IN2014MN01553A - - Google Patents

Info

Publication number
IN2014MN01553A
IN2014MN01553A IN1553MUN2014A IN2014MN01553A IN 2014MN01553 A IN2014MN01553 A IN 2014MN01553A IN 1553MUN2014 A IN1553MUN2014 A IN 1553MUN2014A IN 2014MN01553 A IN2014MN01553 A IN 2014MN01553A
Authority
IN
India
Prior art keywords
geranylgeranylacetone
adsorption
container wall
inhibited
lipophilic antioxidant
Prior art date
Application number
Inventor
MIYANOTakayuki
KUROSETakahiro
Original Assignee
Rohto Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohto Pharma filed Critical Rohto Pharma
Publication of IN2014MN01553A publication Critical patent/IN2014MN01553A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

An ophthalmic composition containing a geranylgeranylacetone and a lipophilic antioxidant wherein the adsorption of the geranylgeranylacetone into a container wall is significantly inhibited and as a result the decline in the content or concentration of the geranylgeranylacetone within the composition is significantly inhibited. Moreover the adsorption of the lipophilic antioxidant into the container wall is also inhibited by being combined with the geranylgeranylacetone.
IN1553MUN2014 2012-02-27 2013-02-25 IN2014MN01553A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012040675 2012-02-27
PCT/JP2013/054785 WO2013129322A1 (en) 2012-02-27 2013-02-25 Ophthalmic composition

Publications (1)

Publication Number Publication Date
IN2014MN01553A true IN2014MN01553A (en) 2015-05-08

Family

ID=49082519

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1553MUN2014 IN2014MN01553A (en) 2012-02-27 2013-02-25

Country Status (7)

Country Link
US (2) US20130303627A1 (en)
JP (2) JP5345746B1 (en)
CN (1) CN104136016A (en)
HK (1) HK1200109A1 (en)
IN (1) IN2014MN01553A (en)
TW (1) TWI565464B (en)
WO (1) WO2013129322A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014129466A1 (en) * 2013-02-19 2014-08-28 ロート製薬株式会社 Mucosal application agent for preventing, ameliorating or treating retinal disease
JP5483513B1 (en) * 2013-02-19 2014-05-07 ロート製薬株式会社 Mucosal application agent for prevention, improvement, or treatment of retinal diseases
WO2015029924A1 (en) * 2013-08-26 2015-03-05 ロート製薬株式会社 Ophthalmological composition
JPWO2015029926A1 (en) * 2013-08-26 2017-03-02 ロート製薬株式会社 Ophthalmic composition
TW201542196A (en) * 2013-08-26 2015-11-16 Rohto Pharma Ophthalmic formulation
US9421199B2 (en) * 2014-06-24 2016-08-23 Sydnexis, Inc. Ophthalmic composition
US20190350881A1 (en) 2016-06-17 2019-11-21 Ys Pharmtech Stabilization of epinephrine formulations
TW201807458A (en) * 2016-08-26 2018-03-01 鴻海精密工業股份有限公司 Ophthalmic lens, intraocular lens and package containing ophthalmic lens
CN115322095A (en) * 2021-01-27 2022-11-11 Ａｇｃ株式会社 Purification method of tafluprost

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3734521B2 (en) * 1993-12-21 2006-01-11 千寿製薬株式会社 Eye drops
JP3021312B2 (en) * 1994-03-15 2000-03-15 千寿製薬株式会社 Method for stabilizing pranoprofen and stable aqueous solution of pranoprofen
JPH08133967A (en) * 1994-11-02 1996-05-28 Eisai Co Ltd Agent for treating dry eye
JP3880265B2 (en) * 1998-11-16 2007-02-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 Aqueous solution of fat-soluble substances
JP2000319170A (en) * 1999-03-05 2000-11-21 Eisai Co Ltd Teprenone-containing eye lotion
JP3876355B2 (en) * 2000-09-13 2007-01-31 参天製薬株式会社 Ophthalmic solution
WO2010150378A1 (en) * 2009-06-25 2010-12-29 ライオン株式会社 Ophthalmic composition

Also Published As

Publication number Publication date
CN104136016A (en) 2014-11-05
WO2013129322A1 (en) 2013-09-06
JPWO2013129322A1 (en) 2015-07-30
JP5345746B1 (en) 2013-11-20
US20130303627A1 (en) 2013-11-14
TW201340961A (en) 2013-10-16
US20150025154A1 (en) 2015-01-22
HK1200109A1 (en) 2015-07-31
JP2013231067A (en) 2013-11-14
TWI565464B (en) 2017-01-11

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