IN2014MN01554A - - Google Patents

Info

Publication number
IN2014MN01554A
IN2014MN01554A IN1554MUN2014A IN2014MN01554A IN 2014MN01554 A IN2014MN01554 A IN 2014MN01554A IN 1554MUN2014 A IN1554MUN2014 A IN 1554MUN2014A IN 2014MN01554 A IN2014MN01554 A IN 2014MN01554A
Authority
IN
India
Prior art keywords
geranylgeranylacetone
phosphoric acid
composition containing
buffering agent
acid buffering
Prior art date
Application number
Inventor
MIYANOTakayuki
KUROSETakahiro
Original Assignee
Rohto Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohto Pharma filed Critical Rohto Pharma
Publication of IN2014MN01554A publication Critical patent/IN2014MN01554A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

An ophthalmic composition containing a geranylgeranylacetone and a phosphoric acid buffering agent has an extremely small decline in the content of the geranylgeranylacetone when the composition is stored for a long period of time because the adsorption of the geranylgeranylacetone into an ophthalmic container wall is inhibited. Moreover the geranylgeranylacetone in the ophthalmic composition containing the geranylgeranylacetone and the phosphoric acid buffering agent is hardly adsorbed into a contact lens. Additionally the ophthalmic composition containing the geranylgeranylacetone and the phosphoric acid buffering agent is less likely to become cloudy when being stored at low temperatures.
IN1554MUN2014 2012-02-27 2013-02-25 IN2014MN01554A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012040729 2012-02-27
PCT/JP2013/054782 WO2013129319A1 (en) 2012-02-27 2013-02-25 Ophthalmic composition

Publications (1)

Publication Number Publication Date
IN2014MN01554A true IN2014MN01554A (en) 2015-05-22

Family

ID=49082516

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1554MUN2014 IN2014MN01554A (en) 2012-02-27 2013-02-25

Country Status (7)

Country Link
US (2) US20130303626A1 (en)
JP (2) JP5345745B1 (en)
CN (1) CN104136017A (en)
HK (1) HK1200113A1 (en)
IN (1) IN2014MN01554A (en)
TW (1) TW201340962A (en)
WO (1) WO2013129319A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5483513B1 (en) * 2013-02-19 2014-05-07 ロート製薬株式会社 Mucosal application agent for prevention, improvement, or treatment of retinal diseases
WO2014129466A1 (en) * 2013-02-19 2014-08-28 ロート製薬株式会社 Mucosal application agent for preventing, ameliorating or treating retinal disease
TW201542196A (en) * 2013-08-26 2015-11-16 Rohto Pharma Ophthalmic formulation
JPWO2015029924A1 (en) * 2013-08-26 2017-03-02 ロート製薬株式会社 Ophthalmic composition
WO2015029926A1 (en) * 2013-08-26 2015-03-05 ロート製薬株式会社 Ophthalmological composition
US20170105934A1 (en) * 2014-06-10 2017-04-20 Rohto Pharmaceutical Co., Ltd. Aqueous ophthalmic composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0418015A (en) * 1990-05-10 1992-01-22 Fujikawa Kk Stable aqueous solution of clemastine fumarate
JPH08133967A (en) * 1994-11-02 1996-05-28 Eisai Co Ltd Agent for treating dry eye
JP2000319170A (en) * 1999-03-05 2000-11-21 Eisai Co Ltd Teprenone-containing eye lotion
JP2000258735A (en) * 1999-03-10 2000-09-22 Kuraray Co Ltd Liquid for contact lens
JP2005298452A (en) * 2004-04-16 2005-10-27 Saga Seiyaku Kk Method for stabilizing azulene derivative-containing aqueous liquid preparation
US20090239775A1 (en) * 2008-03-19 2009-09-24 Collins Gary L Ophthalmic solutions displaying improved efficacy

Also Published As

Publication number Publication date
WO2013129319A1 (en) 2013-09-06
US20130303626A1 (en) 2013-11-14
TW201340962A (en) 2013-10-16
JP2013213051A (en) 2013-10-17
JP5345745B1 (en) 2013-11-20
CN104136017A (en) 2014-11-05
HK1200113A1 (en) 2015-07-31
US20160136275A1 (en) 2016-05-19
JPWO2013129319A1 (en) 2015-07-30

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