IN2014MU00212A - - Google Patents

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Publication number
IN2014MU00212A
IN2014MU00212A IN212MU2014A IN2014MU00212A IN 2014MU00212 A IN2014MU00212 A IN 2014MU00212A IN 212MU2014 A IN212MU2014 A IN 212MU2014A IN 2014MU00212 A IN2014MU00212 A IN 2014MU00212A
Authority
IN
India
Prior art keywords
free base
amorphous form
sitagliptin free
sitagliptin
provides
Prior art date
Application number
Other languages
English (en)
Inventor
Shri Prakash Dhar Dwivedi
Brij Khera
Kumar Kamlesh Singh
Kirtipalsinh Sajjansinh Solanki
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Priority to IN212MU2014 priority Critical patent/IN2014MU00212A/en
Priority to PCT/IN2015/000035 priority patent/WO2015114657A2/en
Publication of IN2014MU00212A publication Critical patent/IN2014MU00212A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN212MU2014 2014-01-21 2015-01-21 IN2014MU00212A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IN212MU2014 IN2014MU00212A (zh) 2014-01-21 2015-01-21
PCT/IN2015/000035 WO2015114657A2 (en) 2014-01-21 2015-01-21 Amorphous form of sitagliptin free base

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN212MU2014 IN2014MU00212A (zh) 2014-01-21 2015-01-21

Publications (1)

Publication Number Publication Date
IN2014MU00212A true IN2014MU00212A (zh) 2015-08-28

Family

ID=53059374

Family Applications (1)

Application Number Title Priority Date Filing Date
IN212MU2014 IN2014MU00212A (zh) 2014-01-21 2015-01-21

Country Status (2)

Country Link
IN (1) IN2014MU00212A (zh)
WO (1) WO2015114657A2 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2016016260A (es) 2016-12-08 2018-06-07 Alparis Sa De Cv Nuevas formas solidas de sitagliptina.
CN109580833B (zh) * 2018-12-31 2021-12-03 辰欣药业股份有限公司 一种西格列汀原料及制剂中对映异构体杂质的测定方法
KR20210057603A (ko) 2019-11-12 2021-05-21 제이투에이치바이오텍 (주) 시타글립틴의 제조방법

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA74912C2 (en) 2001-07-06 2006-02-15 Merck & Co Inc Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
WO2004085661A2 (en) * 2003-03-24 2004-10-07 Merck & Co., Inc Process to chiral beta-amino acid derivatives
JO2625B1 (en) 2003-06-24 2011-11-01 ميرك شارب اند دوم كوربوريشن Phosphoric acid salts of dipeptidyl betidase inhibitor 4
CN100457108C (zh) 2003-09-02 2009-02-04 默克公司 一种二肽基肽酶iv抑制剂的磷酸盐新晶体
WO2005030127A2 (en) 2003-09-23 2005-04-07 Merck & Co., Inc. Novel crystalline form of a phosphoric acid salt of a dipeptidyl peptidase-iv inhibitor
US20090221592A1 (en) 2005-07-25 2009-09-03 Ellison Martha E Dodecylsulfate Salt Of A Dipeptidyl Peptidase-Iv Inhibitor
WO2009084024A2 (en) 2007-11-02 2009-07-09 Glenmark Generics Limited A process for the preparation of r-sit agliptin and its pharmaceutically acceptable salts thereof
US20090221595A1 (en) * 2007-11-26 2009-09-03 Nurit Perlman Crystalline form of sitagliptin
TW201000485A (en) 2008-03-25 2010-01-01 Teva Pharma Crystalline forms of sitagliptin phosphate
EP2650299A1 (en) 2008-07-03 2013-10-16 Ratiopharm GmbH Crystalline salts of sitagliptin
WO2010122578A2 (en) 2009-04-20 2010-10-28 Msn Laboratories Limited Process for the preparation of sitagliptin and its intermediates
US8846916B2 (en) * 2009-05-11 2014-09-30 Generics [Uk] Limited Sitagliptin synthesis
EA022485B1 (ru) 2009-08-13 2016-01-29 Сандоз Аг КРИСТАЛЛИЧЕСКОЕ СОЕДИНЕНИЕ 7-[(3R)-3-АМИНО-1-ОКСО-4-(2,4,5-ТРИФТОРФЕНИЛ)БУТИЛ]-5,6,7,8-ТЕТРАГИДРО-3-(ТРИФТОРМЕТИЛ)-1,2,4-ТРИАЗОЛО[4,3-a]ПИРАЗИНА
KR101222679B1 (ko) * 2009-10-21 2013-01-16 한미사이언스 주식회사 시타글립틴의 제조 방법 및 이에 사용되는 중간체
EP2407469A1 (en) 2010-07-13 2012-01-18 Chemo Ibérica, S.A. Salt of sitagliptin
WO2012076973A2 (en) 2010-12-09 2012-06-14 Aurobindo Pharma Limited Novel salts of dipeptidyl peptidase iv inhibitor
SI2691083T1 (sl) * 2011-03-29 2017-12-29 Krka, D.D., Novo Mesto Farmacevtski sestavek sitagliptina
WO2013001514A1 (en) 2011-06-29 2013-01-03 Ranbaxy Laboratories Limited Solid dispersions of sitagliptin and processes for their preparation

Also Published As

Publication number Publication date
WO2015114657A3 (en) 2015-10-08
WO2015114657A2 (en) 2015-08-06

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