015DN00928A (cs) | 2015-06-12 |
Family
ID=49000913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN928DEN2015 IN2015DN00928A (cs) | 2012-08-07 | 2013-07-30 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9970041B2 (cs) |
| EP (1) | EP2882860B1 (cs) |
| CN (1) | CN104603279A (cs) |
| CA (1) | CA2881302C (cs) |
| DK (1) | DK2882860T3 (cs) |
| HK (1) | HK1210225A1 (cs) |
| IN (1) | IN2015DN00928A (cs) |
| WO (1) | WO2014023616A1 (cs) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104946708B (zh) * | 2014-03-28 | 2018-06-12 | 上海医药工业研究院 | 一种生产非达霉素的发酵培养基以及发酵方法 |
| CN104098637B (zh) | 2014-07-09 | 2017-01-04 | 浙江海正药业股份有限公司 | 一种纯化非达霉素的方法 |
| CN108841769B (zh) * | 2018-05-24 | 2021-03-02 | 浙江大学 | 一种非达霉素基因工程菌及构建方法和应用 |
| CN112430555B (zh) * | 2020-12-11 | 2022-06-24 | 浙江大学 | 一种放线菌底盘菌株及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1458512A (en) * | 1973-11-22 | 1976-12-15 | Lepetit Spa | Antibiotic substance |
| US4918174A (en) | 1986-09-26 | 1990-04-17 | Abbott Laboratories | Tiacumicin compounds |
| CN100519757C (zh) * | 2002-07-29 | 2009-07-29 | 浩鼎生技公司 | 台勾霉素的制备 |
-
2013
- 2013-07-30 IN IN928DEN2015 patent/IN2015DN00928A/en unknown
- 2013-07-30 WO PCT/EP2013/065994 patent/WO2014023616A1/en active Application Filing
- 2013-07-30 CN CN201380041582.1A patent/CN104603279A/zh active Pending
- 2013-07-30 HK HK15110889.6A patent/HK1210225A1/xx unknown
- 2013-07-30 DK DK13750659.8T patent/DK2882860T3/en active
- 2013-07-30 US US14/419,955 patent/US9970041B2/en active Active
- 2013-07-30 EP EP13750659.8A patent/EP2882860B1/en active Active
- 2013-07-30 CA CA2881302A patent/CA2881302C/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2881302A1 (en) | 2014-02-13 |
| EP2882860A1 (en) | 2015-06-17 |
| CA2881302C (en) | 2020-12-15 |
| HK1210225A1 (en) | 2016-04-15 |
| US9970041B2 (en) | 2018-05-15 |
| DK2882860T3 (en) | 2016-08-22 |
| WO2014023616A1 (en) | 2014-02-13 |
| US20150203889A1 (en) | 2015-07-23 |
| CN104603279A (zh) | 2015-05-06 |
| EP2882860B1 (en) | 2016-05-04 |
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