IN2015DN03975A - - Google Patents
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- Publication number
- IN2015DN03975A IN2015DN03975A IN3975DEN2015A IN2015DN03975A IN 2015DN03975 A IN2015DN03975 A IN 2015DN03975A IN 3975DEN2015 A IN3975DEN2015 A IN 3975DEN2015A IN 2015DN03975 A IN2015DN03975 A IN 2015DN03975A
- Authority
- IN
- India
- Prior art keywords
- novel
- potassium salt
- present
- monohydrate
- fimasartan potassium
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Abstract
The present invention relates to a novel monohydrate crystal form of fimasartan potassium salt which is excellent in moisture and temperature stability and which has a crystal particle size easy to control and which has superior homogeneity. The present invention provides a novel fimasartan potassium salt monohydrate.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20120113848A KR101490329B1 (en) | 2012-10-12 | 2012-10-12 | Fimasartan Potassium Monohydrate Crystal, Preparation Thereof And Pharmaceutical Composition Comprising Them |
PCT/KR2013/009097 WO2014058268A1 (en) | 2012-10-12 | 2013-10-11 | Monohydrate crystal of fimasartan potassium salt, method for preparing same, and pharmacological composition comprising same |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2015DN03975A true IN2015DN03975A (en) | 2015-10-02 |
Family
ID=50477658
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN3975DEN2015 IN2015DN03975A (en) | 2012-10-12 | 2013-10-11 |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP2927226A4 (en) |
KR (1) | KR101490329B1 (en) |
CN (1) | CN104854099B (en) |
AU (1) | AU2013330603B2 (en) |
BR (1) | BR112015008170A2 (en) |
CA (1) | CA2887056C (en) |
IN (1) | IN2015DN03975A (en) |
MX (1) | MX353635B (en) |
MY (1) | MY169064A (en) |
PH (1) | PH12015500794A1 (en) |
RU (1) | RU2613555C2 (en) |
SA (1) | SA515360275B1 (en) |
WO (1) | WO2014058268A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101545268B1 (en) * | 2015-02-05 | 2015-08-20 | 보령제약 주식회사 | Tablet and method of preparing the same |
CN105784867B (en) * | 2016-03-28 | 2019-01-01 | 北京睿创康泰医药研究院有限公司 | Make the purposes of reference standard for analyzing HPLC method and these impurity of the Fimasartan in relation to substance |
KR102247408B1 (en) | 2017-09-18 | 2021-05-03 | 보령제약 주식회사 | Fimasartan prodrug |
KR102402501B1 (en) * | 2018-04-24 | 2022-05-26 | (주)국전약품 | Fimasartan Tromethamine Salt and Pharmaceutical Composition Comprising the Same |
KR102221856B1 (en) | 2020-10-12 | 2021-03-02 | 유니셀랩 주식회사 | Novel crystalline polymorph of fimasartan |
KR20230062916A (en) | 2021-11-01 | 2023-05-09 | 그린케미칼 주식회사 | Fimasartan Anhydride Form A Crystal Polymorph and Method for the preparation thereof |
KR20230062917A (en) | 2021-11-01 | 2023-05-09 | 그린케미칼 주식회사 | Fimasartan monohydrate form B polymorph and Method for the preparation thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100300566B1 (en) * | 1994-09-17 | 2001-11-22 | 조생현 | Pyrimidinone derivative and method for preparation thereof |
KR19990081093A (en) * | 1998-04-25 | 1999-11-15 | 조생현 | Pyrimidinone compound, pharmaceutical composition containing the same, and preparation method thereof |
KR100617953B1 (en) * | 2000-03-23 | 2006-08-30 | 보령제약 주식회사 | A preparing process of pyrimidinone compound and the pharmaceutically acceptable salts thereof |
US7309788B2 (en) * | 2001-09-21 | 2007-12-18 | Boryung Pharmaceutical Co., Ltd. | Method for preparing pyrimidinone compound and pharmaceutically acceptable salts thereof |
KR100521980B1 (en) * | 2002-10-10 | 2005-10-17 | 보령제약 주식회사 | The preparation method for pyrimidinone compound and trihydrate of the salt of the pyrimidinone compound |
BR112013025222B8 (en) * | 2011-04-12 | 2020-05-05 | Boryung Pharm | antihypertensive pharmaceutical composition and use thereof |
-
2012
- 2012-10-12 KR KR20120113848A patent/KR101490329B1/en active IP Right Grant
-
2013
- 2013-10-11 AU AU2013330603A patent/AU2013330603B2/en not_active Ceased
- 2013-10-11 RU RU2015117524A patent/RU2613555C2/en active
- 2013-10-11 MX MX2015004573A patent/MX353635B/en active IP Right Grant
- 2013-10-11 EP EP13845572.0A patent/EP2927226A4/en not_active Withdrawn
- 2013-10-11 MY MYPI2015000875A patent/MY169064A/en unknown
- 2013-10-11 CN CN201380063465.5A patent/CN104854099B/en active Active
- 2013-10-11 IN IN3975DEN2015 patent/IN2015DN03975A/en unknown
- 2013-10-11 CA CA2887056A patent/CA2887056C/en not_active Expired - Fee Related
- 2013-10-11 BR BR112015008170A patent/BR112015008170A2/en not_active Application Discontinuation
- 2013-10-11 WO PCT/KR2013/009097 patent/WO2014058268A1/en active Application Filing
-
2015
- 2015-04-10 PH PH12015500794A patent/PH12015500794A1/en unknown
- 2015-04-12 SA SA515360275A patent/SA515360275B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN104854099B (en) | 2016-11-16 |
MX353635B (en) | 2018-01-22 |
AU2013330603B2 (en) | 2016-03-31 |
MX2015004573A (en) | 2015-07-21 |
CN104854099A (en) | 2015-08-19 |
WO2014058268A1 (en) | 2014-04-17 |
MY169064A (en) | 2019-02-12 |
SA515360275B1 (en) | 2017-07-11 |
RU2015117524A (en) | 2016-12-10 |
EP2927226A1 (en) | 2015-10-07 |
EP2927226A4 (en) | 2016-07-13 |
PH12015500794A1 (en) | 2015-06-15 |
KR20140047483A (en) | 2014-04-22 |
RU2613555C2 (en) | 2017-03-17 |
CA2887056A1 (en) | 2014-04-17 |
AU2013330603A1 (en) | 2015-05-28 |
KR101490329B1 (en) | 2015-02-04 |
BR112015008170A2 (en) | 2017-07-04 |
CA2887056C (en) | 2017-09-05 |
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