MY170840A - Aqueous composition containing 2-amino-3-(4-bromobenzoyl) phenylacetic acid - Google Patents

Aqueous composition containing 2-amino-3-(4-bromobenzoyl) phenylacetic acid

Info

Publication number
MY170840A
MY170840A MYPI2014702590A MYPI2014702590A MY170840A MY 170840 A MY170840 A MY 170840A MY PI2014702590 A MYPI2014702590 A MY PI2014702590A MY PI2014702590 A MYPI2014702590 A MY PI2014702590A MY 170840 A MY170840 A MY 170840A
Authority
MY
Malaysia
Prior art keywords
bromobenzoyl
amino
phenylacetic acid
aqueous composition
composition containing
Prior art date
Application number
MYPI2014702590A
Inventor
Takashi Morimoto
Hiroyuki Asada
Kyohei Takahashi
Tomoyuki Okamoto
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of MY170840A publication Critical patent/MY170840A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to an aqueous composition comprising 2-amino-3-(4-bromobenzoyl)phenylacetic acid or a salt thereof, and optionally benzalkonium chloride and/or a polyoxyethylene sorbitan fatty acid ester. By means of restricting the contents of benzalkonium chloride and the polyoxyethylene sorbitan fatty acid ester to within specific ranges, a composition can be obtained in which the stability of 2-amino-3-(4-bromobenzoyl)phenylacetic acid or a salt thereof is maintained and there are no changes in appearance.
MYPI2014702590A 2012-03-28 2013-03-28 Aqueous composition containing 2-amino-3-(4-bromobenzoyl) phenylacetic acid MY170840A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2012073181 2012-03-28

Publications (1)

Publication Number Publication Date
MY170840A true MY170840A (en) 2019-09-10

Family

ID=49260248

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2014702590A MY170840A (en) 2012-03-28 2013-03-28 Aqueous composition containing 2-amino-3-(4-bromobenzoyl) phenylacetic acid

Country Status (9)

Country Link
JP (1) JP5922609B2 (en)
KR (1) KR20140139501A (en)
CN (1) CN104203224A (en)
IN (1) IN2014DN07767A (en)
MY (1) MY170840A (en)
PH (1) PH12014502171A1 (en)
SG (1) SG11201405837YA (en)
TW (1) TWI604858B (en)
WO (1) WO2013147000A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016199854A1 (en) * 2015-06-10 2016-12-15 参天製薬株式会社 Ophthalmic solution and method for maintaining preservative efficacy of ophthalmic solution
WO2019117252A1 (en) * 2017-12-14 2019-06-20 参天製薬株式会社 Eye drop containing 2-amino-3-(4-bromobenzoyl) phenylacetic acid or salt thereof
CN114224830A (en) * 2021-12-24 2022-03-25 辰欣药业股份有限公司 Single-dose bacteriostatic-free ophthalmic preparation and preparation method thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002308764A (en) * 2001-02-09 2002-10-23 Taisho Pharmaceut Co Ltd Pharmaceutical composition for ophthalmic use
WO2005046700A1 (en) * 2003-11-14 2005-05-26 Senju Pharmaceutical Co., Ltd. Aqueous solution preparation containing aminoglycoside antibiotic and bromfenac
CN1823754A (en) * 2006-03-28 2006-08-30 卢秀莲 Sodium bromophenolate eye drops and its preparation method
CN101313899B (en) * 2007-06-01 2012-02-29 北京德众万全药物技术开发有限公司 Medicament composition for eyes containing sodium bromfenac
BRPI0908502A2 (en) * 2008-02-21 2017-05-23 Ista Pharmaceuticals ophthalmic aines as adjuvants
CN101322683B (en) * 2008-07-30 2013-01-16 浙江三叶药业有限公司 Gel for eye containing bromfenac sodium hydrate and preparation thereof
WO2012099142A1 (en) * 2011-01-18 2012-07-26 千寿製薬株式会社 Bromfenac aqueous liquid composition having preservative efficiency
JP6012231B2 (en) * 2011-04-08 2016-10-25 ロート製薬株式会社 Bromfenac-containing composition

Also Published As

Publication number Publication date
CN104203224A (en) 2014-12-10
JP5922609B2 (en) 2016-05-24
TW201343197A (en) 2013-11-01
JP2013227300A (en) 2013-11-07
PH12014502171A1 (en) 2014-12-10
KR20140139501A (en) 2014-12-05
SG11201405837YA (en) 2014-11-27
WO2013147000A1 (en) 2013-10-03
TWI604858B (en) 2017-11-11
IN2014DN07767A (en) 2015-05-15

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