IN2014MN01795A - - Google Patents
Download PDFInfo
- Publication number
- IN2014MN01795A IN2014MN01795A IN1795MUN2014A IN2014MN01795A IN 2014MN01795 A IN2014MN01795 A IN 2014MN01795A IN 1795MUN2014 A IN1795MUN2014 A IN 1795MUN2014A IN 2014MN01795 A IN2014MN01795 A IN 2014MN01795A
- Authority
- IN
- India
- Prior art keywords
- patient
- biological fluid
- percentage
- bcl2l10 protein
- sample
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/82—Translation products from oncogenes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/54—Determining the risk of relapse
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Abstract
The invention relates to an analysis method for predicting resistance to azacitidine treatment in a patient using the BCL2L10 protein contained in a sample of biological fluid taken from said patient and also biological molecules which specifically bind the BCL2L10 protein. It is characterized in that a sample of biological fluid is recovered from a patient; the percentage of total cells in said biological fluid expressing the BCL2L10 protein is calculated; this calculated percentage is compared with a reference threshold value this threshold value being between 20% and 60%; and resistance to azacitidine treatment is diagnosed in a patient who has a percentage of cells expressing the BCL2L10 protein in said biological fluid which is greater than said reference value.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1200584A FR2987446B1 (en) | 2012-02-28 | 2012-02-28 | DIAGNOSTIC TEST FOR RESISTANCE TO AZACITIDINE |
PCT/FR2013/000055 WO2013128089A1 (en) | 2012-02-28 | 2013-02-28 | Test for diagnosing resistance to azacitidine |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014MN01795A true IN2014MN01795A (en) | 2015-07-03 |
Family
ID=48083449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1795MUN2014 IN2014MN01795A (en) | 2012-02-28 | 2013-02-28 |
Country Status (11)
Country | Link |
---|---|
US (1) | US20150094217A1 (en) |
EP (1) | EP2820417A1 (en) |
JP (1) | JP6273552B2 (en) |
CN (1) | CN104321649A (en) |
AU (1) | AU2013224832A1 (en) |
BR (1) | BR112014021173A2 (en) |
CA (1) | CA2865684A1 (en) |
FR (1) | FR2987446B1 (en) |
IL (1) | IL234332A0 (en) |
IN (1) | IN2014MN01795A (en) |
WO (1) | WO2013128089A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3042650B1 (en) * | 2014-03-27 | 2020-06-10 | Palacky University, Olomouc | Bromodomain inhibitor jq1 in combination with dna methylation inhibitor dac for use in cancer treatment |
FR3048698B1 (en) * | 2016-03-11 | 2021-03-05 | Univ Claude Bernard Lyon | BCL2 L10 INTERACTION INHIBITORS / IP3 RECEIVER |
WO2019077080A1 (en) * | 2017-10-19 | 2019-04-25 | Universite Claude Bernard Lyon 1 | Evaluation of the risk of metastatic relapse in breast cancer patients |
CN114874987A (en) * | 2022-03-01 | 2022-08-09 | 洛阳市中心医院(郑州大学附属洛阳中心医院) | Myelodysplastic syndrome drug-resistant cell model and construction method and application thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005078100A1 (en) * | 2004-02-13 | 2005-08-25 | Bml, Inc. | Method of detecting cancer cell acquiring drug-resistance |
ES2550614T3 (en) * | 2004-04-09 | 2015-11-11 | Genomic Health, Inc. | Gene expression markers to predict the response to chemotherapy |
WO2010045651A1 (en) * | 2008-10-17 | 2010-04-22 | Nodality, Inc. | Methods for analyzing drug response |
CN101632643A (en) * | 2009-08-18 | 2010-01-27 | 杭州咸达医药科技有限公司 | Azacitidine freeze-drying powder injection and preparation method thereof |
JP5190477B2 (en) * | 2010-02-22 | 2013-04-24 | 譲治 稲澤 | Method for detecting lung cancer cells that have acquired drug resistance to camptothecins against anticancer drugs |
ES2656962T3 (en) * | 2010-05-27 | 2018-03-01 | Inserm - Institut National De La Santé Et De La Recherche Médicale | Methods to assess the receptivity of a patient's endometrium |
-
2012
- 2012-02-28 FR FR1200584A patent/FR2987446B1/en not_active Expired - Fee Related
-
2013
- 2013-02-28 IN IN1795MUN2014 patent/IN2014MN01795A/en unknown
- 2013-02-28 JP JP2014559271A patent/JP6273552B2/en not_active Expired - Fee Related
- 2013-02-28 US US14/381,406 patent/US20150094217A1/en not_active Abandoned
- 2013-02-28 AU AU2013224832A patent/AU2013224832A1/en not_active Abandoned
- 2013-02-28 CA CA2865684A patent/CA2865684A1/en not_active Abandoned
- 2013-02-28 WO PCT/FR2013/000055 patent/WO2013128089A1/en active Application Filing
- 2013-02-28 CN CN201380013105.4A patent/CN104321649A/en active Pending
- 2013-02-28 BR BR112014021173A patent/BR112014021173A2/en not_active IP Right Cessation
- 2013-02-28 EP EP13715265.8A patent/EP2820417A1/en not_active Withdrawn
-
2014
- 2014-08-27 IL IL234332A patent/IL234332A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP6273552B2 (en) | 2018-02-07 |
FR2987446B1 (en) | 2016-01-01 |
IL234332A0 (en) | 2014-10-30 |
FR2987446A1 (en) | 2013-08-30 |
CA2865684A1 (en) | 2013-09-06 |
WO2013128089A1 (en) | 2013-09-06 |
US20150094217A1 (en) | 2015-04-02 |
AU2013224832A1 (en) | 2014-10-16 |
AU2013224832A8 (en) | 2014-11-13 |
CN104321649A (en) | 2015-01-28 |
BR112014021173A2 (en) | 2017-08-22 |
JP2015513369A (en) | 2015-05-11 |
EP2820417A1 (en) | 2015-01-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA201903597B (en) | Biosensors for biological or chemical analysis and methods of manufacturing the same | |
CY1120434T1 (en) | IL-1 ACCUMULATION PROTEINS | |
WO2013190075A3 (en) | Specific biomarkers for hepatocellular carcinoma (hcc) | |
EA201590247A1 (en) | ANTIBODIES TO SIGLEC-15 | |
SG10201903822XA (en) | Method for the enrichment of circulating tumor dna | |
EP3076949A4 (en) | Analysis of genomic dna, rna, and proteins in exosomes for diagnosis and theranosis | |
PL2986735T3 (en) | Method for identifying the quantitative composition of blood cells in a sample | |
MX2016011377A (en) | Method for diagnosing colorectal cancer from a human feces sample by quantitive pcr, primers and kit. | |
WO2012094580A3 (en) | Compounds that modulate oxidative stress | |
WO2012122564A3 (en) | Diagnostic and sample preparation devices and methods | |
EP2813854A4 (en) | Hemolysis reagent composition for hemoglobin a1c quantitative analysis using enzymatic method | |
MX357429B (en) | Predictors for cancer treatment. | |
EP3287791A4 (en) | Method for evaluating coagulation ability of blood specimen, and reagent, reagent kit and device to be used therein | |
IN2014MN01795A (en) | ||
EP2569635A4 (en) | Methods for diagnosing and treating encephalitis or epilepsy | |
EP2909589A4 (en) | Ultrasonic biological sample analysis apparatus and methods | |
SG11201700876RA (en) | Methods and compositions for analyzing glucose-6-phosphate dehydrogenase activity in blood samples | |
WO2014053996A3 (en) | Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs | |
MX2021009528A (en) | Rgma fragment based diagnostic assay. | |
HUE043360T2 (en) | Container for determining of analytes and/or chemico-physical parameters, as well as determining of urinary sediment, in urine; and method of full urine analysis using this container | |
HK1183064A1 (en) | Sandwich immuno-pcr detection method and kit of analyte in biological samples pcr | |
EP2732288A4 (en) | Biological microchip for the estimation of immunoglobulin e and g levels in human blood, method of assay thereof, and reagent kit comprising same | |
ZA201402460B (en) | Assembly for determining the presence or absence of an analyte in a blood sample and analysis unit comprising such an assembly | |
MX2015011804A (en) | Methods and compositions for diagnosing preeclampsia. | |
WO2013077814A3 (en) | Natural-killer/t-cell lymphoma (nktcl) susceptibility prediction, diagnosis and therapy |