IN2014MN02147A - - Google Patents

Download PDF

Info

Publication number
IN2014MN02147A
IN2014MN02147A IN2147MUN2014A IN2014MN02147A IN 2014MN02147 A IN2014MN02147 A IN 2014MN02147A IN 2147MUN2014 A IN2147MUN2014 A IN 2147MUN2014A IN 2014MN02147 A IN2014MN02147 A IN 2014MN02147A
Authority
IN
India
Prior art keywords
sample matrix
probe
concentration
reflective surface
measuring
Prior art date
Application number
Other languages
English (en)
Inventor
Hannu Harjunmaa
Stevan Kun
Original Assignee
Grove Instr Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grove Instr Inc filed Critical Grove Instr Inc
Publication of IN2014MN02147A publication Critical patent/IN2014MN02147A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/49Scattering, i.e. diffuse reflection within a body or fluid
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04Constructional details of apparatus
    • A61B2560/0431Portable apparatus, e.g. comprising a handle or case
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233Special features of optical sensors or probes classified in A61B5/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/14Coupling media or elements to improve sensor contact with skin or tissue
    • A61B2562/146Coupling media or elements to improve sensor contact with skin or tissue for optical coupling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0048Detecting, measuring or recording by applying mechanical forces or stimuli
    • A61B5/0051Detecting, measuring or recording by applying mechanical forces or stimuli by applying vibrations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6814Head
    • A61B5/6815Ear
    • A61B5/6816Ear lobe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6825Hand
    • A61B5/6826Finger
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04CROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00Control; Monitoring or safety arrangements
    • F04C2270/04Force
    • F04C2270/041Controlled or regulated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N2021/3148Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths using three or more wavelengths
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N2021/4704Angular selective
    • G01N2021/4709Backscatter
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/4738Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G01N21/474Details of optical heads therefor, e.g. using optical fibres
    • G01N2021/4742Details of optical heads therefor, e.g. using optical fibres comprising optical fibres
    • G01N2021/475Bifurcated bundle
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/4738Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G01N21/474Details of optical heads therefor, e.g. using optical fibres
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/02Mechanical
    • G01N2201/022Casings
    • G01N2201/0221Portable; cableless; compact; hand-held
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/063Illuminating optical parts
    • G01N2201/0631Homogeneising elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/063Illuminating optical parts
    • G01N2201/0636Reflectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ecology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
IN2147MUN2014 2012-04-06 2013-04-04 IN2014MN02147A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/441,467 US20130267799A1 (en) 2012-04-06 2012-04-06 Noninvasive measurement of analyte concentration using a fiberless transflectance probe
PCT/US2013/035250 WO2013152177A1 (en) 2012-04-06 2013-04-04 Noninvasive measurement of analyte concentration using a fiberless transflectance probe

Publications (1)

Publication Number Publication Date
IN2014MN02147A true IN2014MN02147A (ja) 2015-08-21

Family

ID=48227538

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2147MUN2014 IN2014MN02147A (ja) 2012-04-06 2013-04-04

Country Status (11)

Country Link
US (1) US20130267799A1 (ja)
EP (1) EP2834620A1 (ja)
JP (1) JP6444857B2 (ja)
KR (1) KR20150050523A (ja)
CN (1) CN104395732A (ja)
AU (1) AU2013243441A1 (ja)
CA (1) CA2869607A1 (ja)
HK (1) HK1201325A1 (ja)
IL (1) IL234976A0 (ja)
IN (1) IN2014MN02147A (ja)
WO (1) WO2013152177A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105249974A (zh) * 2015-10-15 2016-01-20 华南师范大学 一种基于压力调制光谱技术的无创葡萄糖检测系统与方法
GB201812766D0 (en) * 2018-08-06 2018-09-19 Res & Innovation Uk Optical multi-pass cells
US20210093252A1 (en) * 2019-10-01 2021-04-01 Avid Najdahmadi Light-based medical device
WO2021233561A1 (en) * 2020-05-20 2021-11-25 Diamontech Ag Method and apparatus for analyzing a material with asymmetric or harmonic intensity modulation of excitation radiation
WO2021233560A1 (en) * 2020-05-20 2021-11-25 Diamontech Ag Method and apparatus for analyte measurement including real-time quality assessment and improvement

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3986777A (en) * 1974-08-22 1976-10-19 Weber Dental Mfg. Co., Div. Of Sterndent Corporation Tristimulus colorimeter for use in the fabrication of artificial teeth
US5178142A (en) 1989-05-23 1993-01-12 Vivascan Corporation Electromagnetic method and apparatus to measure constituents of human or animal tissue
US5183042A (en) 1989-05-23 1993-02-02 Vivascan Corporation Electromagnetic method and apparatus to measure constituents of human or animal tissue
US5137023A (en) 1990-04-19 1992-08-11 Worcester Polytechnic Institute Method and apparatus for monitoring blood analytes noninvasively by pulsatile photoplethysmography
EP0401453B1 (en) 1989-05-23 1992-09-02 Biosensors Technology, Inc. Method for determining by absorption of radiations the concentration of substances in absorbing and turbid matrices
US5112124A (en) 1990-04-19 1992-05-12 Worcester Polytechnic Institute Method and apparatus for measuring the concentration of absorbing substances
ATE157230T1 (de) * 1991-07-03 1997-09-15 Vivascan Corp Verfahren und vorrichtung zur elektromagnetischen bestimmung von im lebenden gewebe vorliegenden substanzen
US5277181A (en) 1991-12-12 1994-01-11 Vivascan Corporation Noninvasive measurement of hematocrit and hemoglobin content by differential optical analysis
WO1993012712A1 (en) 1991-12-31 1993-07-08 Vivascan Corporation Blood constituent determination based on differential spectral analysis
US5851178A (en) * 1995-06-02 1998-12-22 Ohmeda Inc. Instrumented laser diode probe connector
US6174424B1 (en) * 1995-11-20 2001-01-16 Cirrex Corp. Couplers for optical fibers
US5830137A (en) * 1996-11-18 1998-11-03 University Of South Florida Green light pulse oximeter
US6070093A (en) * 1997-12-02 2000-05-30 Abbott Laboratories Multiplex sensor and method of use
US8175666B2 (en) * 2002-04-26 2012-05-08 Grove Instruments, Inc. Three diode optical bridge system
US7003337B2 (en) * 2002-04-26 2006-02-21 Vivascan Corporation Non-invasive substance concentration measurement using and optical bridge
JP2004081427A (ja) * 2002-08-26 2004-03-18 Kenji Yoshikawa 生体内水分測定装置
JP2004290545A (ja) * 2003-03-28 2004-10-21 Citizen Watch Co Ltd 血液分析装置
EP1931257A4 (en) * 2005-09-06 2009-08-26 Nir Diagnostics Inc METHOD AND DEVICE FOR MEASURING ANALYTES

Also Published As

Publication number Publication date
IL234976A0 (en) 2014-12-31
AU2013243441A1 (en) 2014-10-30
WO2013152177A1 (en) 2013-10-10
JP2015512326A (ja) 2015-04-27
EP2834620A1 (en) 2015-02-11
US20130267799A1 (en) 2013-10-10
CN104395732A (zh) 2015-03-04
CA2869607A1 (en) 2013-10-10
WO2013152177A8 (en) 2013-12-05
HK1201325A1 (en) 2015-08-28
KR20150050523A (ko) 2015-05-08
JP6444857B2 (ja) 2018-12-26

Similar Documents

Publication Publication Date Title
IN2014MN02147A (ja)
MX344918B (es) Sistema de análisis bioluminiscente y de recolección de muestras.
WO2007090147A3 (en) Method and apparatus for measurement of optical properties in tissue
MX361943B (es) Eficiente formación modulada de imágenes.
WO2008039299A3 (en) Three diode optical bridge system
BR112015022216A2 (pt) método e dispositivo para correção de sinais ópticos
WO2007089540A3 (en) Handheld raman body fluid analyzer
Feder et al. Experimentally testing the role of blood vessels in the full scattering profile: solid phantom measurements
EP1894520A3 (en) Body fat measurement apparatus and method of operating the apparatus
WO2009120600A3 (en) Method and system for non-invasive blood glucose detection utilizing spectral data of one or more components other than glucose
RU2011150502A (ru) Устройство анализа стенки кровеносного сосуда и способ анализа стенки кровеносного сосуда
Darvin et al. Multiple spatially resolved reflection spectroscopy for in vivo determination of carotenoids in human skin and blood
CN108489962B (zh) 一种基于空间偏移拉曼光谱技术的生物组织检测装置
EP3276338A3 (en) X-ray fluorescence analyzer
Yang et al. Reference point of floating-reference method for blood glucose sensing
IN2014CN03410A (ja)
Srivastava et al. Measurement of glucose concentration using amplitude modulated ultrasound with infrared technique in intralipid phantoms and human whole blood mixed intralipid phantom of healthy and diabetic subjects
Gao et al. A CT-analogous scheme for time-domain diffuse fluorescence tomography
WO2012063229A2 (en) Reflectance meausrement device and method for localizing vein and artery
Braun et al. NADH-fluorescence scattering correction for absolute concentration determination in a liquid tissue phantom using a novel multispectral magnetic-resonance-imaging-compatible needle probe
CN104880468B (zh) 一种毫米波探头源探距离确定方法及系统
JP2015040744A (ja) 光学的測定方法
Morsin et al. Development of plasmonic sensor for detection of toxic materials
Canpolat Variation of photon density distribution with system component within Intralipid emulsion
Yao et al. Measurement of Grüneisen parameter of tissue by photoacoustic spectrometry